ML20149E377

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Errata to Regulatory Analysis on Criteria for Release of Patients Administered Radioactive Matl,Final Rept, Replacing Pages A.1 & A.2 in App a W/Encl Pages.In Table A.1,exposure Rate Constant for Pd-103 Implant Changed
ML20149E377
Person / Time
Issue date: 04/30/1997
From: Mcguire S, Stewart Schneider
NRC OFFICE OF NUCLEAR REGULATORY RESEARCH (RES)
To:
References
NUREG-1492, NUREG-1492-ERR, NUDOCS 9707180180
Download: ML20149E377 (3)


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i E I UNITED STATES  ;

%,*****/ NUCLEAR REGULATORY COMMISSION Washington, D.C. 20555 - 0001 i

April 1997 l

ERRATA l l

l Report Number: NUREG-1492  :

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Report

Title:

Regulatory Analysis on Criteria for the Release of Patients Administered Radioactive Material  ;

Final Report l

Prepared by: Office of Nuclear Regulatory Research U.S. Nuclear Regulatory Commission 1

Date Published: February 1997 Instructions: Please replace pages A.1 and A.2 in Appendix A with the enclosed pages. In Table A.1, the exposure rate constant (R/ mci-h at 1 cm) for Pd-103 implant has been changed from 1.48 to 0.86.

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Publications Branch Office ofInformation Resources Management

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9707180180 970430 PDR NUREG 1492 R PDR l

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l O O l APPENDIX A PARAMETERS AND CALCULATIONS FOR DETERMINING l RELEASE QUANTITIES AND DOSE RATES FOR RADIONUCLIDES USED IN MEDICINE l .

Table A.1 Italf-Lives and Exposure Rate Constants of Radionuclides Used in Medicine * -

Exposure Exposure flatf-Life Rate Constant flatf-Life Rate Constant Radionuclide (days) (R/ mci-h at I cm) Radionuclide (days) (R/ mci-h at i em)

Ag-111 7.45 0.15 Pd-103 implant i6.96 0.86 "

Au-198 2.696 2.3 Re-186 3.777 0.2 Cr-51 27.704 0.16 Re-188 0.708 'O.26 Cu-64 0.529 1.2 Sc-47 3.351 0.56 Cu-67 2.578 0.58 Se-75 119.8 2.6 Ga-67 3.261 0.753 Sm-153 1.946 0.425 1-123 0.55 1.61 Sn-117m 13.61 1.48 l-125 60.14 1.42 Sr-89 50.5 NA' 1-125 implant 60.14 1.11: Tc-99m 0.251 0.756 l l

I-131 8.04 2.2 TI-201 3.044 0.447 l

In-111 2.83 3.21 Y-90 2.67 NA' l

tr-192 implant 74.02 4.598 Yb-169 32.01 1.83 l P-32 14.29 NA' i

  • References for half-lives and exposure rate constants are shown in Table A-2.

" A. Meigooni, S. Sabnis, and R. Nath, " Dosimetry of Palladium-103 Brachytherapy Sources for Permanent implants,*

Endocurietherapy lIyperthermia Oncology, Volume 6, April 1990. The exposure rate constant given is an " apparent" i value (i.e., with respect to an apparent source activity) and takes into account the attenuation of gamma rays within the l implant capsule itself.

8 R. Nath, A.S. Meigooni, and J.A. Meli, " Dosimetry on Transverse Axes of *I and NIr Interstitial Brachytherapy Sources,"

Medical Physics, Volume 17 Number 6 November /Dccember 1990. The exposure rate constant given is a measured value averaged for several source models and takes into account the attenuation of gamma rays within the implant capsule itself.

' Not applicable (NA) because the release activity is not based on beta emissions.

NOTE: Although non-byproduct materials are not regulated by the NRC, information on non-byproduct nuterial is included l in this regulatory analysis for the convenience of the license.

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A.1 NUREG-1492

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] Table A.2 Exposure Rate Constants, Release Activities,and Release Dose Rates '

E O

.'.- Release Activity Based On Release g Linear Energy- Exposure Rate 0.5 rem to Total Decas he Rate

" Absorption Intensity 8 ~

at 1 Aleter llatf-Life" (fraction / Energy

  • Coefficient ** hieV/cm/ R/Ci-br R/ mci-hr Q. Q. Q. for Q.

Isotope (days) disintegration) (AleV) (1/m) disintegration at I hieter at I cm (mci) (h1Bq) (GBq) (mrem /hr)

Ag-ill 7.45 0.000245 0.022984 4.30E-02 2.42E-09 3.63 E-05 3.63E-04 0.00M62 0.023174 4.00E-02 4.28E-09 6.42E-05 6.42E-04 0.000151 0.0261 2.80E-02 1.10E-09 1.65E-05 1.65E-04 0.001202 0.09675 3.0 % - 03 3.49E-09 5.23E-05 5.23E-04 (Occupancy Factor = 0.25) 0.012291 0.0668 0.24539 0.34213 0.000559 0.65472 3.60E-03 3.80E-03 3.80E-03 1.09E-07 8.68E-07 1.39E-08 1.63E-03 1.30E-02 2.09E-04 1.63E-02 1.30E-01 2.09E-03

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Exposure Rate Constant (Total)* 1.50E-02 1.50E-01 5.17E +02 1.91E + 04 1.91 E +0i 7.76E + 00 Au-198 2.696 (Occupancy Factor = 0.25)

> Exposure Rate Constant" 2.30E -01 2.30E + 00 9.32E +0! 3.45E+03 3.45E +00 2.14E + 01 Cr-51 27.704 (Occt:pancy Factor = 0.25)

Exposure Rate Constant ** 1.60E-02 1.60E-01 1.30E + 02 4.82E+03 4.82E + 00 2.09E + 00 Cu-64 0.529 (Occupancy Factor = 1.0)

Exposure Rate Constant" 1.20E-01 1.20E + 00 2.28E+ 02 8.42E +03 8.42E +00 2.73E + 01 Cu-67 2.578 (Occupancy Factor = 0.25)

, Exposure Rate Constant *** 5.80E-02 5.80E-01 3.87E + 02 1.43E + 04 1.43E+01 2.24 E + 01 p 7.82E-08 Ga-67 3.261 0.02856 0.091266 3.00E-03 1.17E-03 1.17E-02 O.357 0.093311 2.95E-03 9.83E-07 1.47E-02 1.47E-01 0.19706 0.18458 3.40E-03 1.24E-06 1.85E-02 1.85E-01 0.02242 0.20895 3.50E-03 1.64E-07 2.46E-03 2.46E-02 (Occupancy Factor = 0.25) 0.15994 0.30022 3.75E-03 1.80E-06 2.70E-02 2.70E-01 0.044768 0.39353 3.90E-03 6.87E-07 1.03E-02 1.03E-01 0.001385 0.88769 3.65E-03 4.49E-08 6.73E-04 6.73E-03 .

0.001247 0.62941 3.85E-03 3.02E-08 4.53E-04 4.53E-03 Exposure Rate Constant (Tecal)* 7.53E-02 7.53E-01 2.35E +02 8.71E + 03 8.71E +00 1.77E +01

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