Acceptable, Concepts, Models, Equations, and Assumptions for a Bioassay ProgramML13064A086 |
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09/30/1973 |
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US Atomic Energy Commission (AEC) |
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RG-08.009 |
Download: ML13064A086 (2) |
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Category:Regulatory Guide
MONTHYEARRegulatory Guide 1.911975-01-31031 January 1975 Evaluation of Explosions Postulated to Occur on Transportation Routes Near Nuclear Power Plant Sites. Regulatory Guide 4.91974-12-31031 December 1974 Preparation of Environmental Reports for Commercial Uranium Enrichment Facilities Regulatory Guide 3.241974-12-31031 December 1974 Guidance on the License Application, Siting, Design, and Plant Protection for an Independent Spent Fuel Storage Installation Regulatory Guide 5.401974-12-31031 December 1974 Methods for the Accountability of Plutonium Dioxide Powder ML1122304881974-12-16016 December 1974 Request for Plans for Submitting Application for a License Amendment Regarding NRC Objective to Convert Existing Licenses to Incorporate the Generalizee Provision to Reduce the Number of Licensing Actions Regulatory Guide 3.231974-11-30030 November 1974 Stabilization of Uranium-Thorium Milling Waste Retention Systems Regulatory Guide 4.71974-09-30030 September 1974 Draft General Site Suitability Criteria for Nuclear Power Stations Regulatory Guide 6.21974-07-31031 July 1974 Integrity and Test Specification for Selected Brachytherapy Sources Regulatory Guide 5.351974-06-30030 June 1974 Calorimetric Assay of Plutonium Regulatory Guide 1.861974-06-30030 June 1974 Termination of Operating Licenses for Nuclear Reactors Regulatory Guide 1.801974-06-30030 June 1974 Preoperational Testing of Instrument Air Systems Regulatory Guide 1.851974-06-30030 June 1974 Code Case Acceptability ASME Section III Materials ML0208804451974-06-17017 June 1974 License Amendment 4, Changes in Byproduct Materials Regulatory Guide 6.41974-03-31031 March 1974 Classification of Containment Properties of Sealed Radioactive Sources Contained in Certain Devices to Be Distributed for Use Under General License Regulatory Guide 1.421974-03-31031 March 1974 Interim Licensing Policy as Low as Practicable for Gaseous Radioiodine Releases from Light-Water-cooled Nuclear Power Reactors. Regulatory Guide 1.741974-02-28028 February 1974 Quality Assurance Terms and Definitions Regulatory Guide 6.11974-02-28028 February 1974 Leak Testing Radioactive Brachytherapy Sources Regulatory Guide 5.191974-01-31031 January 1974 Methods for the Accountability of Plutonium Nitrate Solutions Regulatory Guide 1.661973-10-31031 October 1973 Nondestructive Examination of Tubular Products Regulatory Guide 1.631973-10-31031 October 1973 Electric Penetration Assemblies in Containment Structures for Water-Cooled Nuclear Power Plants Regulatory Guide 1.671973-10-31031 October 1973 Installation of Overpressure Protection Devices Regulatory Guide 1.161973-10-31031 October 1973 Reporting of Operating Information Regulatory Guide 4.31973-09-30030 September 1973 Measurements of Radionuclides in the Environment Analysis of I-131 in Milk Regulatory Guide 8.91973-09-30030 September 1973 Acceptable, Concepts, Models, Equations, and Assumptions for a Bioassay Program Regulatory Guide 1.591973-08-31031 August 1973 Design Basis Floods for Nuclear Power Plants Regulatory Guide 3.111973-06-30030 June 1973 Design Stability of Embankment Retention Systems for Uranium Mills Regulatory Guide 3.91973-06-30030 June 1973 Concrete Radiation Shields Regulatory Guide 1.511973-05-31031 May 1973 Inservice Inspection of ASME Code Class 2 and 3 Nuclear Power Plant Components Regulatory Guide 1.461973-05-31031 May 1973 Protection Against Pipe Whip Inside Containment. Regulatory Guide 5.61973-05-31031 May 1973 Standard Methods for Chemical, Mass Spectrometric, and Spectrochemcial Analysis of Nuclear-Grade Plutomium Dioxide Powders and Pellets and Nuclear-Grade Mixed Oxides ((U,Pu)O2) Regulatory Guide 1.491973-05-31031 May 1973 Power Levels of Water-Cooled Nuclear Power Plants Regulatory Guide 3.81973-04-30030 April 1973 Preparation of Environmental Reports for Uranium Mills Regulatory Guide 1.401973-03-16016 March 1973 Qualification Tests of Continuous-Duty Motors Installed Inside the Containment of Water-Cooled Nuclear Power Plants Regulatory Guide 8.51973-02-16016 February 1973 Immediate Evacuation Signal Regulatory Guide 4.11973-01-18018 January 1973 Measuring and Reporting of Radioactivity in the Environs of Nuclear Power Plants Regulatory Guide 1.101973-01-0202 January 1973 Mechanical (Cadweld) Splices in Reinforcing Bars of Category I Concrete Structures Regulatory Guide 1.151972-12-28028 December 1972 Testing of Reinforcing Bars for Category I Concrete Structures Regulatory Guide 5.21972-12-20020 December 1972 Classification of Unirradiated Plutonium and Uranium Scrap Regulatory Guide 1.701972-02-28028 February 1972 Standard Format and Content of Safety Analysis Reports for Nuclear Power Plants ML12298A1181972-02-17017 February 1972 Safety Guide 11, Supplement: Instrument Lines Penetrating Primary Reactor Containment Backfitting Considerations ML13038A4201971-12-29029 December 1971 Safety Guide 19, Nondestructive Examination of Primary Containment Liners ML12216A0181970-12-0101 December 1970 Safety Guide 2, Thermal Shock to Reactor Pressure Vessels 1975-01-31
