ML19332C787

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Transcript of Preproposal Conference on RFP RS-OSD-79-010, Study to Determine Feasibility of Conducting Epidemiologic Investigation of Health Effects of Low Level Ionizing Radiation, on 790227 in Silver Spring,Md.Pp 1-29
ML19332C787
Person / Time
Issue date: 02/27/1979
From:
NRC
To:
Shared Package
ML19331A080 List:
References
FOIA-89-446 NUDOCS 8911280546
Download: ML19332C787 (31)


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t e r y r i g h *., T,w i.: nabi ns t.c in i.. Dob l

N4 r bor.t : th. %1o's Yan iv' end from t.he. EPIs,.

p; p Goldr....:: h, ::i t:haci Dr.,,eil'!.ei 4.

14 i

b I's you can tiec, t ho proceedinne are b(-ing 15 roccrded.

We're going to have a t.ranscript mado of the g

y [ en t i: e proc <. li nij n.

I' copy of t his t+anneript. is. going 3 tcL i.

be r"n: oot to <vrrvene that r. coivi d. :.

op*v-of the origin' I

16 i

1 19 [' request for proposal.

jiI-h'e ' 1 1 nir.o hec.o a con.v on f11e in-the: division

'20 for envono V ho vants t.o cc:ne in and - take s ~ lot of contracts

-21 at<it.

2, i

This morning vio hope to civo you. a little more 23 t

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Go d mo rn i;u;, l a.li e r a".1 g rin t 1.:.m a i

' N,l M.v nome iu *: U.o Pnrtont, and this morr a.no. I'll act as hind 10 ] gg. o. noderat e:r t o flesia quer.tiens, nn. I'd li).c to say

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i f t hu r e.; r e. re.e y..cztions rit:. vhi::n ; hr.ve ro:n dif ficul-1 I2 l we will def er giv.nc.

$.o final answers here until the l'

t.n.1 ee get a cons.nnus onetar.

'Then we 'll info.

I3 p a n e l rae. t..n h

yea 01 t.h... ierponsi ias part o f t h e

e. n';.:, c i RPP.

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we'll be all e t o hanctir mo.n t quent. ions completely at this t-I might r.n y that the panol was-primed to respond to a great 16 17 numb..r of wri t t en oua.stionc.

As it t.urnu out, we were I8 un:1:.rwhoined 1.y a t o t a l o f t.wc, and -- bc t h of which I vill il not recrond to.

Mr. Gur.tave will respond to them.

191)..

ll 20 'I to o. ive erme baci.creund as to why we're here, we t.

21 l all know that there 1.as been o great dual of controversy wij l,

22 } respect to the oflccts of e:.:posure to low-level ioni::ing 1

1ccintion.

!mth in the 1 i t e> rei r.n e.ind in the Conurettnional 23 f i

..n Ir r'me <1ui c iviu nr.

As a result o f t-h i !

i. h.arings :hir

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c l f ea r.ibili t */ plar.nirx study to d: termini uh3ther fOllC'# on;

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't; i t i on n ai r e.-

f,anille on.)ow-Jevel Joni; 7

r a d i e. t i o r. < :. f. c t s.

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d The arP that.you have roccived.is the. result of l j

h 5 f in. 73pp,,p;. gj n,.uvr eau areng iTA,1 ;;;c, Ill W, the Veterant..

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i 'lidt. i r. $ s t : a t i on, cind liol) wt t h eteu:.cnt s by other. peopic who y

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A f u.tre interected i n.u.e a ns t h.it worl.

e.:anid be done.

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P lF n o w:rh reepe w..c e.ssentially designed by HEW, b

1, crA, and 1:1;C repren:nt,itiver, and our con + racic people' did-l 10 [' their tailoring to fit.the legalities.

Following l

p I I ! P.r. Gus tavu' r ret. pense to the t'. o writ t en que-t. ions, I willi t

12l the f h.or again and a::h for 'speci fic questions on yoni;'

t r.). O 13' '.part, and we ta'uat we can respond to these adequately.-

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undert who1mi nq a e ' p(it.'.o,t o' t he ur i t ten que n t i enr.,.ind the t.-

16 t wo t.hnt-we have here were submi t ted.by t he ilca) th Systems 1

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l-II I Divi sion of Syst einedies, Incorporated.

4 The first question reads as follows:

"How< rigid-L 4

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1. ; prov id i ni-ij is the than : iin.- tih.lulo f6r pharur 1 l:

20 ll there is no i nt ernal necessi ty :for t.he 60 day limit on-the:

I 21 I!tacksin-phase it-would scom more desirable to allocats t,

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?? i f i u r - no in t hs t re ph. i n e. ene. i nil 1) nnint i.e. i n phane.11 to ennu:.

I 23 vui...i o onci i i t y..:

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q I n..nswer t o t hat oue r.t i on, it is.4mnorativo that

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the schedu.'.e be net.

We have o mandate from Congress that t 1.

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"!'i gh t thch four of l

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phone trut be * :. it ed :8 o f: * *nti t y r"p..a r t e 6n:. di stinct 6

from the phtec :

work th.t :*.u r. t !.c c c::.p t.i t. d wi t hi n 60 7

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ftu. reedily i

.*U availa!.lo in tho litsrnture."

9 Db Th..: r. - v u. : iga i n to that.;ufntion is, no, it's I I ',

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'. l. - ;: or t h.:ve t. l a s, wt '... a.:.; ii * :! no tha t we I2 j con report t o t'e n,: r e r.e. by t.he und of Sente.mbc: of this yea:

12

!;ow, w 're geir.g to be accep*.4 ng gunstions f rort Ii the floor.

i...e r. ;'o u ' r c.: sichnewledged,,r 2 c,'i; e cive your natic 15 and thr3 cc:apany er organi natinn thr.t you r:Tr..nont.

