ML20149E377
| ML20149E377 | |
| Person / Time | |
|---|---|
| Issue date: | 04/30/1997 |
| From: | Mcguire S, Stewart Schneider NRC OFFICE OF NUCLEAR REGULATORY RESEARCH (RES) |
| To: | |
| References | |
| NUREG-1492, NUREG-1492-ERR, NUDOCS 9707180180 | |
| Download: ML20149E377 (3) | |
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UNITED STATES
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NUCLEAR REGULATORY COMMISSION Washington, D.C. 20555 - 0001 i
April 1997 ERRATA Report Number:
NUREG-1492 Report
Title:
Regulatory Analysis on Criteria for the Release of Patients Administered Radioactive Material Final Report Prepared by:
Office of Nuclear Regulatory Research U.S. Nuclear Regulatory Commission Date Published:
February 1997 Instructions:
Please replace pages A.1 and A.2 in Appendix A with the enclosed pages. In Table A.1, the exposure rate constant (R/ mci-h at 1 cm) for Pd-103 implant has been changed from 1.48 to 0.86.
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l APPENDIX A PARAMETERS AND CALCULATIONS FOR DETERMINING l
RELEASE QUANTITIES AND DOSE RATES FOR RADIONUCLIDES USED IN MEDICINE l
Table A.1 Italf-Lives and Exposure Rate Constants of Radionuclides Used in Medicine * -
Exposure Exposure flatf-Life Rate Constant flatf-Life Rate Constant Radionuclide (days)
(R/ mci-h at I cm)
Radionuclide (days)
(R/ mci-h at i em)
Ag-111 7.45 0.15 Pd-103 implant i6.96 0.86 "
Au-198 2.696 2.3 Re-186 3.777 0.2 Cr-51 27.704 0.16 Re-188 0.708
'O.26 Cu-64 0.529 1.2 Sc-47 3.351 0.56 Cu-67 2.578 0.58 Se-75 119.8 2.6 Ga-67 3.261 0.753 Sm-153 1.946 0.425 1-123 0.55 1.61 Sn-117m 13.61 1.48 l-125 60.14 1.42 Sr-89 50.5 NA' 1-125 implant 60.14 1.11:
Tc-99m 0.251 0.756 I-131 8.04 2.2 TI-201 3.044 0.447 In-111 2.83 3.21 Y-90 2.67 NA' l
tr-192 implant 74.02 4.598 Yb-169 32.01 1.83 P-32 14.29 NA' i
- References for half-lives and exposure rate constants are shown in Table A-2.
" A. Meigooni, S. Sabnis, and R. Nath, " Dosimetry of Palladium-103 Brachytherapy Sources for Permanent implants,*
Endocurietherapy lIyperthermia Oncology, Volume 6, April 1990. The exposure rate constant given is an " apparent" i
value (i.e., with respect to an apparent source activity) and takes into account the attenuation of gamma rays within the implant capsule itself.
8 R. Nath, A.S. Meigooni, and J.A. Meli, " Dosimetry on Transverse Axes of *I and NIr Interstitial Brachytherapy Sources,"
Medical Physics, Volume 17 Number 6 November /Dccember 1990. The exposure rate constant given is a measured value averaged for several source models and takes into account the attenuation of gamma rays within the implant capsule itself.
' Not applicable (NA) because the release activity is not based on beta emissions.
NOTE: Although non-byproduct materials are not regulated by the NRC, information on non-byproduct nuterial is included l
in this regulatory analysis for the convenience of the license.
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A.1 NUREG-1492
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Table A.2 Exposure Rate Constants, Release Activities,and Release Dose Rates '
EO Release Release Activity Based On g
Linear Energy-Exposure Rate 0.5 rem to Total Decas he Rate 8
Intensity Absorption
~
at 1 Aleter llatf-Life" (fraction /
Energy
- Coefficient **
hieV/cm/
R/Ci-br R/ mci-hr Q.
Q.
Q.
for Q.
Isotope (days) disintegration) (AleV)
(1/m) disintegration at I hieter at I cm (mci)
(h1Bq)
(GBq)
(mrem /hr)
Ag-ill 7.45 0.000245 0.022984 4.30E-02 2.42E-09 3.63 E-05 3.63E-04 0.00M62 0.023174 4.00E-02 4.28E-09 6.42E-05 6.42E-04 0.000151 0.0261 2.80E-02 1.10E-09 1.65E-05 1.65E-04 0.001202 0.09675 3.0 % - 03 3.49E-09 5.23E-05 5.23E-04 (Occupancy Factor = 0.25) 0.012291 0.24539 3.60E-03 1.09E-07 1.63E-03 1.63E-02
')
0.0668 0.34213 3.80E-03 8.68E-07 1.30E-02 1.30E-01 0.000559 0.65472 3.80E-03 1.39E-08 2.09E-04 2.09E-03 Exposure Rate Constant (Total)* 1.50E-02 1.50E-01 5.17E +02 1.91E + 04 1.91 E +0i 7.76E + 00 Au-198 2.696 (Occupancy Factor = 0.25)
Exposure Rate Constant" 2.30E -01 2.30E + 00 9.32E +0! 3.45E+03 3.45E +00 2.14E + 01 Cr-51 27.704 (Occt:pancy Factor = 0.25)
Exposure Rate Constant ** 1.60E-02 1.60E-01 1.30E + 02 4.82E+03 4.82E + 00 2.09E + 00 Cu-64 0.529 (Occupancy Factor = 1.0)
Exposure Rate Constant" 1.20E-01 1.20E + 00 2.28E+ 02 8.42E +03 8.42E +00 2.73E + 01 Cu-67 2.578 (Occupancy Factor = 0.25)
Exposure Rate Constant *** 5.80E-02 5.80E-01 3.87E + 02 1.43E + 04 1.43E+01 2.24 E + 01 p
Ga-67 3.261 0.02856 0.091266 3.00E-03 7.82E-08 1.17E-03 1.17E-02 O.357 0.093311 2.95E-03 9.83E-07 1.47E-02 1.47E-01 0.19706 0.18458 3.40E-03 1.24E-06 1.85E-02 1.85E-01 0.02242 0.20895 3.50E-03 1.64E-07 2.46E-03 2.46E-02 (Occupancy Factor = 0.25) 0.15994 0.30022 3.75E-03 1.80E-06 2.70E-02 2.70E-01 0.044768 0.39353 3.90E-03 6.87E-07 1.03E-02 1.03E-01 0.001385 0.88769 3.65E-03 4.49E-08 6.73E-04 6.73E-03 0.001247 0.62941 3.85E-03 3.02E-08 4.53E-04 4.53E-03 Exposure Rate Constant (Tecal)* 7.53E-02 7.53E-01 2.35E +02 8.71E + 03 8.71E +00 1.77E +01
.