ML20049J246
| ML20049J246 | |
| Person / Time | |
|---|---|
| Site: | Waterford  |
| Issue date: | 03/27/1982 |
| From: | Epstein S JOINT INTERVENORS - WATERFORD |
| To: | |
| Shared Package | |
| ML20049J211 | List: |
| References | |
| NUDOCS 8203120305 | |
| Download: ML20049J246 (42) | |
Text
f -
C O, M.. . E.T. E P UNITED STATFS OF AMERICA NUCLEAR REGULATORY COMMISSION '82 WR 10 P1 MO BEFORE Tile ATOMIC SAFETY & LICENSING BOARD In the Matter of ,
LOUISIAN A POWER & LIGilT COMPANY Docket No. 50-382 (Waterford Steam Electric Station Unit 3)
SWORN STATEMENT OF DR. SAMUEL S. EPSTEIN
- 1. By whom are you employed and what position (s) do you hold?
Answer. I am employed as a Professor of Occupational and Environmental Medicine in the School of Public IIcalth, University of Illinois Medical Center in Chicago. I am also employed as the Director of the Occupational Toxicology Programs, Great Lakes Center of Occupational Safety and Health.
l 2. Is this in a specialized health field? If so, wnat is the description of the type of health field?
Answer. Yes - Occupational and environmental medicine.
- 3. What previous positions have you held?
Answer. Until 1979, I was the Director of Environmental IIcalth Resource Center, State of Illinois. For five years prior to that, I held the Swetland Professorship of Environmental IIcalth and Iluman Ecology, Professorship of Pharmacology, and was Director of Environmental llealth Programs, at Case 8203120305 820308 .
. e Western Itcserve University, School of Medicine, Cleveland Ohio. For ten years, until 1971, I was Chief of Laboratories of Carcinogenesis and Toxicology, Applied Microbiology and Ilistology at The Children's Cancer Research Foundation, Inc., Boston, Massachusetts. I also held a number of positions specializing in pathology, microbiology and carcinogenesis going back to 1952.
- 4. What are your academic qualifications and degrecs?
Answer. B.Sc. (Physiology) London University, England (1947); M.B.B.S.
(Bachelor of Medicine, Bachelor of Surgery) (Double Ilonors), London University, England (1950); D.T.M . II. (Diploma of Tropical Medicine and Ilygiene, l Bacteriology and Parasitology), London University (1952); D. Path. (Diploma of Pathology) London University (1954); M.D. (Doctorate of Medicine, Thesis in Pathology and Bacteriology) London University, England (1958); Diplomate, in i Public ilcalth and Medical Laboratory Microbiology, of the American Board of Microbiology (1963); Fellow of the lloyal Society of IIcalth, England (1971);
Montefiore Gold Medal in Tropical Medicine, Montefiore Prize in Tropical Ilygiene and Ranald Martin Prize in Military Surgery, lloyal Army Medical Corps (1953); Society of Toxicology,1969 Achievement Award; and Fellow of the New York Academy of Sciences,1975.
- 5. llave you done any research in the fields of cancer and/or human exposure to radiation?
Answer. Yes.
- 6. Please describe your research.
l Answer. Much of my research has been on mutagenicity, teratogenicity and carcinogenicity of environmental toxins. The cancer research I have done relates chemicals in the environment to human health. The data from this research ins linked cancer with chemicals found in municipal drinking water and
- - w, - * , - - , , a, . - - - - - - - - - . - , - - - - - - - -- c e w e- , ,- - -
. -. L urban alt. This research has indicated the synergistie effects of combining two or more carelaogens.
- 7. What publications have your works appeared in?
Answer. Nature, Science, C_ancer Research, Toxicology and Applied 3
Pharmacology, International Journal of Cancer, Biochemical Pharmacology, 1
Cancer Journal for Clinicians, Genetics, Mutation Research, Environmental Pathology, and many others.
- 8. Which of your publisted works deal with the areas of your research?
Answeg i'
The synergistic toxicity' and carcinogenicity of Freons and piperonyl butoxide. Nature, 214: 526-528, 1967.
i j Carcinogenicity of organic extracts of atmospheric pollutants. J. Air i
, Poll. Control Assoc., 17, 728-729, 1967.
i Enhancement bypiperonyl butoxide of acute toxicity due to Freons, benzo (a) pyrene, and griseofulvin in infant mice. Toxicol. Appl.
Phar macolo.,1_l, 442-448,1967.
Use of mammals in a practical screening test for chemical mutagens in the human environment. Nature, 219, 385-387, 1968.
r In vivo inhibition of mouse liver microsomal hydroxylating systems by
, methylenedioxyphenyl insecticidal synergists and related compounds. Life Sci., 7,10 51-1062,1968.
Cancer and mutation-producing chemicals in polluted urban air. Air -
Pollution (Air Quality Criteria) IIcarings before the Sub-committee on Air and Water Pollution of the Committee on Public Works. U. S. Senate,90th Congress. Washington, D.C.,1968, Chairman, Senator Edmund S. Muskie.
)
1
.n-. -, . - - , - , . .- , ,a ., - - - - , , , - . . . n-.-, - ,,..------..--,.-a --
--.,_.--,---,,..n. , , , , , -,,--..--m.,-n..--v,w---, --- , - -- e
Chemical In /.ards in the human envirca ment. Ca-A Cancer Journal for Clinicians, 19, 277-281, 1969.
Synergism in carcinogenesis with particular reference to synergistic effects of piperonyl butoxide and related insecticidal synergists. Chapter, pp. 21-42. In, Chemical Tumor Problems, ed. Nakahara, W., Pub. Japanese Society for the Promotion of Science, Tokyo, Japan,1970.
Chronie biological hazards due to chemicals. In, Birth Defects and Fetal Develop _ meg. Chapter 9, pp.13G-166. Ed. Moghissi,11., C. C. Thomas.
Publ., Springfield, 111., 1974.
Adverse health effects and chemical pollutants of the environment.
Cinpter 8. !c l'qvironment: llesources, Pollution and Society, 2nd. edition.
Editor, Munloch, W. N., Publisher, Sinauer Associates,1975.
Drinking water and cancer mortality in Louisiana. Science, 193, 55-07, 1976 ,
Potential carcinogenic hazards due to contaminated drinking water.
Proceedings of the hternational Conference on Biological Control of Water Pollution, 00 73-84, Editors, Tourbier, J. and Pierson, R. W., University of Penns31 vania Press,1976.
Carcinogenicity of a composite organie extract of urban particulate atmospherie pollutants following subcutaneous injection in infant mice.
Environmental lies. 19, 163-176, 1979.
Enviro 7m ental determinants of human cancer. Cancer Res. 34:
2425-2435, 1974.
Acute synergistic toxicity and hepatic necrosis following oral administration of sodium nitrite and secondary amines to mice. Cancer R es., 31,: 1201-1205, 1971.
Additive and synergistic inhibition of mammalian microsomal enzyme functions by piperonyl butoxide, safrole and other methylenedioxyphenyl derivatives. Experientia. 27, 1052-1054, 1971.
"Adveme lluman Effects due to Chemical Pollutants". at IIcarings before the Subcommittee on Executive Reorganization and Government Research , of the Committee on Government Operations, U. S. Senate Washington, D.C., April 6,1971. Chairman, Senator Abraha m Ribicoff.
- 9. Do you have any as yet unpublished research da,ta compiled?
Answer. Yes: ,
"The Price We Pay for Prodress: The Ilazards of the IIalogenated Ilydrocarbons." Proceedings International Conference, "Chemis-try-Man-Environment: Italogenated Ilydrocarbons," Gottlieb Duttweiler Institute, Zurich, Switzerland, October 13-15, 1980.
In vivo iepair of DNA damage in the guinea pig pancreas following 4-hydroxyairinoquinoline-1 -oxide administration.
Analyses of Carcinogenesis Dose Response Relations Using Dichotomous Data: Implications for Carcinogenic Risk Assessment.
- 10. llave you participated in eny scientific colloquia?
f uswer. Yes. I participated in the Second International Conference of Protozoology in London, in which I presented the paper entitled "13icassay for polycyclic atmospheric pollutants and for untioxidants based on photodynamie
! response of protozoa"; the ICF International Occupational IIcalth Conference in Geneva (October 20-30, 1974), in which I presented the paper " Carcinogens in industry: needed studies"; the International Conference on Enviroamental .
Sensing and Assessment in Las Vegas (September 14-19, 1975), in which I presented the paper "N- Nitroso Compounds in the Environment"; U1e l
l
Internatic al Conference on Biolog cal Control of Water Pollution, in which I presented the paper " Potential carcinogenic hazards due to contaminated drink-ing water"; the Conference on Occupational Carcinogencais (March 24,1976), in which I presented the paper " Aldrin und dicidrin - Suspension based on environ-mental eviderve and evaluation of societal needs"; the LASL Third Life Sciences Symposium, Los Alamos, New Mexico (October 15-17, 1975), in which I presented the paper "IMveloping health policies at:d standards; llesponsibility of the scientist in developh:J and interpreting 'Public Interest' viewpoints"; the Inter-national Symposium on N-Nitroso Compounds, Budapest (October 16-20), in
~
which I presented the papers " Kinetics of Nitrosamine Formation in Mice Following Oral Administration of Trace-Level Precursors" imd "In Vivo Nitrosation of Morpholine in Mice by Inhaled NO2"; and the International ,
Symposium on N-Nitroso Componnds, Tokyo Japan (September 28-October 1, 1981), in which I presented the paper 3 Vivos Nitrosation of Amines by Inhaled Nitrogen Dioxide and Inhalation of tha Biosynthesis of Nitrosamines."
- 11. llave you 4.eer appeared as an expert witness in state, federal or congressional hearings or courts?