16 4 Mr. Parsont has said, if there are I7 "

any luostions that require any further research on our part.

b IB? we'd l i):e t o 1.a o t he oppor t u n i t y t ri coit.pl e t e thct rencarch n~.1:

(k, and p oviclee you I le-answei n in writt.n f o rra in the alwr.d;wnt 2I'. t im t will !... ' ent out en t he Rl'P:

2I l IMw, I'd like to ash for questions from the 22 floor and lot Mike take over, i

23 b MR. Pl.9SONT:

I'd like to e.s:pand a bit about the

,.1-t i me.n for t.he reports.

NRC and 1:PA are required to respond

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.,, i n......... c 5-to the congrecr by April 1st en their needs and capabilities l

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Ini t i lil y tht'. Cong res,8.$'wr! r(d. the = ontiro study

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j. to J hv ;t.,i:..p l. tc). t y..t. ut....u.a r

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i t u.ir ' riit her obvj ous k

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.d. pt.n e rA i l :. '. t. ~ t h! n.. N.H:l ent ' i e.h un hy..%;itl.*mber.

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study,
  • he e: ',.'. e t e recults of Th'"*. 2,being'the b?. sis 1

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4 f or t he Teptie.S *r 30tn. rr.. p6ntao +o t.';o L Congr ecc.

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- 11 The.g.* for., r.'ne c t.n u^e. thr.t. i t ' c f r:ps rat ive f tha t-o

'12 the l'hsr.o'2

.td b9.m:npl 'ted cc : th:t w can cons.cruct -our p

T report

.r.d ; u t ou r ritptyr.t..ogother f'r t!.p Cnt.gress%.

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g, g. by [f.i p t us)".*r 2 0 rn.

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Mr. Cust ave ntated t hat it is irr. perative that.

the finni. report.be completed within the 1Ekmonth period;of3 16 e

1 it. nuct : be recogni zed Ltha t.-if-thel0:

17 I'

I endor::c t hic t

howcycr, j.

r.ue:cnn f ul blM..: f i n uir. u.:n o su).pative rnaron -- and it

'18 4

11 19 )4 has te be a very good one -- that we will considor an i3 20 i.9 extension.

But for all intente and puri.osor., that 15

') lI-month.;.ir.o period we're tool:ing ut now has been fixed. - I'di i

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.liho to invito questions.

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10l-enn.'.ucta I:.i t eer..t ure.te.a rch.in:) durer ibe thwe. cri,ler*,1 cles w

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n.uEht40 which ate vplicable 10 th5 ntud;. cf } tr.t-level:

N 1,in... ! ng rt.:li n t i on e f f ec t s.

This nhen.3d show nc.o insight 1

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E ihei.n.'ertignt.nrintothe"typer,ofjproblems]

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I3 en the ::ar t et

, r ho r.ight'er.couriter in doiny te.

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15 Tortheriquhtions?

MR. GO!,DSCitMIDTt :The typrs of problems'in b.

- l actual.ly carry ng out t he..lcu-Icvol ion.i zing radiat f ora j

r.

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1,i MM. P/sitsnNT :

Itcrahus some.. insight.-

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kn 1

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Stctvo- !O um, Mt. Sina i.

lIn'9eneral',.

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see:ns that you'io encouracing the investigation of raorc--

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lity'of --

L.one population-or the detenriination of fcasibi n

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.: 3 the f eanj bility of 3 cohine.; nt more than onefpopulation.: C:

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j.cople"1.ivo.

!,o t 's say uvon a t Han:.*: d. - Sculd the peoplo-d (( aiho c.:c' ;.rgntied. th! s : :nt rnet have - the - power tc. go: in and a

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'l nn. Muot:',a With rs8pect to other.Jovernment K r I.f i,

' h apone'.cr.,.I know it..it !;itC can prravid: lini ror. iind mr.ke'

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~ 17 i 3 cok atn.r th+ studiuz thut :have bea:. c'Ono.. H e ' v e' n e c1 c'

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r f arreit.pr.:s at t o st with thrne agtncier right nowp anO.tfr i c<

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y;,.9' provider entry tc' ot. hor governm
ntal agencios.

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1 -can envision wbure thero might be some prob 3c:-

' - wi t.h p; ivat.e corpnvt.tibns 'and - so f or th,

but;wetwillido.

o u r b e:.t te w rii: the winn:ng bidd ?Jan providing-entry.

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a

.g,.l MR. !iLUM t -.But can you-bid en someth ng' if you' d i

y 20I uncertain'about yettint entry?- And $n gener:1 are you O

t'[ encouroWa9 -- it 's scrt-of.iriplicit, even explicit'otipoin-g a

j

,s are vou enceuragino. i he,investic.ation of. ore than one m

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.g J +">pu ).i t i on i n ! 1.e ft wihi1ity study?

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1:ach one could t>e totally Ji f f et ent f.;

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sy t0

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If i t. a;! ^ arc flurine that phM.e tha t the.ro ri ght he so:* e d

le f !:

j.rtP :.> 1., i h. h wr. </hn c'$1t wri:h4.,:

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becaus. * 'ha a* 2I it whcro the iet uni D. t. a *

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t tU MR. H '.;M

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l to I,o.i

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e s:4mi n i ng i

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. e r t.i i n ;. ntir < >. pcpulations to whit che miyht ex pec t., the l'

I I [ h i s.a < $ f i.wi l i ' -

f i a'l '.