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September 1973U.S. ATOMIC ENERGY C,,OMMIS$1OiUOREGULATORYARDIRECTORATE OF 911OULATOPIY STANDARDSG lummi D EREGULATORY GUIDE 8.9ACCEPTABLE CONCEPTS, MODELS, EQUATIONS, AND ASSUMPTIONSFOR A BIOASSAY PROGRAMA. INTRODUCTIONSection 20.108, "Orders Requiring Furnishing ofBioassay Services," of 10 CFR Part 20, "Standards forProtection Against Radiation," states that the AtomicEnergy Commission may incorporate provisions in anylicense requiring bioassay measurements as necessary ordesirable to aid in determining the extent of anindividual's exposure to concentrations of radioactivematerial. As used by the Commission, the term bioassayincludes in vivo measurements as well as measurementsof radioactive material in excreta.B. DISCUSSIONAnalytical work involved in the planning and,conduct of a bioassay program includes (1)determination of the conditions under which bioassaysshould be required; (2) selection of measurementtechniques and quality control criteria, measurementfrequency, and program participants; (3) specification ofactions to be taken based on measurement results, withaction points: and (4) interpretation of measurementresults in terms of the location of radioactive material inthe body, the quantity present, the rate of elimination,and the resulting dose or dose commitment. To beacceptable, any analysis of this nature requirestechnically sound concepts, models, equations, andassumptions.The International Commission on RadiologicalProtection (ICRP) has included among its publicationsreports which contain guidance on the protection ofpersonnel from intake of radioactive materials. Severalof these reports make recommendations which can beapplied to bioassay measurements:ICRP Publication 2, Report of ICRP Committee 1Ion Permissible Dose for Internal Radiation (1959)ICRP Publication 6, Recommendations of the ICRP,1962, Supplement to ICRP Publication 2 (1964)JICRP Publication 9, Recommendations of the ICRP11966)ICRP Publication 10, "Evaluation of RadiationDoses to Body Tissues from Internal ContaminationDue to Occupational Exposure," A Report byCommittee 4 (1968)]ICRP Publication 10A, "An Assessment of InternalContamination Resulting from Recurrenit orProlonged Uptakes," A Report by Committee 4('1971)ICRP Publication 12, "General Principles ofMonitoring for Radiation Protection of Workers," AReport by Committee 4 (1969)Commission licensees often make reference to thesepublications when interpreting and reporting bioassaymeasurement results.The concentrations of radioactive material in air andwater that appear in 10 CFR Part 20, Appendix B, arebased on concepts, models, equations, and assumptionsadopted by the ICRP. Therefore a precedent exists forthe acceptability of these as applied to bioassay analysesnece:ssitated by Commission requirements.USAEC REGULATORY GUIDES Copies of published guides may be obtained by request indiciting the divisionsdesired to the U.S. Atomic Energy Commisson. Washington, D.C. 20545.Regulatory Guides are issued to describe and make mvailable to the oublic Attention: Director of Regulatory Standards. Comrrments and suggestions formethods acceptable to the AEC Regulatory staff of Imolemenrting specific pa"ts of improvements in these kuides a-e encouraged and should be sent to the SecretaryConmsession's regulations, to delineate tedhniques used by the st ff in of the Commission, U.. Atomic Energy Commission, Wanhsington, D.C. -luating specific problems or postulated accidents, or to provide guidance 1o Attention. Chief, Public Prooesding Staff.sslicents. Regulatory Guides are not substitute for regulations and compliancewith them is not required. Methods and solutions dIfferent from thos st out in The guitkss are issued in the following ton broad divisions:the guides will be accptable if they provide a bals for the findings requisite tothe issuance or continuance of a permit or license by the Commission. 1. Povwer Reactors 6. Products2. Ressarcit and Tess Reactors 7. Transpoirtaion3. Fuels and Materials Facifitias S. Occupational HealthPublished guids& will be revised periodically. as eopropriate, to accommodato 4. Environmentel endSiting 9. Antitruat Reviewcomrmnts and to reflect new iniormetlon or expsasnco. S. Materials and Plant Protection 10. General C. REGULATORY POSITIONIt is expected that Regulatory Guides to be issuedby the Commission will indicate concepts, models,equations, and assumptions acceptable to the Regulatorystaff for bioassay analyss that are necessitated byCommission requirements. For radionuclides notcovered by a Regulatory Guide on bioassay, the basicinternal dosimetry concepts of the ICRP and the models,equations, and assumptions derived from these conceptsin ICRP Publications 2, 6, 9, 10, 10A, and 12 areacceptable to the Regulatory staff.