Answer. I appeared at the Air Pollution (Air Quality Criteria) Hearings
! before the Subcommittee on Air and Water Pollution of the Committee on Public Works, of the U. S. Senate,90th Congress, in 1968, chaired by Senator Edmund S.
Muskie. I also appeared at IIcarings before the Subcommittee on Executive Reorganization and Government Research of the Committee on Government Operations of the U. S. Senate in 1976, chaired bj Senator Abraham Ribicoff.
- 12. Would you please define synergism and indicate how this phenomen would affect hanh risks to a population.
Answer. Synergisin is tiie interaction between individual carcinogens which makes the total effect of the carcinogens working together much more potent th.in the expected effects if each carcinogen were operating independently.
- 13. Are you aware of any studies which demonstrate the presence of carcin-ogens in the municipal drinking water in parishes along the lower Mississippi?
A nswer. Yes. According to a study by liarris, Page and Reiches, which was a follow-up to a study I previously performed, ' Numerous studies have demonstrated the presence of chemical carcinogens in river water and in treated municipal drinking water. R ecent studies have also demonstrated that chlorination of drinking water, particularly if the source is heavily polluted with organic chemicals, results in the production of a variety of chlorinated hydro-carbons, some of which are carcinogenic. Furthermore, drinking water may be contaminated by organie chemicals migrating from materials used in conveyance systems. For example, the Environmental Protection Agency (EPA) has recently observed that vinyl chloride contaminate's water carried by polyvinyl chloride piping at concentrations up to 55 micrograms per liter when water stands in the piping for long periods of time.
" Additional studies documenting the chemical contamination of drinking-water supplies include a 1970 U. S. Public IIcalth Service survey which found thrit the levels of organie chemicals in many water supplies exceeded the Public ilcalth Service's recommended limit (McCaber, et al.1970). A 1972 EPA report identified 46 potentially carcinogenie or otherwise toxic organic chemi-cals in the drinking water of three communities along the lower Mississippi River in Louisiana (EPA 1972). A second EPA study in 1974 identified 66 organic chemicals in the New Orleans drinking water (EPA 1974). These and other i
similar studies viere cited by the EPA as the reasons for initiating the National Organies Rcconnaimance Survey (NOltS) in November,1974, to clarify to what extent organics are present in the nation's drinking water (EPA 1975b)".
- 14. Are you aware of any studies in which the presence of these carcinogens ins been linked to high cancer mor'ality rates in these parishes along the alississippi River?
Answer. Yes. According to the llarris study, even at these "relatively low levels of exposure, preliminary epidemiologie studies of aggregate populations in Louisiana, Ohio, and New Jersey support the hypothesis that carcinogens in drinking water are related to hun $an cancer. . . .
"Because of the historical evidence of high cancer rates in New Orleans and the results of EPA tests demonstrating the presence of numerous carcino-gens in New Oricans drinking water, two recent studies (IIGarris 1974; Page et al.1976), using mutivariate regression techniques, have investigated the rela-tionship between drinking-water qu:llity and cancer mortality rates for the period 1950-1969 by parish in Louisiana. Exposure variables were chosen from the epidemiologic literature to reflect those environmental, social, and demo-graphie variables generally associated with human cancer. Included were urbanization, family income, occupation, poulation density, and source of drink-ing water. The results of these studies indicated a statistically significant association between cancer mortality rates and pc,pulations which received drinking water from the 11ississippi River."
- 15. Can you make a statement as to the possible aggravation of existing cancer incidence which might result from the introduction of low level radiation
~
into the drinking water?
Answer. There are well-documented instances in naimal studies of st^ong synergistic effects produced by chemicals in combinatino with radiation, viruses, or ot' er ehemicals. The epidemiological patterns of certain human cancers implicat cornbined effects of multiple agents (e.g., inhalation of radon and radon daughters in uranimum mines and cigarette sinoking).
- 16. In view of the studies you mentioned which predict latency periods of 20 to 30 years, would you expcet these latency periods to be shortened by the effects of low !cvel radiation in the total environment? Also, given the fact tint present day studies are based on health effsets that are the result of exposures ten to twenty years ago, what would you expect to happen to the cancer incidence with the increasing level c,f industrial activity?
Answer. Yes, with the addition of a known carcinogen to an already existing one, the period before onset (the latency period) is shortened.
Adverse health effects linked with carcinogens in the environment can be expected to become more pronounced as the level of these carcinogens in the environment increases. It should be kept in mind that we are just now seeing the consequences of exp >sures of ten to twenty years ago.
- 17. From your early research reported in Science, what perceninge of drinking water for municipalities downstream froin Waterford Three is taken from the 31ississippi lliver?
Answer. Jefferson, Orleans, Plaquemines, St. Bernard, St. Charles and St.
John the Baptist Parishes talce 100% of their municipal water supply from the 31ississippi lliver and have no alternative supplies.
- 18. What were the results of this 976 study?
Answer. Alultivariant regression analysis l'ndicates a statistically signifi-cant relation between cance: mortality rates in Louisiana and drinking water l
l
4 obtained from the Mississi ,pi f(iver. This is true for total cancer, cancer of the urinary organis, and cancer of the gastrointestinal tract.
- 19. Are you aware of the findings of the Ad Iloe Coinmittee on the Evaluation of Environmental Carcinogens, which states that " Physical factors are known to cause caneers in man and aniinals. For exninple, ultraviolet i radiation causes skin cancer, and ionizing radiation cancer of various organs (e.g., leukemias, lung cancer, bone s,arcomas, skin ' cancer). . . .
Strong epidemiologic and experimental evidence indicates the existinee of.
a direct dose-response relatinoship between exposure to radiation and T -u carcinogenic effects. . . . Evaluation of radiation hazards has been W
approached through measurement of the total cumulativo dose of radiadon exposure."?
Answer. Y es. These findings point out that there is no safe level d radia tion. At background radiation levele, there are adverse health effects, just as at higher levels. Any addition of radiation into the environment, regardless of
~
the level, compounds these effects.
- 20. Can you make a statement with regard to the health risk from low Icvel radiation in emissions from Waterford Thrr4e as it affects a population already at risk from high levels of chemical carcinogens?
Answer. The introduction of low level radiation into an environment high in chemical carcinogens places the population at a much higher risk than a o
population without these chemicals. The two careir,5 gens act synergistically to produce higher cancer incidence tinn would be expected as a result of J.ieh one l
acting independently.
- 21. In your view, is the health risk associated with carcinogens (either radiation or chemical) cumulative in a population from generation to generation? '
t l
l
Answer. Yes. The risk is definitely of a cumulative nature. !!calth risks
, s
' ~~
to a population cannot be considered on a year-to-year basis. The effects of cumulative risk factors are carried over for years and are passed down to future generations.-
vsa, I*
l
+
.W,
' ~
r t
l.
r .
i STATE OF ILLINOIS COUNTY OF dO/;
AFFIDAVIT BEFORE h1E, the undersigned . authority, duly authorized to administer oaths, there did appear DR. SAh1UEL S. EPSTEIN, a person of full age and a resident of the county of OOg_ , state of Illinois, who being duly sworn on oath, did state that the answers to qcestions presented herein are all true and corrcet to the best of his knowledge, information and belief; and that all such answers were prepared at his direction.
- I M)
Dil. SAh1UEL S. EPSTEIN m:s uv,x (! f SWORN TO AND SUI 3 SCRIBED BEFOllE.h1E, TillSM7d DAY OF Mg2ed ,1982.
NOTAt 1 Acw PU13LIC FOR Tile COUNTY-w OF _ _ d qoc _
STATE OF ILLINOIS.
My commission expires at /ojb ([E'6.
4
l CC'M!.TfD
\
SAMUEL S. EPSTEIN , .
PERSONAL: Born April 13, 1926, Middlesborough, Yorkshire, England.
Naturalized U.S. citizen. Married, 'Ihree Children Professional address: School of Public Health, University of Illinois Medical Center, P. O. Box 6998, Chicago, Illinois 60680.
QUALIFICATIONS: ,
1947 B.Sc. (Physiology) Iondon University, England.
1950 M.B.B.S. (Bachelor of Medicine, Bachelor of Surgery)
(Double Honors) London University, England .
1952 D.T.M.H. (Diploma of Tropical Medicine and Hygiene, Bacteriology and Parasitology) Inndon University.
1954 D. Path. (Diploma of Pathology)Iondon University 1958 M.D. (Doctorate of Medicine, Thesis in Pathology and Bacteriology) Iondon Universityg England.
1963 Diplomate, in Public Health and Medical Laboratory Microbiology, of the American Board of Microbiology.
1971 Fellow of the Royal Society of Health, England.
2 ,
POSITIONS HELD:
1950: Demonstrator, Morbid Anatomy, Guy's Hospital, London.
1951: House Physician, St. John's Hospital, London.
1952: Postgraduate Student in Tropical Medicine, Pathology Bacteriology and Parasitology, Royal Army Medical College, London.
1952-1955: Specialist in Pathology, Royal Army Mcdical Corps.
1955-1958: Lecturer in Pathology and Bacteriology, Institute of Laryngology and Otology, University of London.
1958-1960: British Empi're Cancer Campaign Research Fellow, in conjunction with the Chester Beatty Cancer Essearch Institute, and Tumor Pathologist at the Hospital for Sick Children, Great Ormond Street, London.
1960: Consultant in Pathology, The Memorial Hospital, Peterborough, England.
1961-1971 Research Associate in Pathology and Microbiology, The Children's Hospital Medical Center and the Children's Cancer Research Foundation, Inc., Boston, Mass.
1961-1971: Chief, Laboratories of Carcinogenesis and Tbxicology, Applied Microbiology and Histology, The Children's Cancer Research Foundation, Inc., Boston, Mass.
1962-1971: Senior Research Associate in Pathology, The Children's Cancer Research Foundation, Inc., Boston, and Research Associate in Pathology, Harvard Medical School, Boston.