,:.0 saigh t c::.en t I!

17l MR.

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MR. f:01,DS CllM1 !.? :

I ht.ve a fi nal question on thn I w.m t t

. :.ih

ti.,d kN th"/ :i2 li '. a: y ; t.pu' it ions ri ght N I'

15 eg,,3g,),od.

g I

16 i

MR..PARSONT:

I sco no reason to consider them a

i 17 ! di f f erently t han any otbr r gepu)a ticnin, recoonizing t. hat. e r.

e b

we uld have t o be' deM i nq wi t h I he mil j t.iry to gr't the data.

18 l>n TiFI;YUR:

N.incy Dreyer, heal th r.ystems divi r i

" Ifli are t.hore any nort of criteria that 70i! Could ye.u comment 21 NRC has set up f or the selection of the bidders to whom thi.

I 22 l would he awardrri to?

For examp.lc, are you interestod 23 specifically in any provit>us demonr.trated experience in 7'. a; radialion?

(

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'H MR. 1%IGO:T:

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N' MR. 1. t.R. Mi i heil:aDJ-.a. J4I.

3.'

a.:

. The" 19' ' o iu r n sr a re:..s o p 'i s e. l Y. where you tN1k' t

s'o ' c.t l e;!. i on f I I c ! of :nt ns At t 5.. + r r w h a e v e r si:e t 3-e i

s

  • i :

ol<ust ihe k.

tv th<i lca sioi J i t y t u f y a.i4 ; ;,r.. G M e pph.a udy; ' h<. w L r.1 ?f d rir-n i

<p, is +ir:~r ari o t ' renpl e not marst li;r 1:

I/r cc:c iw a.aneut 3

n*

theEfn)Jow"oni p,'

a t eJ n !d ' an t.he : u s !!,! ! ii s s'.uW re cp;s t E~

0-st u v.

/.raf i; m! *nt w r k A ry i ni '. v.w r i c :. t initrist.

yet* m f?

+

of t.be f N:ribi lby ruiy.:nd' hnir.:: 2to t very'.Acod prenNet.vut n'

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P AH30H We were :;ut: 0. c o n e r ne d a unu'. tni!..-

c iu <' I J -no t ! c -.h9 t ' J l l;W ! s i e r.phn s i bl t =

p h

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12 Anc as l ', f t i n r. A.

h 13' f or f iir.-11 nu,f." 11 ow -o1 p. i H 1 e r..

9tudie5 rofulting

[

would %

t h i s t' a r 1 t c u l a r e f f o r t.. -' t.h a n the w i no j na hi tfje r :

' {4 14 from

~lS-

' e l i st I n.i t rad f r rm utrtic!phtintiin any ' I n l l o w-on L t.t ud y.1

[j

.lo' Mh.we ve r. it.is notsclaar. and !c might cay it's' c

NHC will not oel directt

'17

'oulte procoble, highly. prob 1blc~that oo b

h 18

'any f ollow-on studie s.

V

' 19 ;

lt's more likely~th9t: iEli - or: sone other governir-n; u

k will hr ve tne "e sponrlbility.

Only in th'e crise wher tr.

6

~

20 o pte n: y.

j g

-m V

21 NRC is re sponsibin for o f olj ow-on 'studV -

r...

Aie you incisiing in this proposa) i 22-MR. !!!.U.Y

~.

H 23 reanalysis of-wcondary data thrit h9vre a2 reedy. been collectri im u, ~

24 MD. PARAD;lT he' r e ont e).c l o fino that' f rom

,! S cons idera t j n'i, hhat we do se l'.h t o - ef f d c our ao r' are studjes th.

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  • r I :' w.

'21 flR..,0b:J t; J -.'ih l : r, t n ~; I tt a a - hr e yeo : r espor dirc L tn s,c

'M

'M Pr!nNT:

There are twoi one on the-House, one 3:

'4' on the ~ SeM'c 4ide.

One is the Hart :iub : D- : 1ttae.-und !=

N 5

nn/t recall in the ho'>rse.

O hc S nll J 4.W ttrM.

thi s..stirh n r s st et ad was:

a The publ l:- ;&w Jn anlch

~

6 Muid thave cny

.7 W e,01.

-1 Tondar 1i Anv nf ' Llie. - ra ne 3

't "mb:' r!

b l

0

- C OtrDM n t 5 b'

9 (IIts r a 5,)Cn 2 0. )

'N. F G:it':.T Shall we'take'a ore 3t ter :offoet.!'

b 3

~ 10 t h e pr e g r e :4 o f t h l :t t. dy w'1 J 15.. a -

',1 1 also lite to r.c-n: tnat liit e r ag. ric y :roup - ind de. wl : L- !*"

'12 watched very clor e! / by tha 13 In close li d i wn md coard!nat ici with 'he !?dt!cnal

(

I nstit ut e s of N ; tn and. othr r UElv 4.:>. enc ies.

14 IS

! rentfont*d at t!.e Outsetthht a: pan *) consi st ird;. '

f 6nd ICr6 ' epr e sent at ' ve s cons.t ro
t ed.t he har 1:-

16-of NRC. S P 8..

Tnte panel was estaoldshed by a memoranium ofl 3i 17 work scope.

.I underst6nding cateen NRC and EPA.-

18-Dr e Y

~

19 The pa ne.1 cons is t s Lof. two r. ember s f rom. HEW 8 :

n.

!! ills, < and I'r. Geort;e Sinon -- pardim, that s LPA -- fer. Charlotte.

j

.20-Silve r nan o f HM. Mr. Fr ank s rs enaul t. ' Mr. r.a r lq Go lle r o f 21 f rom !ll H is he re.

He has. helped by 22 NRC. Dr. 0!ibert Fe-be t

-i 23 comment ing on the RFP and' wi ll be, maybe, a e e nber and l

t 24 observer on' the r eetina of the j nteragency coraittte.

t PS I n]so :n t J c i pa t e that there will be other 1

1 i

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+

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+

-$-.+

=

w l

p 13

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l D4.02'.3' sbH I

r e pr e r,-n t a t i ve s.

shou 21 i1he a short '

[

r orti.e r 1Je s t ! on t.7 P e r h-;' t. we i

2 3

tim *. ten minutef, or so, to allow vau to th!nk stime runr e one! then try, again.

4 about o ther cue:t lon$t (Brjef racers.)

S have your fert!>

MR. 1%i,"3nN T : I....!! e s ind oen t le nen.

o f ut ther wie'.t luns?

i

?

ntndr,..!rv-loped any h

Mr. !!)um?

S MR. i1LU M2 l'm 5ti13 not c-rIsin 1 unclerstand alJ.

9 10 of this.

Phase 1 is really, again, o general statement of in resolvin;:

the i. reb)en area and the approach one would use

.11 12 thir j sue.

!! 'invol ves alret.dy f ield examinstjons and 13 Phase i

reelly ae tting your hands dirty.

14 IS So it s*emr to a.e since e're uncertein as to the 16 accer.snbility of data in Pnase 11. e s p:'c f a l l y if it's not'a really cani 17 government Installation, it seems to me that we will do in Phase what we very specific' statements about 18 nake f rom the proposal.

would resoond to' this request 19 when we 20 In other words, what l ' rr, s a y i nc is it seems that' itself j s e ssentially limited to the elements 21 the pr o po sal in Ph6se 1. J et/ s say Tesk 4 is 22 in Phase 1.

And e ve n You have to go out and see the size 23 already f ield studie s.

variabij j t y in local background 24 of the pop ul e t j o n, the PS radiation. the inobi l i ty r 3t a s.

All that is already bevond I

's* N

,c-jD -.?' 4, 14' w w j 11.'0 6.i .00:1 l~ da.u;Ju* Inn. 1t i s !a t si c:c' i.:i t c n m f fi te f noe : 1 n. 40 -dayr.. k.'.t. v:<, Iq:ch);#r .in n w... ; o;,.;;,.,: 4ne. m j t t o :.3 n3 (- ' lio le s.i t o l t t h v. r v, ve r y o r a a t ; d e t a l l', I woul d ag r ee w i t h ,.3 3- ]- L '4. t h.* t. Ce r t41nl y. th rv are d'.t o a v.tf l oleD1 bout : tuc kgr6 5 .6L . levels the i.rbility of ?cer t ain.ypes o: popuj et i ons j an~.. io ; .f or th Whit.h. c.M oe con: tiler ed wj'.hsut nr.!!n nuti to the"f f e l( J7 B 1 t'.c.O so quite po HJr20

  • hat t r a' t I tho :p orail a t-.

" A 9. whic h mav. a t t'io r e s,ui t, or chown au being feasible <ta c!- c p 1: k 10; .c arry-on Tn3 ; f 1 :- at e.ame li ta r t Me 9:v Ind ic at e some ; gr: R .I l difftcult!er In o,.ttin, tha ac t ua l hta. W '12 - lhJs i s soir:. t h ina th.it we r e c c. ;n i z e. ' y Put.the Pn.e.e I t c rx i s se t tt, :felin ete those s -- R 11 3- _.. - -.( e m po;>u!Atinns wht:h w!)) be stud ch more c loseJ y in Pha se II.

14 -

L. 1 5 Lrecogni; ing that it. in fact, mi;ht not be pots 1FJ+=toEfind) I-16' some of the cata. 'l7 Al so, you'd1 note that in Phasc that. a ' certain p amount of' unde r s t6nding must. hr ora sent on r !.ek - o st imator's 18 19-and so fortn. The se c an be. ac tt.en f e nm. wr.at e ve r pubj~Ic at ions 20 ^ - 21; are avallable. They clo not 1imit-the i n v e s t.19.s t er: t o. ny b v b ?? npec ! f Ic puhl tr.it f orat. We.iM a soma r ecomment!n t lon. butilf P3 the inve sti cator - ha s other re f erences 'thet - he care s to' use,. t 24 .tha t's acc e ptabj c. v 'PS We rio no t e xpe c t the.t-this wi11 be..a simple tssk.L L L N

M5 7%m., n g, y p; - o g-g- ' 3 9, x. atr n - 7: ~u ps-. .m. c c ,4. , % y 7. < .g _ ,m g ')

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  • 'r veJ st!+.ctu as'e ul:H h..: li..ra.JSJnee

-10 Wa dr.,v' t inm. .'h we'rt o H nh.-th'* 9 7. t e>t1: note-wou)dt, 1 m y Lli v.iry;. : a.it 1 y, : f r ; < trii n.Wninhe re' ti.e c rt iacorus right I: c. - , W a1?.