1971-1976: Swetland Professor of Environmental Health and Human Ecology; Professor of Pharmacology; Director Environmental Health Programs, Case Western Reserve University, School of Medicine, Cleveland, Ohio. .
1976 to date: Professor of Occupational and Environmental Medicine, School of Public Health, University of Illinois at the Medical Center, Chicago, Illinois.
1978-1979 Director, Environmental Health Resource Center, State of Illinois 1980 - Director, Occupational Toxicology Programs, Great Lakes Center Occupational Safety and Health.
l AWARDS:
- 1. Military Awards in Royal Army Medical Corps, 1953 (a) Montefiore Gold Medal in Tropical Medicine (b) Montefiore Prize in Tropical Hygiene (c) Ranald Martin Prize in Military Surgery
- 2. Society of Toxicology, 1969 Achievement Award
- 3. Fellow of the Royal , Society of Health,1971.
- 4. Fellow of the New York Academy of Sciences, 1975.
SOCIETY MEMBERSHIPS:
- 1. Society for Pathology and Bacteriology
- 2. Society for General Microbiology
- 3. Society of Protozoologists
- 4. Air Pollution Control Association
- 5. American Association of Pathologists and Bacteriologists
- 6. American Society for Experimental Pathology
- 7. American Association for Cancer Research
- 8. American Board of Microbiology l 9. Society of Tbxicology i
- 10. Environmental Mutagen Scciety
[ 11. American Association for Advancement of Science l
- 12. Society for Occupational and Environmental Health l
- 13. New York Academy of Sciences.
l i
l I
l i
l . - , - ,- , - . . . - , - , - -
i 4
COMMITTEES AND CONSULTANTSHIPS:
- 1. Member, Society of Protozoologists Comnittee on the Relation of Protozoology to Public Health, 1962-1968.
- 2. Chairman, Committee on Biological Effects of Air Pollution, Air Pollution Control Association, 1963-1973.
- 3. Member, Technical Council of the Air Pollution Control Association, 1963-1973
- 4. Executive Secretary, Environmental Mutagen Society, 1969-1972.
- 5. Chairman, 1969, HEW Panel, Mutagenicity of Pesticides, "Mrak Commission".
- 6. Chairman, 1969, HEW Panel, Teratogenicity of Pesticides, "Mrak Commission".
- 7. Member, 1968, HEW Panel, Pesticide Interactions,"Mrak Commission".
- 8. Member,1969, HEW Panel, Carcinogenicity of Pesticides, "Mrak Commission".
- 9. Chairman, NIMH Panel on Chronic Non-psychiatric Hazards of Drugs of Abuse, 1969.
- 10. Consultant to the Committee on Public Works, United States Senate, 1970-1974.
- 11. Chairman, Effects Division, Technical Council, Air Pollution Control Association, 1970-1973.
- 12. Consultant, Center for Studies of Narcotic and Drug Abuse, National Institute of Mental Health, 1970-1973.
- 13. Consultant to the Panel on Polycyclic Organic Matter, National Academy of Sciences, National Research Council,1970.
- 14. Consultant to the Pesticide Board of the State of Massachusetts, 1970-1971.
- 15. Consultant, U.S. Senate Sub-committee on Executive Reorganization and ,
Government Research, Committee on Government operations, 1971.
I
- 16. President-elect, Society for Occupational and Environmental Health, 1972-1974.
5 5
\
COMMITTEES AND CONSULTANTSHIPS (cont.):
- 17. Member, National Air Quality Criteria Advisory Committee, Environmental Protection Agency, 1972-1975.
- 18. Member, Department of Labor Advisory Committee on Occupational Carcinogens, 1973.
- 19. Consultant, Industrial Union Department, AFL/CIO, 1973 to date.
- 20. Ad Hoc Consultant Oil Chemical and Atomic Workers Union, 1968 to d.-s te .
- 21. Ad, Hoc Consultant Textil'c Workers Union, 1972 to date.
- 22. Chairperson Occupational Task Force, State of Ohio, 1974-1975.
- 23. President, The Society for Occupational and Environmental Health, 1974 - 1976.
- 24. Consultant, Office of General Counsel (on Aldrin and Dieldrin) ,
Environmental Protection Agency, 1974.
- 25. Consultant, Office of General Counsel (on Chlordane and Heptachlor),
Environmental Protection Agency, 1975 to date.
- 26. Member, Environmental Health Advisory Committee, Environmental Protection Agency, 1975 to date.
- 27. Consultant, Occupational Safety and Health Administration, Department of i
Labor, 1977 to date.
l 0
a - - .
6 ;
i PUBLIC INTEREST GROUPS AND ORGANIZATIONS:
i
- 1. President, Rachel Carson Trust, Washington, D.C., 1974 to date.
- 2. Chairperson, Commission for the' Advancement of Public Interest Organizations, Washington, D.C., 1974 to date.
' /
- 3. Member, Advisory Council Center for Science in the Public Interest.
- 4. Member, Science Advisory Board for the Journal, Environment.
- 5. Member, Board of Directors, Consumers Union of United States, Inc.,
Mount Vernon, N.Y.
t I
i I
o e
l I
h t
i i
I f
I i
l __ _ , _ . - _ _ _ _ _ _ _ - . _ . . _ _ _ _ . _ _ _ . - . - , _ _ _ . _ . __ _ . , _ _ , _ _ _ _ _ _ _ . . _ _ . _ _ , _ , _ _ _ _ _ , _ . _ . . _ . _ _ _ _ _ _ _ _ _ .
i 7
PUBLICATIONS AND TESTIMONY (
- l. Epstein, S. S., and Winston, P.:
In,tubation granuloma.
J. Larnygol. Otol. , 71: 17-38, 1957.
- 2. Epstein, E. S., Winston, P., Friedmann, I., and Ormerod, F. C.:
The vocal cord polyp.
J. I/.ryngol. Otol., 71: 673-688, 1957.
- 3. Epstein, S. S. and Shaw, H. J.:
Metastatic cancer of the larynx as a cause of carotid-sinus syndrome.
Cancer, 10 : 933-937, 1957.
- 4. Epstein, S. S.: ,
An intra-oral inoculation technique for the production of experimental (
pneumonia in mice.
J. Hygiene, 56: 73-79, 1958.
- 5. Epstein, S. S. and Stratton, K.:
Further studies in the mouse intra-oral inoculation technique.
J. Hygiene, 56: 81-83, 1958.
- 6. Epstein, S. S. and Shaw, H. J.:
Multiple malignant neoplasms in the air and upper food passages.
Cancer, l_l,: 326-332, 1958
- 7. Winston, P. and Epstein, S. S.:
Papilloms of the larynx: A clinico-pathological study.
J. Laryngol. Otol., 72, 452-464, 1958.
- 8. Epstein, S. S. and Friedmann, I.:
Klebsiella serotypes in infections of the ear and upper respiratory tract.
J. Clin. Path., 2: 359-362, 1958.
! 9. Epstein, S. S.:
} A " stripping" technique for the examination of the total epithelial surface of the larynx.
J. Path. Bact., 75: 472-473, 1958.
- 10. Freeman, T., Wakefield, G. S., and Epstein, S. S.
Platelet-agglutinating factor in glandular fever complicated by jaundice and thrombocytopenia.
Lanc'e t , 383-385, Oct. 25, 1958.
l 11. Epstein, S. S. and Bradbeer* T. L.:
l A case of primary diptheritic otitis media, l
J. Laryngol . Otol . , 72 : 1001-1003, 1958.
l l
l
'?
u -
PUBLICATIONS (cont.)
12, Epstein, S. S.:
Experimental Klebsiella pneumonia in mice with particular reference to periarterial changes.
J.' Path. Bact., 78j 389-396, 1959.
- 13. Epstein, S. S. .
i The biochemistry and antibiotic sensitivity of the Klebsiella.
J. Clin. Path., 12: 52-58, 1959.
- 14. Epstein, S. S. and Payne, P. M.:
The effect of some variables on experimental Klebsiella infections in mice.
J. Hygiene, 57: 68-80, 1959.
- 15. Shaw, H. J. and Epstein, S. S.:
Cancer of the epiglottis.
Cancer, 12: 246-256, 1959.
- 16. Epstein, S. S. and Weiss, J. B.:
The extraction of pigments from Euglena gracilis.
Biochem. J., 75,3 247-250, 1959.
- 17. Timmis, C. M. and Epstein, S. S. :
New antimetabolites of Vitamin B 2
Nature, 184: 1383-1384, 1959.
- 18. Epstein, S. S., Payne, P. M., and Shaw, H. J.:
Multiple primary malignant neoplasms in the air and upper food passages.
Cancer, 13,: 461-463, 1960,
- 19. Epstein, S. S and Weiss, J. B.: .
Measuring the size of isolated cells.
Nature, 187: 461-463, 1960.
- 20. Epstein, S. S.:
Effects of some benzimidazoles on a Vitamin B -requiring alga.
2 Nature, 188: 143-144, 1960.
- 21. Epstein, S S., Weiss, J. B., Bush, P., and Causley, D.:
Vitamin B and growth of Euglena gracilis .
12 '
Fed. Proc., 20,(1) : 450, 1961.
- 22. Epstein, S. S. and Timmis, G. M.:
" Simple" Vitamin B antimetabolites.
- Proc. Amer. Assoc.bancerRes., 3(3): 223, 1961.
- 23. Epstein, S. S. and Burroughs, M.:
Some factors influencing the photodynamic responsc of Paramecium caudatum to 3,4-benzpyrene.
Nature, 193: 337-338, 1962.
6
- )
PUBLICATIONS (cont.)
\
- 24. Epstein, S. S., Burroughs, M., Small, M., and Verbrugghen, M.:
The photodynamic toxicity of polycyclic hydrocarbons.
Proc. Amer. Assoc. Cancer Res . , 3,(4 ) : 316, 1962.