).F r.9

.N it i t..wr e s t i r. a t r,~ r. l t hat.1 P'e ne c 9 s h t' fi e r f om t t.o *P.V.!v,. twc, ma n-ye a t s dr n. -st e rs. I f.;y nit y ! l ? ~ i 13 p '14 -. f os, o cr.i... s t m: th. d;P, e, f 1 o ) d ' d a t a.. w

&. \\

~ 151 19, 00L".20llv1DTi n.stJ uould includC thc1 travel: ,,a x If .ccats? i 171 VR. P/.lGONT4 No t tie c e ssar t i v. That wouldfbe uph ifV =L ' I fi th'e ot r! derf t o hlw Mn e st inate. y p m 14 Mr!.t ual,1;Wil'4] DT L.'.'o,. t n e' 7.s c,1; 4 i n ;i'n n.e.e ! ). t A r ti y t.s t ti J ) t ! :.u r, e ' t h ^ tis ;nte t -K t 0 - me.'ll ch ! 4 .?N p i t,i!; li n X:ine:t_. * '21~ 8 ur v e 1 ! j.ust: ;racedures?- iM r e x wui e, ,s s-unde r t ne OSilA-iy. g 772 M t: r g:er:ilth; ) w dose rndistlon?- .,u 23' f.9. F/ ;.h).'iT : ' W e ' r e J e a v !n-) this open to.the' " ~ ( ' nveutivttor to r"copraend whate ver he f eels js appropriate m. - <N i M ,l2 e a nd tser o sv.b r y. n t ~- k.', 3 s. { b 4 6. ,'.'j 5 p< ^..y J1 g -m f

g$q q ; ' f 9 4 ge m = <m y:g '. : ,u, T 116? }$,p[.h,gy; c. r q l-p.y. Jn! n g! w;D rs. sq,! Tast " '. 1 A not us! t < 'e) ea6 .y <r . a.i '.+. ; di v e n' t h a t t.<'.> p : i 'irL t o - % v e n V4 Jl, ,,, y.. g .h- 'Miv > ' el o ' re [." h i sorat to control. popul e tions ' f rc, :.c t udy p.>pul at !:n t.

1 p

. l.n ' othe r words. what..woul d - be : 6:co p!ish?d ; in{you 4 T

m. '

~l-4p !.i : Vt.,4, ey ,6 5)( 5 7. i;& .. t h' re. are 'c e rt o!ri F R, 'sA RLO,*i r i, J.'ie - r r a l 1 : e - t ha t F~ .o y _; > pn;ut!at ion, f cr. Ahl:h i the ret may - not be.'a r.orepr i h* e f j e;c:- )' ;- 0.

  • d a i., and'w< Luculd 1ike 1the :binfer to est Mate whet ~1t would 3,

3;f% V . t ot. e.. o. raale.l-tho se, or.- to c ons t ruc t ' the data. or< : r e cons tr uc t MQ ~ 10. .the Yata'.orJinfsome;mannertprovide the dato for those q I.l l ? 'groupe,. . N euj at (cas 12 'MR. M!. N ::!iv.1 DT 3 - Art 1.hese (. o ni. r o l N r e l a t e d. to r.t o.iy' pripolii t tons pr e v ious l y fi!cnt I f l ed ?. i5 , x, +I 14' MR. PARCONT4 They may be, t' ,. y. IS' - Fo r ' (! xamol a..for (- st udy popu! at f or' which :1sj f ai rI 31 6 Ne 121 d:f inerf 7ntwh!ch may present di f f j cul t les. on the- .n cont rol 'sice,- and 'Jn that part icular si t uation. It 'one f eels ,m l"l ' 18L that t.hi s ! s ir.n e r: e l l e n t s t udyE popul at ion, but for the-n. N'.< --) o ' Jact ofn adecuate contro l populat ion, that-it becomes.-lessi . c., ~ L t.h'in W d '!Le t o .c ae f.or. 4

;> df f ne jbl el t o carry not l'h+ P t u:f y.

- ? l- ..o r :t ; o r - w r l I t.* o.l o.t's ni t l on nr- -'.ome '.in i of an'aipratich 4 J2 .to hu!Id or to taljor toe cont.: ol popu l,it t on.. 1 P3 MR. GO!.1)SCiiM! DT That's the intent =of Task ~5. 1 B ? 24 MR. PARSONT:- Yes. 25 MR. G01.Dsclivl DT: One last questjon. 1t re1at'es tc4 a (- i l J g i j I i i k i t f _-( % ; - 3. U! w., 'i

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p MR. l Rt'n '::sTE;::: This is:n-nt a wish; thanLa7 l 1, 10 l' W areful'V.hvecht-vet process that we her"e in -indLhere. 4 41 0 1 the bidder displayclinc;onuityfitsinn 0 h'c aitent t h e. t 12 [ to ' ~ 'in-hisit avor. towar'd _getting the eontract. i"

M 33

~ !:R. par.SO:,T :: ' e'11 define it clos:ely. l ..l' [ y s i ~;sre you talkinci;nbout sensitiv-; MR. G01.or:C11MID": m ij : i I tSo :ri sh invo'ved, or are-- you ' asking ' for: rer; .. ann 3yrin as;to: 16 monda t.j unu sf e>:pono re :levci s?- 4 j7 MR. PARSO:T; Let's withhold that.. q gg-Is there = another questic,n here? sjp l DR. IlODTOS: Hooton, University of Pennsylvania;! i I . pp t l~ On-the conflict of interest question,.how deep 1; 73 i pp [ that necussarily go? Does it apply only to tho ' prirne con-', a 73 t.ractor? Does it apply to t.he subcc.ntractor? Does it 6ppy< .to eminu): ants who may have been consulted by > the priano cor' s i p.s I; !~ t' 4 25 i tractor? 1 f /, rl ' "'J: r.

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un.s t.- uort at 13 effort and hc .uch c:aphasi s <!c you havn in mind for that 14 portion of tl.c study? 15 MW. i' Ai~ Sn:!T: We f e el that s.-v conr. icie ra t i on sht.* ot;.or de l e tte rious heal tn e t, act s such as potent.h : .16 he ende of 17 oen et ic e f f <:c t s, consid:ra t ic.n; of. If'one will, unspectfIc-19 Jjfe span shortenina. 10 There are a whole !!st of potential health ef f ec t. 2 C-We rio e xpec t, no u e v :$ r. that th. c.ain c'oncesis :hould be on 21 tho.*e health affects whicn ara recogn!.ed as beinc ma,}or R pi;entini lie.n I t h e f f a r. t - f i n'r.. s pri.or o tn low Iri v e J-l o n ! 7 i n. 23 redintion. 24 DR. STRAi!GE: Strange, Franklin institute. 25 I think you raised a quest 100 when you answered t'

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3 You're not eyeluding unborn? e 4-l!.3. P ARSONT: !!o, we're not ex c.l udi ng '.ncorn. ' f RA!". E 4 1 was try na to f'ytre cut if you were, 5 Dl!. J if Tosh 3 was where we were being concer*ie:- y 6, tal): f r:9 re sout 7 with-these ! @ss, n-whether nr not uhi' vau,lu:t said t me in c a ru r. i s a s t o i v conducted on 8 impl i e d ' "a. t th O 9' populations. 10 r!.9. P A RCO NT : 1 thini: Task 2 i s presented so that- i. e f ull view rather than concentrating in _one ,11 We ecn get 12 s pec t;'ic brr e. 13 We recognize that the controversy is not sp eci f i c \\ over other effects as wcJ1. 14 over carcinogenesis, but 15 MR. P ARS')NT8 1f t'here a re no-othe r q ue s t ions -- b lo DR. Il00TnN I have,l u s t one nnall point. 17 Would it be possible-to have the transcripts and 18 any revls!ons sent to people.who are here even if they're '19 not on the origiraal list of RFP recipients? !?O AR. GUSTAvp .r>h, yes. You will have to reglst*r, 21 though. 22 DR. it00 TUN: I did. register, but I dfdn't get the 23 RFP original) y. 24 MR. GUST,WE s Then.we don't have your address, so 25 You're galna to have to rentster with your complete mailing l

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_f 29 - ew Page 19 o + p OTHER CC'mCMTIONS LB. 1. Cost Evaluation . A separate cost cnalysis will be performed on each business proposal. To piovide c co ron base.for evaluatien of business proposals, level of.cifort data shall be et. pressed as nan-hours. Award teill be made to the offeror presenting-the best overall proposal .with consi& rction being given to Orgeni:ational Cepubilities, Technical Approach, and Estimated Coste. The relative importance of Organizational. Captoilitier and Technical Approach is shown by the nur..erical weights Estimated Custs is less important then the other two assigned to eatn. hearJ vill not r.ccessarily be made to the. offeror uith the lowest areas. es tir:ete'J costs. Estimatori Costs will ba ceterninhtive only when there.is no substantial difierence in the aggrcoate quality of the Organizational Capabilities and Technical Approach between offerors being considered for award. The povernment reserves the right to nahe an award to the best advantage l of the gcvarnt,'ei.t, cost and other factors considered. 2. Conflict of interest There are two paramount principics which the Commission must consider -i i in determining if a conflict of interest would cxist by award of this worL ' (a) liight the cward in any way give rise to a conflict that biases or prejudicos the results that the Com.ission expects?. (b) Might the award put the contractor in an unfair competitive. advantage with respect to other contractors? In order to assistithe Con';nission in applying the above two principles to submitted proposals, the offeror should describe any significant contractuai and organizaticnal relationships of the offeror, its I employees or exoected subcciitractors on this contract, with industry associations-(e.g., utilities, etc. ) and suppliers thereof (e.g., archi-1 tect engineers and reactor manufacturers, etc.) which might give rise to an apparent or actual conflict of interest in the event of a contract cuard to an offeror. Excmples of some of.the relationships which would be of concern to the liRC in this context are generally described in the NRC General Staten;cnt of policy Regarding the Avoidance of Contractor Organizational Conflicts of Interest, copy of which is attached for your ] information. The possibility that an offeror which roccives this contract could l j benefit from the conclusion that further epidemiologic research is 1 i feasible by way of participating in such a follow-on effort gives rise j to an inherent conflict of interest. It is therefore anticipated that the contract u111 contain language excluding the successful offeror from participating in follew-on effort in the event that such 'ollow-on effort is undertaken by the NRC. n,,.,, e.,,,,

y m .y -RFP RS-0SD-79-010 Pg _. > -Page 20 of.29- .f E. C..T,_103_.E. - ~PART 111 CONTr.ACT SCHEPULE ,g :, e SCOPE OF WDEP., TERPS ant' CONDIT10NS ARTICLE 1 .57*7E"ENT or 'iORK i 5 A. HI STMY_ 0tian Act of 1974, es m.anded, alolished the A:omic Enercy Ccriissien ( A C) e :d cr>;eted a n(W cacncy, the 'huclur Re The EnerEy F.;tergani: Co:nission!(NRC), to which was trcnsferred the licer.;ing and related I F reculctory authority of the AEC under the Atcmic Energy Act of 199 h NRC he Energ'.c Reorganizatic.n Act also added :vthority for t eEntr';y R ~ ' c. mend ed. lto licens! and rc9ulate certcin facilities of Li:e0 t ion (ERD.*.), whic Developmen.= Administ: A.Stucv to Datermine the feasibilitv of Conductino an-EDIrITIoWiiF1 n"e s t : e a t wri Ti tue isa'TtTfGic PROJECT-TITLE: ~~~ [L[oELTv'eI~1onTTiiio i;aojM~ .,J BACKCROUND AND 03JECTWLS 8. To improve t he scientific bcsis f or their rec .e lferc. in consultation with the Departnent of Ilealth. Education anj '.;e idemiolon:c will ' support a. study to assess the feasibility of performino ep i l investications of the health effects incoced by exposure to low The purrese of 'his feasibility study is te h ascertain the overall'value and likelibcod of scient of ionirino radidtion. 1 epidemiolooic investications. l The dose levels of Primary interest are those applicable to co t l en-experienced by populations both in the work plac viror.mont. q It can be assumed that t he l uman health effe h. '." ] of radictien exposure are similar to those observed non:, ally in r,ased on the Present body oi knowledce, t he prc mein g detectable health ef f ect is the in:hiction of neoplastic diseases.for populations, r - ever, there are other human health ef fects in'n Such et f ectt. ere also of intere.;t i estimates are availchle. Publications of the Cc :mittee on the Bioleo (: Jenizine Radiation (PEIR) c' t he Natinnal /.cademy of Science 5. study. f I.: cM *- the United Mction's Scient i fic Com":it tee on the Ef icct s o I Radiation (UHSCEM) and other relevant rublicaticos shoulf in makinn assumptions on dose-ef fect relationships and co references for these ef fects. risk estimates. ' i L?