- 25. Epstein, S. S., Weiss, J. B., Causeley, D., and Bush, P.:
Influence of Vitarc ? n the size and growth of Euglena gracilis.
2 J. Protozool., 9: 33u 5 339, 1962.
- 26. Epstein, S. S. and Timmis, G. M.:
Effect of Vitamin B antagonists and other compounds on the C1300 tumor.
Biochem. Pha rmacol . ,211,: 743-746, 1962.
- 27. Epstein, S. S. and Timmis, G. M.:
Simple antimetabolites of Vitamin B 2
J.Protozool., 10: 63-73, 1963.
- 28. Epstein, S. S., Burroughs, M., and Small, M.:
The photodynamic effect of the carcinogen 3,4-benzpyrene on Paramecium caudatum.
Cancer Res., 23: 35-44, 1963.
- 29. Epstein, S. S., Small, M., Koplan, J., and Mantel, N.:
Photodynamic bioassay of benzo (a) pyrene using Paramecium caudatum.
J. Nat. Cancer Inst., 31: 163-168, 1963.
- 30. Epstein, S. S., Small, M., Jones, H., Koplan, J., and Mantel, N.:
A photodynamic bioassay of atmospheric pollutants.
Proc. Amer. Assoc. Cancer Res., 4 (1) : 18, 1963.
- 31. Epstein, S. S.:
Photodynamic activity of polycyclic hydrocarbon carcinogens.
Acta Unio Internat. Contra Cancrum, 19,: 3/4, 599-601, 1963.
- 32. Epstein, S. S., Small, M., Koplan, J., Mantel, N., Falk, H.L., and Sawicki, E.:
Photodynamic bioassay of polycyclic air pollutants.
A.M.A. Arch. Env. Health, 7:531-537, 1963.
- 33. Small, M., Jones, H., and Epstein, S. S.:
Photodynamic activity of polycyclic compounds.
Fed. Proc., 22,: 316, 1963.
- 34. Epstein, S. S., Small, M., Falk, H.L., and Mantel, N.:
On the association between photodynamic and carcinogenic activities in polycyclic compounds. ,
Cancer Res., 24: 855-862, 1964.
- 35. Foley, G. E. and Epstein, S. S.:
Cell culture and cancer chemotherapy.
In " Advance in Chemotherapy", 1: 1964, Academic Press. New York.
i 10 PUBLICATIONS (cont. )
b6. Epste'in, S. S., Bulon, I., Koplan, J., Small, M., and Mantel, N.:
Charge-trar 3fer complex formation, carcinogenicity and photodynamic activity in polycyclic compounds.
Nature, 204: 750-754, 1964.
- 37. Epstein, S. S., Bulon, I., and Koplan, J.:
Charge transfer complex formation, carcinogenicity and photodynamic activity in polycyclic compounds.
Fed. Proc., 23,(2) : 287, 1964.
- 38. Epstein, S. S.:
Photoactivation of polynuclear hydrocarbons.
A.M.A. Arch. Env. Health., 10,: 233-239, 1965.
- 39. Epstein, S. S., Small, M.', Sawicki, E., and Falk, H. L.:
Photodynamic bioassay of polycyclic atmospheric pollutantsk.
J. Air Poll. Control Assoc., 15: 174-176, 1965.
- 40. Epstein, S. S.: /
A simple photodynamic assay for polycyclic atmospheric pollutants.
World Health Organization Report, WHO/EBL/51,1965.
- 41. Epstein, S. S., Saporoschetz, I. B., Small, M., Park, W., and Mantel, N.:
A simple bioassay for antioxidants based on protection of Tetrahymena pyriformis from the photodynamic toxicity of benzo (a) pyrene.
Nature, 208: 655-658, 1965.
- 42. Small, M., Brickman, E. , and Epstein, S.S. :
Uptake of polycyclic compounds by phagotrophic protozoan.
Fed. Proc., 24: 684, 1965.
43, Epstein, S. S., Forsyth, J., and Bulon, I.:
A simple bioassay for antioxidants.
Fed. Proc., 24: 623,1965.
44 Epstein, S. S.:
' Bioassay for polycyclic atmospheric pollutants and for antioxidants based on phot 9d ynamic response of protozoa.
Abstract from }Second International Conference of Protozoology, London, Reprinted from Excerpta Medica International Congress, Series 91, August, 1965.
- 45. Epstein, S. S.:
The lung as a transplant site for malignant tumors in rodents.
Cancer, 19: 454-457, 1966.
- 46. Epstein, S. S., and Joshi, S. R.:
Obstructive renal failure in random-bred Swiss mice.
Fed. Proc., 25,: 237, 1966.
t 11 PUBLICATIONS (cont.)
- 47. Epstein, S. S., Saporoschetz, I. B., and Mantel, N.: (
Interactions between antioxidant and photosensitizer in the photodynamic bicassay for antioxidants.
Life Sciences, 5: 783-793, 1966.
- 48. Epstein, S. S., Forsythe, J., Saporoschetz, I. B., and Mantel, N.
An exploratory investigation on the inhibition of selected photo-sensitizers by agents of varying antioxidant activity.
Rad . Re s . 23, 322-335, 1966. ,
- 49. Epstein. S. S. and Tabor, F. B.: l Photosensitizing compounds in extracts of U.S.A. drinking water. I Science, 154(3746): 261-263, 1966.
- 50. Epstein, S. S.: .
Two sensitive tests for carcinogens in the air.
J. Air Poll. Control Assoc.,16,(10): 545-546, 1966.
- 51. Epstein, S. S., Joshi, S., Andrea, J., Mantel, N., Sawicki, E., Stanley, T.,
and Tabor, E. C.:
Carcinogenicity of organic particulate pollutants in urban air after administration of trace quantities to neonatal mice.
Nature, 212: 1305-1307, 1966.
- 52. Small, A., Mantel, N., and Epstein, S. S.:
i The role of cell-uptake of polycyclic compounds in photodynamic injury of Tetrahymena pyriformis.
Exp. Cell Res., 45: 206-217, 1967.
l
- 53. Epstein, S. S., Joshi, S., Andrea, J., Forsyth, J., and Mantel, N.:
The null effect of antioxidants on the carcinogenicity of 3,4,9,10- ~
dibenzpyrene to mice.
Life Sci., 6,: 225-233, 1967.
- 54. Epstein, S. S. and Niskanen, E. E.:
Effects of Tween 60 on benzo (a) pyrene uptake by Tetrahymena pyriformis and by isolated rat liver mitochondria.
Exp. Cell Res., 46: 211-234, 1967.
- 55. Epstein, S. S., Joshi, S., Andrea, J. , Clapp, P. , Falk, H. , and Mantel, N. :
The synergistic toxicity and carcinogenicity of Freons and piperouyl butoxide.
Nature, 214: 526-528, 1967.
- 56. Epstein, S. S., Saporoschetz, I. B., and Hutner, S. H.: -
Cytotoxicity of antioxidants to Tetrahymena pyriformis.
J. Protozool., 14: 238-244, 1967.
- 57. Nagata, C., Fujii, K., and Epstein, S. S.:
Photodynamic activity of 4-nitroquinoline-1-oxide and related compounds.
Nature, 215: 972-973, 1967. .
~r' 12 PUBLICATIONS (cont.)
- 58. Epstein, S. S., Andrea, J., Joshi, S., and Mantel, N.:
Hepatocarcinogenicity of griseofulvin following parenteral administration to infant nice.
Cancer Res., 27: 1900-1906, 1967.
- 59. Epstein, S. S., Andrea, J., Mantel, N., and Falk, H.:
Carcinogenicity of the herbicide maleic hydrazide.
Nature, 215: 1388-1390, 1967.
- 60. Epstein, S. S.:
Carcinogenicity of organic extracts of atmospheric pollutants.
J. Air Poll. Control Assoc., 17, 728-729, 1967.
- 61. Epstein, S. S., Andrea, J., Clapp, P., and Mackintosh, D.:
Enhancement by piperonyl butoxide of acute toxicity due to Freons, tenzo(a) pyrene, and 9riseofulvin in infant mice.
Toxicol. Appl..Pharmacolo., 11,, 442-448, 1967.
- 62. McCarthy, R. E., and Epstein, S. S.:
Cytochemical and cytogenetic effects of maleic hydrazide on cultured mammalian cells.
Life Sci., 7,, 1-6, 1968.
- 63. Epstein, S. S., Mantel, N., and Stanley, T. W.:
Photodynamic assay of neutral sub-fractions of organic extracts of particulate atmospheric pollutants.
Env. Sci. Tech., 2,, 132-141, 1968.
- 64. Epstein, S. S. and Mantel, N.:
Hepatocarcinogenicity of maleic hydrazide following parenteral administration to infant Swiss mice.
- Internat. J. Cancer, 3,, 325-335, 1968.
- 65. Rondia, D. and Epstein, S. S.:
The effect of antioxidants on photodecomposition of benzo (a) pyrene.
Life Sci., 7,, 513-518, 1968.
- 66. Epstein, S. S.:
Carcinogenicity of Tetraethyl lead.
Experientia, 24, 580, 1968.
- 67. Epstein, S. S. and Shafner, H.:
Use of mammals in a practical screening test for chemical mutagens in the human environment.
Nature, 219, 385-387, 1968.
l
- 68. Ja f f e , J. , Fuj ii , K. , Sengupta,'M., Guerin, H., and Epstein, S. S.:
In vivo inhibition of mouse liver microsomal hydroxylating systems by methylenedioxyphenyl insecticidal synergists and related compounds.
Life Sci., 7, 1051-1062, 1968.
- l 13 PUBLICATIONS (cont.)
- 69. Epstein, S. S.:
Cancer and mutation-producing chemicals in polluted urban air.
Air Pollution (Air Quality Criteria) Hearings before the Sub-committee on Air and Water Pollution of the Committee on Public Works.