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  • i RFP1RS-0SD99-010 1

g ~ P6ge/21:of 29 + g? he .m a .m /p = The cycrall ch.ie: Lives of this f easibilitySstudy cre:. p R' (4i). to-define the statistical. technical. and adminit.trative st#noths h! and constroints rhich are ir.herent in the conduct of epider.1nlo':ic ' studict on sub.iects. exposed to low-ievol ioni:ir p.rediatnri;- I"' (ii)1 to' ennine the merit of conducting such epider;iolccic !!t; dies on : ~, the herh h ef fccts of Icw-level icnizino radiaticn evposure in p, 11ight of the strengths and. constraints-identitied it, (i) above'.. current'I.nowledce of biological ef fects and the cherccteristics off g B candidite populetions.i 4 k. i C. - STATEMEllT OF llOpH-P o The Contractor.shall-' provide the necessary persennel, f acilities. naterials, ano wrvicesLto acccanlisikthe specific ' tasks listed helea. '?he effert h _ hereunder will be sccomplished in tv(o phases the details-of which arei J presented in the secpe of work which follows, t I.^ k Phasc 1. rrtEL1MitlAi(Y At:ALYS1S Of STATISTICAL STRE::GTHS A m L!!'lTAllo::SL b, Task 1). Conduct a literature. search and identify various rethods of ~ conductiho epidemiolonic investioations relevant to -the ef fects r of low-level ionizinc radiction. 'l 1: Task.2). Provide a ispecific evaluation of t he strenoths and linitations of ~ epidemiclooic nietheds Lto estinate t he' risk of health ef fects-frcn exposure to low-level ionizine radiation in various'popu-' q,'. lations receivino radiat ion' doses in excess of " normal".bacimrannu ~ l evel s.. The contractor may propose. erd evaluate any suitable o epidemiologic ntethods notuidentified by the literature. search.

Th'e evaluction thall adcress t he influencfof data anality.

~ potenti al conf oundi.r.g or ef'ect-modi f yi nc environmental. deme- - j oraphic.and other' pertinent -f actors; the possible accuisition e' . adequate pooulation. size for study; and t he capacity to discrirdra:el- - between incremental' radiation induced i:ist and existing "norna'" y risk of health eif ects. + Tasl:- 3) Based on currently available risl: estimates and dose-effect relationshirs,. assess the ' likelihood of epidemiolooic studies distinnuishino increnental radiation induced health ef fects-7 f ren conditions end diserders nornally eccurrirp. The nosi reports cf t he i:E!H Cm;ittec. (8:.SCFAR and other relevant recent publications shcIl be used es cuides for both of these f actors. The rance of rish estir:ates shall l'e included in the analyses. based on t.hichever publications are sclet ted. 4 The populations identified f or this pursese shall include, but do not have to be linited to: cccupat icnally exposed individuals; resident s in arcat with high nctural ind/er technologically enhalv.ed backcrenrd; rM idelit s i n c r e.15 cf nuclear facilities; m

f/P RS 0$0-79-010-- t Page 22 of-29 4 e, L N h and groups exoosed during ::cdical procedures other than for the i L treatment of neoplastic diseases, foralations wnico have been the subject of previo:ss.epidemiologic investigations of the ef fects of s low-level ionizing radiation shall also be included, i Task 4) Deterr.iine which of the populations. identified in Task 3 above are s most. suitable for epidemiologic studies of tne re31tn ef fects of-low-level ioni:ing radiation. Determination shall to t'ased on such factors as study and control population cc.mosition and size; potential confou.1 ding facters; variability in lec3F background radiation; variability in local' rates of-bealth ef fa:ts; and popu-l lation roobility. EAplain why other popyldtions ida tified in Task '3 above are not considered suitable for furner study, and. examine at wnat level of risk and/or e>posure epidaniologic studies on such populations tecome feasible. Note: Phase I must be corp!cted and.a report sulcitted to the fiRC within. sixty (60) days after the effectivo date of the contract. Phase II. DETAILED SCIENTITIC CONSIDERATIONS Of FEASIGil.lTY AND COST BASED ON FIELD EXAhlNATION Of RELEVANT POPULATION ' l-CHARACTERISTICS. Ta sk - 1 )' for each of.'.he populations identified in Dhase 1, Task 4, as suitable for epidmaiologic studies on health effects of low-level ionizing radiation, de ormine the nature,- form, extent, cuality and recessibility of existing health and radiation exposure data. Radiation exposure' data should take into account the various characteristics of the dif.ferent types of ionizing radiations. I The Contractor shall identi fy and estirr. ate the nagnitude of the uncertainties in the radiation exposure data. -Investigate and discuss potential control populations and evaluate their potential contributions to an epidemiologic study cr studies and provide cost estinates for such studies. I der.t i f) and assess potential confounding and ef fect-modifying factors relative to the study and control populations under considerction. Recon rend' those specific sources of = data most appropriate to such a study. Task 2)a Assess, based on Task 1, if it is possible to accomplish with existing data (for specific cancer sites, types and total cancer) either or both of the following objectives: ( i) Describe and quantify, usino medels and statistical analyses, including confidence intervels, the excess of cancer arising f rom exposure to low-level ionizing radiation. Include 3 discussion of considerations of i-L study and control population size with dif ferent anticipated / levels of risk and exposures and how confidence limits are af fected by variations in these parameters, i (ii) Describe an upper bound of risk for radiation-induced emn