U. S. Senate, 90th. Crongress. Washington, D.C., 1968, Chairman, Senator Edmund S. Muskie.
- 70. Epstein, S. S.:
Irradiated Foods Sicence, 161, 739, 1968.
- 71. Fujii, K., Jaffee, H., and Epstein, S. S.:
Factors influencing the hexobarbital sleeping time and zoxazolamine paralysis time in mice.'
Toxicol . Appl . Pha rmacol . , 13, 431-438, 1968.
- 72. Epstein, S. S. and,Saporoschetz, I. B.:
On the association between lysogeny and carcinogenicity in nitroquinolines.
Experientia, 24, 1245-58, 1968
- 73. Jaffe, H., Fujii, K., Sengupta, M., Guerin, H., and Epstein, S. S.:
the bi-modal effect of piperonyl butoxide on o- and p-hydroxylation of biphenyl by mouse liver microsomes.
Biochem. Pharmacol., 18, 1045-1051, 1969.
- 74. Epstein, S. S.:
Chemical mutagens and the Environmental. Mutagen Society
" Current Opinion" editorial Medical Tribune and Medical News, 10, pp 11-15, June 2, 1969.
- 75. Pagnatto, L. D., and Epstein, S. S.:
The ef fects of antioxidants on ozone toxicity in mice.
Experientia, 25, 703-704, 1969.
- 76. Epstein, S. S.:
A catch-all toxicological screen.
Experientia, 25, 617-618, 1969.
- 77. Epstein, S. S., and St. Pierre, J. A.:
Mutagenicity in yeast of nitroquinolines and related compounds.
Toxicol. Appl. Pharmacol., M , 451-460, 1969.
- 78. Epstein, S. S.: -
Introduction to symposia on toxicologic and epidemiologic basen for air quality criteria.
J. Air Pollution Control Assoc., 19, 629-630, 1969.
- 79. Upstein, S. S.:
Chemical hazards in the human environment.
Ca-A Cancer Journal for Clinicians, 19, 277-281, 1969.
14 PUBLICATIONS (cont.)
- 80. Epstein, S. S.:
Biological approaches to estimation of environment hazards.
Drug Information Bulletin 3,, 150-152, 1969.
- 81. Epsteir., S. S., Hollaender, A., Lederberg, J., Legator, M., Richardson, H.
and Wilff, A. H.:
Cyc.'smate Ban Science, 166, 1575, 1969.
- 82. Lijinsky, W., and Epstein, S. S.:
Nitrosamines as environmer.tal carcinogens.
Nature, 225, 21-23, 1970.
- 83. Epstein, S. S., Fujii, K., Andrea, J., and Mantel, N.:
Carcinogenicity testing of food additives and antioxidants by parenteral administration to infant Swiss mice.
Toxicol. Appl. Pharmacol. 16,, 321-334, 1970.
- 84. Fuj ii, K. , Ja f fe, H. , Bishop, Y., Arnold, E., Mackintosh, D. , and Epstein, S.S. :
Structure-activity relations for methylenedioxyphenyl and related compounds on hepatic microsomal enzyme functions, as measured by prolongation of hexobarbital narcosis and zoxazolamine paralysis in mice.
Toxicol. Appl. Pharmacol. 16, 482-494, 1970.
- 85. Epstein, S. S., Joshi, S. R., Arnold, E., Page, E. C., and Bishop, Y.:
Abnormal zygote development in mice after paternal exposure to a chemical mutagen.
Nature 225, 1260-1261, 1970.
- 86. Epstein, S. S.: .
" Teratogenic effects of 2,4,5-T formulations". At hearings before the Subcommittee on Energy, Natural Resources and the Environment, of the Committee on Commerce. U. S. Senate, Washington, D.C.
April 15, 1970, presided by Senator Philip A. Hart.
- 87. Epstein, S. S.:
Potential hazards due to nitrates and nitrate detergents in water.
At hearings before the Subcommittee on Air and Water Pollution, of the Senate Committee on Public Works. U.S. Senate, Washington, D.C.
May 6, 1970, Chairman, Senator Edmund S. Muskie.
- 88. Epstein, S. S. and Lederberg, J.
Chronic non-psychiatric hazards of drugs of abuse.
Science 168, 507-509, 1970.
- 89. Epstein, S. S., Bass, W. , Arnold, E., and Bishop, Y.:
The mutagonicity of ^ trimethyl phosphate in mice.
Science 168, 584-586, 1970.
- 90. Malling. H. V., Wassom, J. S., and Epstein, S. S.
Mercury in our environment.
l Environmental Mutagen Society Newsletter 3, 7-9, 1970.
IS .
PUBLICATIONS (cont.) ;
- 91. Epstein, S. S., Arnold, E., Steinberg, K., Mackintosh, D., Shafner, H.,
and Bishop, Y.
Mutagenic and antifertility effects of TEPA and METEPA in mice.
Toxicol. Appl. Phannacol. 17_, 23-40, 1970.
- 92. Epstein, S. S., Bass, W., Arnold, E., and Bishop, Y.:
The failure of caffeine to induce mutagen!.c effects or to synergize the effects of known mutagens in mice.
Fd. Cosmet. Toxicol. 8,, 381-401, 1970.
- 93. Epstein, S. S.:
A family likeness: 2,4,5-T and 2,4-D.
Environment 12, 16-25, 1970. .
- 94. Epstein, S. S.:
Mutagenitatsprufung in der Tbxikologie.
Umschau, 15,, 475-476, 1970.
- 95. Epstein, S. S., Csilla3, R. G., Guerin, H., and Friedman, M. A.:
Ef fects of methylenedioxyphenyl insecticidal synergists in vitro on hydroxylations of biphenyl by mouse liver microsomes.
Biochem. Pharmacol. 19, 2605-2607, 1970.
- 96. Joshi, S. R., Page, E. C., Arnold, E., Bishop, Y., and Epstein, S. S.:
Fertilization and early embryonic development subsequent to mating with TEPA-treated male mice.
Genetics, 65, 483-494, 1970.
- 97. Epstein, S. S. and Fujii, K.:
Synergism in carcinogenesis with particular reference to synergistic effects of piperonyl butoxide and related insecticidal synergists.
Chapter, pp 21-42. In, Chemical Tumor Problems, ed. Nakahara, W. ,
Pub. Japanese Society for the Promotion of Science, Tbkyo, Japan, 1970.
- 98. Epstein, S. S.:
I. Adverse biological effects due to chemical pollutants: General Principles II. Potential carcinogenicity, mutagenicity and teratogenicity due to community air pollutants.
Appendix M. pp 1-54. Project Clean Air. Task Force Assessments. Vol. 2.
Project Clean Air, Regents of the Univ. of California, Sept. 1, 1970.
- 99. Epstein, S. S.:
The failure of caf feine to-induce mutager.ic effects or to synergize j
the effects of known mutagens in mice. Chapter 25, pp 404-419.
l In, Chemical Mutagens, ed. Vogel, P., and Rohrborn, G., Publ. Springer-Verlag, Berlin, Heidelberg, New York, 1970.
l 100. Friedman, M. and Epstein, S.S. :
- Stability of Piperonyl Butoxide.
Toxicol. Appl. Pharmacol. 1_7_, 810-812, 1970.
i in i
1 l
d
_ PUBLICATIONS (cont.)
101. Epstein, S. S.:
NTA Environment 12,, 2-11, 1970.
102. Epstein, S. S.:
Control of chemical pollutants.
Nature, 228, 816-819, 1970.
103. Epstein, S. S.:
Toxicological and environmental implications on the use of Nitrilotri-acetic acid as a detergent builder.
Staff Report. Prepared for use of the Committee on Public Works, U. S. Senate, December,,1970. .
104. Bateman, A. and Epstein, S. S.:-
Dominant lethal mutations in mamnals, Chapter in, Environmental Chemical Mutagens, ed. Hollaender, A., Plenum Publishing Co., New York, 1971.
105. Alam, B. S., Saporoschetz, I. B., and Epstein, S. S.:
Formation of N-nitrosopiperidine and sodium nitrite in the stomach and the isolated intestinal loop of the rat.
Nature, 232, 116-118, 1971.
106. Epstein, S. S.:
" Adverse Human Effects due to Chemical Pollutants". at Hearings before the Subcommittee on Executive Reorganization and Government Research, of the Committee on Government Operation, U.S. Senate Washington, D.C.,
April 6, 1971. Dhairman, Senator Abraham Ribicoff.
and Adler,'I.D.:
107. Epstein, S. S., Bass, W., Arnold, E., Bishop, Y., Joshi, S.,
Sterility and semi-sterility in male progeny of male mice treated with the chemical mutagen TEPA.
- Toxicol. Appl. Pharmacol., 19, 134-146, 1971.
Epstein, S. S., Saporoschetz, I. B., Katsioules, C.,
and Bishop, Y.:
108.
Bioassay for antioxidants based on protection of isolated rat liver mitochondria against the photodynamic toxicity of benzo (a) pyrene.
Fd. Cosmet. Toxicol. 9,, 367-377, 1971.
109. Epstein, S. S., Buu-Hoi, N. P., and Hien, Do-Phuoc:
On the association between photodynamic and enzyme-inducing activities in polycyclic compounds.
Cancer Res., 31, 1087-1094, 1971.
110. Alam, B. S., Saporoschetz, I.B. and Epstein, S. S.:
The synthesis of nitrosopiperidine from nitrate and piperidine in the stomach and small intestine and in isolated gastric contents of the rat.
Nature, 232, 199-200, 1971.
11 1
- PUBLICATIONS (cont.) .
111. Epstein, S. S. and Legator, M. (editors) :
The Mutagenicity of Pesticides, M.I.T. Press, Cambridge, Massachusetts and Longon, England, 1971.
112. Epstein, S. S. and R5hrborn, G.:
Recommended procedures for testing genetic hazards due to chemicals, based on the induction of dominant lethal mutations in mammals.
Nature, 230, 459-460, 1971.
113. Epstein, S. S., Friedman, M. A. and McCaull, J. :
Eye on our Defenses.
Environment, 13,, 43-47, 1971.
114. Friedman, M. A., Millar,'G., McEvoy, A., and Epstein, S. S.:
Rapid and simplified method for liquid scintillation counting of radioactive proteins utilizing aguasol.
Anal. Chem., 43, 780, 1971.
115. Epstein, S. S.(editor):
Drugs of Abuse -- Genetic and other chronic Non-Psychiatric Hazards.
M.I.T. Press, Cambridge, Massachusetts, and London, England,1971.
116. Bishop, Y., Fujii, K., Arnold, E., and Epstein, S. S.: ,
Censored distribution technique in analysis of toxicological data.
Experientia. 27,, 1056-1059, 1971.
117. Asahina, S., Friedman, M., Arnold, E., Miller, G., Mishkin, M., and Epstein, S. S.:
Acute synergistic toxicity and hepatic necrosis following oral administration of sodium nitrite and secondary amines to mice.
Cancer Res., 31,: 1201-1205, 1971.
118. Friedman, M. A., Sengupta, M., Arnold, E., Bishop, Y., and Epstein, S. S.:
Additive and synergistic inhibition of mammalian microsomal enzyme functions by piperonyl butoxide', safrole and other methylenedioxyphenyl derivatives.
Experientia. 2j[, 1052-1054, 1971.
119. Adler, I. D., Ramarao, G. and Epstein, S. S.:
In vivo cytogenetic effects of trimethylphosphate and of TEPA on bone marrow cells of male rats.
Mutation Res. , 13, 263-273, 1971.
120.
Epstein, S. S.:
Environmental Pathology, A Review.
Am. J. Path. 66,, 352-374, 1972.
121. Friedman, M. A., Sengupta, M. and Epstein, S. S.:
Paradoxical effects of piperonyl butoxide on the kinetics of mouse liver microsomal enzyme activity.
'Ibxicol. Appl. Phamacol. 21_, 419-427, 1972.
[
]
I I
In .
i PUBLICATIONS (cont.)
122. Epstein, S. S.:
Information requirements for determining the benefit-risk spectrum.
In, perspectives on benefit-risk decision making. pp. 50-62.
Committee on Public Engineering Policy, National Academy of Engineering, Washington, D.C., 1972.
123: Epstein, S. S.:
Identification of hazards in the environment: Introductory remarks In, Environment and Cancer, pp. 56-68.
Williams and Wilkins Pub. Co., Baltimore, 1972.
124. Friedman, M. A., Millar, G., Sengupta, M'. and Epstein, S. S.:
Inhibition of mouse liver protein and nuclear RNA synthesis following' combined oral treatment with sodium nitrite and dimethylamine or methylamine or methylbenzylamine.
Experientia, 2 8,, 2-22, 1972.
125. Epstein, S. S.:
Toxicological and Environmental Implications on the use of nitrilotri-acetic acid as a detergent builder - I.
Int. J. Environ. Studies, 2,, 291-300, 1972.
126. Epstein, S. S.:
Toxicological and Environmental Implications on the use of nitrilotri-acetic as a detergent builder - II.
Int. J. Environ. Studies, 3,, 13-21, 1972.
127. Epstein, S. S.:
"The Delaney Amendment and on Mechanisms for Reducing Constraints in the Regulatory process, in General, and as applied to Food Additives in particular." At hearings before the Select Committee on Nutrition and Human Needs. U.S. Senate, Washington, D.C. September 20, 1972.
128. Friedman, M. A., Green, E. J., and Epstein, S. S.:
Rapid gastric absorption of sodium nitrite in mice.
J. Pharm. Sci., 61,: 1492-1494, 1972.
129. Epstein, S. S., Arnold, E., Andrea, J., Bass, W., and Bishop, Y.:
Detection of chemical mutagens by the dominant lethal assay in the mouse.
Toxicol . Appl . Pha rmacol . , 23 : 288-325, 1972.
130. Asahina, S., Andrea, J., Carmel, A., Arnold, E., Bishop, Y., Joshi, S.,
Coffin, D. and Epstein, S. S.:
Carcinogenicity of organic fractions of particulate atmospheric pollutants in New York City following parenteral administration to infant mice.
Cancer Research, 32, 2263-2268, 1972.
I 131. Epste*in, S. S.:
Teratological llazards Due to Phenoxy Herbicides and Dioxin Contaminants.
Chap. 12, pp. 708-729. In. Pollution: Engineering and Scientific Solutions, ed., Barrekette, E. S., Publ. Plenum Publ. Co., New York, 1972.
I 19 PUBLICATIONS (cont.) ;
132. Epstein, S. S.:
In vivo Studies on Interactions between Secondary Amines and Nitrites or Nitrates. pp. 109-115. In, N-Nitroso Compounds. Analysis and Formation. International Agency for Research on Cancer, Lyon, France.
Scientific Publication No. 3, 1972.
133. Friedman, M. A., Millar, G. N., and Epstein, S. S.:
Acute dose-dependent inhibition of liver nuclear RNA synthesis and methylation of guanine following oral administration of sodium nitrite and dimethylamine to mice. Int. J. Environ. Studies. 4, 219-222, 1973.
134. Lavappa , K. S., Fu, M. M., Sing, M., Beyer, R. D., and Epstein, S. S.:
Banding patterns of chromosomes in bone marrow cells of the Chinese hamster as revealed by acetic-saline-Giemsa, urea and trypsin techniques.
Lab. Animal Sci. , 2 3,, 546-550, 1973.
135. Lavappa', K. S., Yerganian, G. and Epstein, S. S.:
Autosomal heteromorphism in the Armenian hamster.
Genetics, 74: S151, 1973.
136. Epstein, S. S.:
"The Federal Food and Inspection Act of 1973 and on Deficiencies in Current Procedures for Monitoring Animal Food for Carcinogenic and Toxic Residues of Animal Drugs." Testimony before the Committee on Commerce, U.S. Senate, March 21, 1973.
137. Epstein, S. S.: .
The Delaney Amendment Ecologist, 3_, 420-431, 1973.
138. Epstein, S. S.:
The Delaney Amendment Preventive Med., 2,, 140-149, 1973.
139. Epstein, S. S.:
Environment and Teratogenesis Chapter 8g pp. 105-113. In, Pathobiology of Development. Eds. Perrin, E.V.
and Finegold, M. J., Publ. Williams and Wilkins Co. , Baltimore,1973.
140. Epstein, S. S.:
Mutagenicity associated with air pollutants.
pp. 585-602, Proceedings of the Conference on Health Aspects of Air Pollution, NAS-NRC. Oct. 3-5, 1973. Committee Print. Senate Committee on Public Works, Ser. No. 93-15, U.S. GPO, Washington, D.C., Nov. 1973.
141. Joshi, S. R., Bishop, Y. and Epstein, S. S.:
Reduced fertility in mice following treatment with Niridazole.
Experientia, 29, 1253-1255, 1973.
142. Epstein, S. S.:
Use of the Dominant Lethal Test to detect genetic activity of environmental chemicals. Environ. Health Perspec., 6, 23-26, 1973.
20 PUBLICATIONS (cont.)
143. Fine, D. H., Rufeh, F., Lieb, D. and Epstein, S. S.:
A possible nitrogen oxide-nitrosamine cancer link.
Bull. Environ. Contam. Toxicol., 11: 18-19, 1974.
144. Epstein, S. S.:
Definition of Risk: Priority for Safety, pp. 241-248, In, Environmental Quality and Food Supply. Ed., White, P.L. Futura Publ. Co., Inc.,
1974.
145. Epstein, S. S.:,
Chronic biological hazards due to chemicals. In, Birth Defects and Fetal Development. Chapter 9, pp. 136-166. Ed. Moghissi, H.,
C. C. Thomas. Publ., Springfield, Ill., 1974.
146. Alarif, A. and Epstein, S. S.: 14 Chemical synthesis of methyl C and H3 1abeled N-methylnitrosourethane J. Labeled Comp., g , 161-164, 1974.
147. Epstein, S. S.:
Introductory Remarks to Sessions on " Mutagens in the Biosphere".
First International Conference on Environmental Mutagens. Asilomar, Calif.,
August 28, 1973, Mutation Res., 26, 219-223, 1974.
148. Epstein, S. S.:
" Current problems with occupational health standards." Testimony before the House Select Subcommittee on Labor, Committee on Education and Labor, April 25, 1974.
149. Epstein, S. S. and Grundy, D. (editors) :
The legislation of Product Safety. Consumer Health and Product Hazards.
Vol. I, Chemicals, Electronic Products,. Radiation. MIT Press, Cambridge, Mass. and London, England, 1974.
150. Epstein, S. S. and Grundy, D. (editors) :
The Legislation of Product Safety: Consumer Health and Product Hazards.
MIT Press, Vol II. Cosmetics and Drugs, Pesticides, Food Additives.
151. Epstein, S. S.:
The carcinogenicity of Dieldrin. Testimonies at hearings on Aldrin /
Dieldrin, Environmental Protection Agency and Environmental Defense Fund vs Shell. Cancellation Hearings, March, 1974: Suspension Hearings, Sept. 1974.
152. Epstein, S. S.:
Policy options for reducing public health hazards from combustion of '
leaded gasoline, Part 2. Hearings before the Panel on Environmental Science and Technology of the Subcommittee on Environmental Pollution of the Committee on Public Works. U.S. Senate, 93rd. Congress, May 7-8, 1974.
153. Epstein, S. S.:
Environmental determinants of human cancer.
Cancer Res. 34: 2425-2435, 1974.
[ ]
21 4
i PUBLICATIONS (cont.)
154. Epstein, S. S.:
Multiple factors in carcinogenesis.