s ~ eIgl: V" RFP RS-0SD-79-010 Page' 23 of 29 r -7 A lt:it not iiilende"' that the contractor will develop specific models. However. :no_ contr cctor can select apriropriate nodels for illustrative purposes. 2)b:l Tor each population and epidemiologic approach considered, analyze the interrelationships among scope. duration and and cost. Explore which, if any, other deleterious health ef fects resulting Task 3) from exposure to low-level ionizino radiation can be successfully j studied in epidemiologic investigations of the selected populations. I Identify hcw current d6tc bases end record keepinq practices could Task 4) This i be improved for continuing epideniolegic studio:; in this area. shall include identification of possible new data bases and record keeping practices.that should he initiated to support epidemiologic_ -

  • studies in the future.

Task 5).for potential control populations that were eliminated from further considerttion because of-the lack of recdily available health or exposure data, identify thoso, if any, for which sono useful estimato could be obtained by field recenstructuion ni the neces ary For such populations, estimate the effort that would be data. involved in collecting (or recnnstructing) the necess :ry data and-the quality of the expected epidemiologic results. - U.'- REPORT REfqU!REMElii3 The technical reports listed below are to be documented, produced and disseminated in accordance with f1RC Mcnual Chapter 3202, which is part of this contract. Y ". g'

g RfP P,5-CSU-i. Pace P.i of 29 1. SPECIFIC REP 0nl - MOUMi NglS l Monthly letter progress report, in one (1) copy to the Contracting - a. Officer's Autnorized Ret resentative (COAL) and one (1) copy to i the Contracting Officer, shall hn due by :ne 10th day of each month and shall include as a c.inimwn: i. A technical. report of progress describing findings to.date, prot 1 cms incurred and solutions proposed, cod plans for the 'erisuil89 Month. ii. A.eport of costs incurred f.c date as follows: Direct Labor Costs Ti; vel Expenses Overhood Adriitional Costs . forecasts for-Contract Cemeietion b. Within sixty (CO) days af ter the effective date of the contract, the centractor thall submit a comprehensive report on the final results of Pha ( A comprehensive sur.;rary report on the results of Phase 1 and rciti; c. to date oLiained on phase 11 shal.1 be. submitted on_ August 31, lib. d. A progress report on Ph:sse 11 shall be submitted two (2) weeks prior to the eighth (Uth) month meeting. e. The final report shall be submitted in one (ll reproducible'icaMr'- ready) copy and five (5) copics to the C0AR and one (1) copy te.th. Contracting 0f ficer. E. SCHEDULE Phase ! - Complete within sixty (60) days after award of contract Final Report ~ - Complete within fifteen (15) uonths after award 'of contract F. 11EETillGS The contractor shall participate in various neetings with the imC staf f during the contract period. The schedule of thest mcetings follows: (1) Approximately two weeks af ter the ef fective l ate of the contract. members of the.2C staff shall taeet with tne contractor's rerrese a tives at tie contractor's fccility (place of perfornance) to disc. the progress (.nd direction of Posse 1. (2) On September 10,1979 (at a time to be assioned at a later I date), the contractor shall Ret with members of the llRC staf at the NRC of fices, tiicholson Lar.e, Rockville, Maryland, and N prepared t.] discuss the August 31, 1979 report.

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j m,. %]..l{" h 14, -i M@l DEPARTMENT CF HEALTH.' EDUCATION. AND WELTARE f b PueLic HCALTH stRvect :- I etNTan Fon c:St ASE coNTaoL- .s NATIONAL ONSTITUTC FOR OCCUPATIONAL S AFETV ANg Mg AL9g , R0staf A, T AFT L ABOR ATOnttS - 4874 COLUMBI A PAMMWAY. CONCINN Ati, OMIO 88888 4 June 27,.1979 { i; Dr. Elliott Stonehill Program Analysis and Formulation Branch National Cencer Institute, NIH Building 31, Room 10 A 52 .Bethesda, Maryland 20205' -Dear Dr. Stonehill - At'the request of Dr.' Anthony Robbins I am sending you the material. 'a . I received June 5,1979 from NRC staff members, Mr.; Robert Purple After c review by and reaction from NIOSH and Mr. Mike Parsont.- , staff it is our plan to meet with Mr. Purple and his staff ' for the 5: purpose of discussing the-data needed for establishing a registry of }- TMI workers. a g' ' Sincerely yours, ) [ Todd M. Frazier )-, { Chief, Surveillance Branch-j l= Division'of' Surveillance, Hazard l. Evaluations, and Field Studies - ;i Enclosure I $1 f t t .l S l r; =m -+,-w -y e ,,v+ --}}