Ehviron. Health Perspec., 9, 331-333, 1974.
155. Amacher, D. D., Alarif, A. and Epstein, S. S.:
The effects of ingested chrysotile on DNA synthesis in the gastrointestinal tract and liver of the rat.
Environ. Health Perspec. 9, 319-324, 1974.
J 156. Alarif, A. and Epstein, S. S.:14 The uptake and metabolism of C-labeled Nitrosomethylurethane and methylnitrosourea in guinea pigs and their in, vitro metabolism in the guinea pig and human pancreas.
International Agency for Research of Cancer. Lyon, France, 215-219, 1974.
157. Billmaier, D., Yee, T., Allen, N., Craft, R., Williams, N., Fontaine, R.,
and Epstein, S. S.:
Peripheral neuropathy in a coated fabrics P lant.
J. Occupational Medicine 16,, 655-671, 1974.
158. Epstein, S. S. and Hattis, D.:
Regulatory aspects of occupational carcinogens.
Proceedings XI International Cancer Congress. Florence, October 20-26, 1974.
In Vol. 3, Cancer Epidemiology, Environmental Factors,1974.
159. Epstein, S. S.:
Carcinogens in industry: needed studies.
In, the New Multinational Health Hazards, pp. 172-188, Proceedings of the ICF International Occupational Health Conference, Geneva, Octover 20-30, 1974. ,
, 160. Legator, M. S. and Epstein, S. S.:
Testing for chemically-induced mutations.
Chapter 9, Environmental Problems on Medicine, Editor, McKee, .
Published C. C. Thomas, Springfield, Illinois, 1974.
161. Epstein, S. S. and Hattis, D.:
Adverse health effects and chemical pollutants of the environ =ent.
Chapter 8. In Environment: Resources, Pollution and Society, 2nd. edition.
Editor, Murdoch, W. N., Publisher, Sinauer Associates,1975.
162. Epstein, S. S.:
Impact of mobile emissions control. The public interest overview.
Conference on Health Consequences of Environmental Controls.
Environmental Health Perspectives 10, 173-179, 1975.
163. Hasumi, K., Iqbal, Z. M., Alarif, A., and Epstein, S. S.:
DNA repair synthesis following exposure of guinea pig pancreatic slices to methyl-N-nitrosourethane in vitro.
Experientia, 31, 467, 1975.
164. Epstein, S. S.:
The carcinogenicity of dieldrin. I.
! The Science of the Total Environment, 4, 1-52, 1975.
l
22 PUBLICATIONS (cont.)
165. Epstein, S. S.
The carcinogenicity of dieldrin. II.
The Science of the Total Environment, 4, 205-217, 197b.
166. Fine, D. H., Rounbehler, D. P., Huffman, F., and Epstein, S. S.:
Analysis of volatile N-nitroso compounds in drinking water at the part per trillion level.
Bull. Environ. Contam. Toxicol. 14, 404-408, 1975.
167. Hasumi, K., Wilber, J. H., Berkowitz, J., Wilber, R. G., and Epstein, S. S.:
Pre and post-natal toxicity induced in guinea pigs by N-nitrosomethyl urea.
Teratology. 12,, 105-110, 1975.
168. Fine, D. H., Rounbehler, D. P., Belcher, N. M., and Epstein, S. S.:
N-Nitroso Compounds in the Environment.
International Conference on Environmental Sensing and Assessment.
Las Vegas, September 14-19, 1975.
169. Amacher, D. E., Alarif, A., and Epstein, S. S.:
The Dose-dependent 'ef fect of ingested chrysotile on DNA synthesis in the gastro-intestinal tract, liver and pancreas of the rat.
Environ. Res. ---10, 208-216, 1975.
170. Lavappa, K. S., Fu, M. M., and Epstein, S. S.:
Cytogenetic studies on chrysotile asbestos.
Environ. Res. 10, 165-173, 1975.
171. Page. T., Harris, R. H., and Epstein, S. S.
Drinking water and cancer mortality in Louisiana.
Science, 193, 55-57, 1976.
172. Hasumi, K., Iqbal, Z. M., and Epstein, S. S.:
DNA repair synthesis in guinea pig slices following in vitro exposure to nitrosomethylurethane.
Chem.-Biol. Interactions, 13,, 279-286, 1976, 173. Epstein, S. S. and Varnes, M.:
The short-term effects of ingested chrysotile asbestos on DNA synthesis in the pancreas and other organs of a primate.
Experientia, 32,, 602-604.
174. Fine, D. H., Rounbehler, D. P., Belcher, N. M., and Epstein, S. S.
N-nitroso compounds: Detection in ambient air.
Science, 192, 1328-1330, 1976.
175. Epstein, S. S.:
Potential carcinogenic hazards due to contaminated drinking water.
Proceedings of the International Conference on Biological Control of Water Pollution, 00 73-84, Editors, Tourbier, J. and Pierson, R.W., University of Pennsylvania Press, 1976.
23 PUBLICATIONS (continued) t 176. Iqbal, Z. M., Majdan, M. and Epstein, S. S.:
Evidence of repair of DNA damage induced by 4-hydroxyaminoquinoline-1-oxide in guinea pig pancreatic slices in vitro.
Cancer Res., 36,, 1108-1113, 1976.
177. Epstein, S. S.:
Aldrin and dieldrin - Suspension based on environmental evidence and evaluation of societal needs.
Conference on Occuaptional Carcinogenesis, March 24, 1976.
New York Academy of Sciences, 271, 187-195, 1976.
178. Epstein, S. S.:
The political and economic basis of cancer.
' Technology Review, 3,34-43,1976.
f' 179. Iqbal, Z. M. and Epstein, S. S.:
Effects of N-methyl-N-nitrosourethane on DNA synthesis in the guinea pig pancreas.
Chem.-Biol. Interactions,15, 131-137, 1976.
180. Epstein, S. S. : .
The carcinogenicity of heptachlor and chlordane The Science of the Total Environment, 6,, 103-154, 1976.
181. Iqbal, Z. M. and Epstein, S. S.:
Kinetics of DNA repair synthesis in guinea pig pancreatic slices following in vitro exposure to N-methyl-N-nitrosourethane.
Experientia 32: 1055-1056, 1976.
182. Iqbal, Z.M. and Epstein, S. S.:
DNA repair synthesis in guinea pig pancreas following exposure to nitrosomethyl urethane.
International Agency for Cancer Research, WHO, Publication No.141, pp. 411-424, Lyon, France, 1976.
183. Epstein, S. S., Hasumi, K. and Iqbal, Z.M.:
Pre-natal and post-natal toxicity induced in guinea pigs by nitroso-methylurea.
International Agency for Cancer Research, WHO, Publication No.14, pp. 435-442, Lyon, France, 1976.
184. Fine, D. H., Rounbehler, D. P., Belcher, N. M. and Epstein, S. S.:
N-nitroso compounds in air and water.
International Agency for Cancer Research, WHO, Publication No. 14, pp. 401-408, Lyon, France, 1976.
185. Epstein, S. S.:
Developing health policies and standards; Responsibility of the scien-tist in developing and interpreting "Public Interest" viewpoints. LASL Third Life Sciences Symposium, Los Alamos, New Mexico, October 15-17, 1975, pp. 42-50 in " Impact of Energy Production in Human Health, eds.
E.C. Anderson and E.M. Sullivan, Energy Res and Development Adm. , 1976.
24
(
PUBLICATIONS (Cont.)
186. Gage, K. and Epstein, S. S.:
The federal advisory committee system.
Environmental Law Reporter, 7,, 50001-50012, 1977.
187. Epstein,'S. S.:
Viewpoints: The han that may save your life.
Newsday, Friday, March 25, 1977.
188. Epstein, S. S.:
Cancer and the environmant.
Bull. Atomic Scientists, 33,(3), 22-30, 1977.
189. Iqbal, Z. M., Varnes, M.E., Yoshida, A., and Epstein, S. S.:
Metabolism of benzo (a) pyrene by guinea pig pancreatic microsomes.
Cancer Res. 37,, 1011-1015, 1977.
190. Epstein, S. S.:
AFL-CIO proposed OSHA lead standard: Its biological and environmental bases.
Testimony at Department of Labor Hearings, March 21, 1977.
191. Fine, D. H., Rounbehler, D. P., Ross, R., Song, L., Silve,rgleid, A.,
Iqbal, Z. M., and Epstein, S. S.:
Quantitation of dimethylnitrosamine in the whole mouse following biosynthesis from trace levels of precursors.
Science, 197, 917-918, 1977.
192. Epstein, S. S.:
The case for a consumer protection agency.
Bull. Atomic Scientist,33,(7), 6-7, 1977.
193. Epstein, S. S. and Andrea, J. and Bishop, Y.:
Protection by antioxidants against the toxicity of ozone to microbial
! systems.
Environmental Research, 14_, 187-193, 1977.
194. Yoshida, A. Iqbal, Z. M., and Epstein, S. S.:
Hepatocarcinogenic effects of N-methyl-N-nitrosourea in guinea pigs.
j Cancer Research, 37,, 4043-4048, 1977.
195. Epstein, S. S.:
The carcinogenicity of organochlorine pesticides.
pp. 243-265, In " Origins of Human Cancer", eds. H. H. Hiatt, J.D. Watson and J.A. Winsten, Cold Spring Harbor Laboratory,1977.
f .
196. Epstein, S. S.:
Kepone - hazard evaluation.
The Science of the Total Environment, 9, 1-62, 1978.
J
25 PUBLICATIONS (Cont.)
\
197. Iqbal, Z. M. and Epstein, S. S.:
Evidence of DNA repair in the guinea pig pancreas in vivo and in vitro, following exposure to N-methyl-N-Nitrosourethane.
Chem.-Biol. Interactions, 20[, 77-87, 1978.
198. Epstein, S. S.:
Testimony before the Department of Labor, Occupational Safety and Health Administration, on Regulation of Toxic Substances Posing a Potential Occupational Carcinogenic Risk to Humans.
(OSHA Docket No. 090) , April 4,1978.
199, Epstein, S. S.:
Testimony before the Environmental Protection Agency on the Proposed Regulation of Chemical Carcinogens in Drinking Water, July 11, 1978.
200. Epstein, S. S.:
Polluted Data.
The Sciences, 18_, 16-21, 1978.
201. Infante, ' P. F. , Newton, W. A. and Epstein, S. S . :
Blood dyscrasias and childhood tumors following exposure to chlori-nated hydrocarbon pesticides.
Scand. J. Work Environment, 4,, 137-150,1978 202. Epstein, S. S.:
The Politics of Cancer.
Sierra Club Books, San Francisco, 1978.
203. Epstein, S. S.:
Testimony before the California Health Assembly Committee on "The Inflationary Impact of Failure to Regulate with Particular Reference to Cancer, August 8, 1979.
204. Epstein, S. S.:
The Politics of Cancer. (Revised and expanded edition)
Anchor /Doubleday Press, New York, 1979.
205. Epstein, S. S., Fujii, K., and Asahina, S.:
Carcinogenicity of a composite organic extract of urban particulate atmospheric pollutants following subcutaneous injection in infant mice.
Environmental Res. 19,, 163-176, 1979.
206. Fujii, S.,-and Epstein, S. S.:
Effects of piperonyl butoxide on the toxicity and hepatocarcinogeni-city of 2-acetylaminofluorene and 4-acetylaminobiphenyl, and their N-hydroxylated derivatives, following administration to newborn mice.
Oncology 36, 105-112, 1979.
207. Iqbal, Z. M., Yoshida, A., and Epstein, S. S.:
Uptake and excretion of benzo (a) pyrene and its metabolites by the rat pancreas.
Drug Metabolism and Disposition. 7,, 44-48, 1979.
y 26 4
PUBLICATIONS (Con't) i 208. Yoshida, A., Iqbal, Z. M., and Epstein, S. S .' s Spontaneous pancreatic islet cell tumors in guinea pigs.
J. Comp. Pathol. 89, 471-400, 1979.
209. Epstein, S. S.: ,
Cancer and Inflation.
The Ecologist, 9, 236-246, October-November, 1979.
210. Epstein, S. S.:
Polluted Data The Ecologist, 9, 264-268, November-December, 1979.
i 211. Epstein, S. S.:
The Polluters Hit Back The Ecologist, 9, 269-272, November-Dec6aber, 1979.
212. Epstein, S. S.:
Information Requirements of the Public.
American Industrial Health Association Journal,48-54, December, 1979.
213. Epstein, S. S.:
Cancer, Inflation and the Failure to Regulate
~
Technology Review, 82, 42-53, 1979.
~
214. Epstein, S. S.:
Testimony on " White Collar Crime" Before the Subcommittee on Crime on the ,
Committee on the Judiciary, U.S. House of Representatives, December 13, 1979.
215. Iqbal, Z. M., Dahl, K., and Epstein, S. S.: -
Role of Nitrogen Dioxide in the Biosynthesis of Nitrosamines in Mice '
Science 207, 1475-1477, 1980.
216. Whalley, C. E., Iqbal, Z. M., and Epstein, S. S.:
The Separation of N-nitroso-di-n-propylamine and its B-oxidized Carcinogenic Metabolites by High Pressure Liquid Chromatography, J. Liquid Chromat. 3,(5) , 693-703, 1980.
217. Epstein, S. S.: ~+
" Testimony on Agent orange and H.R. 6377" Before the House Subcommittee on Medical Facilities and Benefits, Committee on Veteran Affairs, U.S. House of Representatives, July 22, 1980.
218. Epstein, S. S.: N "A Citizen's Guide to New Perspectives in Hazardous Waste Reduction,"
Testiraony Before Governor Brown's Hearing Panel on Hazardous Waste -
, Disposal, Los Angeles, Califorr'_a, November 18, 1980.
219. Epstein, S. S. and Swartz, J.
Fallacies of Lifestyle Cancer Theories Nature 289, 127-130, 1981.
s __. ._- _ -
F-27 .
PUBLICATIONS (cont) 220. Whalley, C.E., Iqbal, Z.M. and Epstein, S.S.:
In Vivo and Microsomal Metabolism of the Pancreatic Carcinogen UTUitrosobis(2-oxopropyl) amine by the Syrian Golden Hamster.
Cancer Research 41, 482-486, 1981.
221. Iqbal, Z.M. and Epstein, S.F. , et, al . :
Kinetics of Nitrosamine Formation in Mice Following Oral Administration of Trace-Level Precursors.
International Agency for Research on Cancer (IARC), Proceeding of VIth International Symposium on N-Nitroso Compounds, Budapest, October 16-20, 1979, pp. 169-182, IARC Scientific Publication No. 31, Lyon, France, 1980.
222. Epstein, S.S., Iqbal, Z.M. and Johnson, M.D.:
In Vivo Nitrosation of Morpholine in Mice by Inhaled NO 2.
International Agency for Research on Cancer (IARC), Proceeding of VIth International Symposium on N-Nitroso Compounds, Budapest, October 16-20, 1979, pp. 195-206, IARC Scientific Publication No. 31, Lyon, France, 1980.
223. Epstein, S.S.:
The Role of the Scientist in Toxic Tort Case Preparation.
Trial 17_(7) : 38, 1981.
224. Iqbal, Z.M. and Epstein, S.S.:
In Vivo Hitrosation of Amines by Inhaled Nitrogen Dioxide and Inhalation of the Biosynthesis of Nitrosamines.
International Agency for Research in Cancer (IARC), Proceedings of VIIth International Symposium on N-Nitroso Compounds, Tokyo, Japan, September 28-October 1, 1981.
225. Epstein, S.S.:
Focus on Food Safety: Evaluating Risk Heasurementa.
Proceedings Fourth National Food Policy Conference. Community Nutrition Institute and Food Marketing Institute, pp 48-57, Washington, D.C.,
April 7, 1981.
226. Iqbal, Z.M., Dahl, K., and Epstein, S.S.:
Biosynthesis of Dimethylnitrosamine in Dimethylamine-treated Mice After Exposure to Nitrogen Dioxide.
J. Nat. Cancer Inst. 67: 137-141, 1981.
227. Epstein, S.S.:
Surviving in the Petrochemical Age: Social and Economic Pressures Needed to Improve Toxic Waste Disposal.
Journal of Alternative Human Services. 7:(5) 18-24, 1981, 228. Epstein, S.S.:
It Costs Us All More Not to Regulate In These Times. p. 16-17, August 12-25, 1981.
Y
2d ,
, PUBLICATIONS IN PRESS f
- 1. Iqbal, Z.M. and Epstein, S.S.:
In vivo repair of DNA damage in the guinea pig pancreas following 4-hydroxyaminoquinoline-1-oxide caministration.
2.
Epstein, S.S.:
"The Price We Pay for Progress: The Hazards of the Halogenated Hydrocarbons."
Proceedings International Conference, " Chemistry-Man-Environment:
Italogenated Hydrocarbons," Gottlieb Duttweiler Institute, Zurich, Switzerland, October 13-15, 1980.
l
- 3. Epstein, S.S.:
"The Politics of Cancer: 'The Costs of Failure to Regulate"
. Proceedings of the Warner-Lambert Science and Public Policy Colloquium, The University of Michigan, Collegiate Institute for Values and Science, November 1-2, 1980.
- 4. Swartz, J.B. , Riddiough, C.R. , and Epstein, S.S. :
Analyses of Carcinogenesis Dose Response Relations Using Dichotomous Data: Implications for Carcinogenic Risk Assessment.
O
}
paw t,uratr41%WCC UNITED STATES OF AMERICA NUCLEAR REGULATORY COMMISSION BEFORE TiiE ATOMIC SAFETY & LICENSING BOARD In the Matter of I'? Cl19 P135 LOUISIANA POWER & LIGilT COMPANY Docket No. 50-382 (Waterford Steam Electric Station Unit 3)
CERTIFICATE OF SERVICE The undersigned, as counsel for Joint Intervenors, Oystershell Alliance, Inc. and Save Our Wetlands, Inc., herewith files the sworn testimony of Dr. Velma Campbell, Dr. Carl Johnson and Dr.11. Pandit, with relevant attachments and curricula vitae; and further files the sworn statements of Dr. Irwin D. J. Bross and Dr. Samuel Epstein.
The undersigned further certifies that those parties whose names appeitr on the service list followed by n asterisk (*) have been serled copics by express mail on this 8th da of March,198 l
L t IJMA L. JONES, J R.
u l SERVICE LIST j
Sheldon J. Wolfe, Esquire
- I U.S. Nucicar Regulatory Commission Atomic Safety and Licensing Board Panel
- Washington, D. C. 20555 Dr. liarry Foreman
Dr. Walter 11. Jordan
- 1 831 West Outer Drive
{ Oak Ridge, Tennessee 37830 Chairman, Atomic Safety and Licensing Board Panel U.S. Nuclear Regulatory Commission j Washington, D. C. 20555 Chairman, Atomic Safety and Licensing Appeal Board U.S. Nuclear Regulatory Commission Washington, D. C. 20555 Docketing and Service Section (three copies)
- Office of the Secretary j U.S. Nuclear Regulatory Commission ,
, Washington, D. C. 20555 Sherwin E. Turk, Esquire
- Office of Executive Legal Director
, U.S. Nuclear Regulatory Commission l Washington, D. C. 20555 1
George F. Trowbridge, Esquire and *
- E. Blake, Esquire i
Shaw, Pittman, Potts & Trowbridge 1800 M Street, N. W.
{ Washington, D. C. 20036 t
t _ . - - - . - . - - .-
- - - - -