ML20125C295
| ML20125C295 | |
| Person / Time | |
|---|---|
| Issue date: | 08/15/1979 |
| From: | Harold Denton Office of Nuclear Reactor Regulation |
| To: | Ahearne J NRC COMMISSION (OCM) |
| Shared Package | |
| ML20125C287 | List: |
| References | |
| NUDOCS 8001080321 | |
| Download: ML20125C295 (3) | |
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MEMORAMDUM FOR:
Commissionerhhearne
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1 Harold R. Denton, Director', Office of Huclear Reactor
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SUSJECT:
USE OF THYROID BLOCKING AGEMTS.,.
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...:Q, In response to your July 30, 1979 memorandum on the above subject, a reeting was held on August 3,1979 in which tembers of the MRC staf f.who have been
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attendance list is enclosed..
e a In answer to your fu'rther coh.ents and question, and in summary of the teating.
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Our July 13, 1979 temorandun comment regarding a meeting with FD.i "to expedite consideration of the matter" can be further explained as follcws.
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"'n i The GSA Federal Register flotice of December 24,1975 (40 FR 59'N) on Radioic;ical Incident Emergency Response Planning:
Fixed Facilities aml A 9 Transi ortation, states the responsibilities as agreed between certain i
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. Federal Acencies. 'In delineating responsibilities, the GSA notice nahes G
the MRC the lead agency in radiological incident emergency r'es:cnse plan-l VFs'.
ning, training and other assis'tance covered in the notice. - EFA has,
-9 among other responsibilities, the establishment of Protective Action 5
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Guides, and recommendations as to appropriate protective actions which 1can be taken by government authorities to aceliorate the consequences
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of a radiological incideryt.
HEU has respons'ibility for essisting Stata O
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health departments, State hospital associations, etc., in the develop ent of plans for the prevention of adverse effects from exposu're to radiation..
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including the use of prophylactic drugs to reduce radiation dose to scec-
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This includes health and medical care responses to radio-J +%
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~.1.~. logical incidents, consistent with guidelines issued by URC. -
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~ A 'tecting'of NRC sta'ff with the Bureau of Radiolo'gical Health of FDA is scheduled for August 21, 1979. This meeting will. discuss their plans for; L.], M -
providing further appropriate (medical) guidance, in view of the FDA pr j%
posed guidance (43 FR 58793) of Decenber 15,1976 (still not finalized)
W establishing actions to be taken in the event of a contaminating raditicy
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J ical incident, and the request (43 FR 58793) for subnissions f u drug
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..,.M applications for potassium iodide in oral dosage forms for use as a thyroid blocking agent. This latter request concluded that potassium' iodide is safe and effective for use as a thyroid-blocking agent in a
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-radiation emergency.
FDA approval of one company's drug application is. within a couple of weeks of being issued. As mentioned in our ear. lier
. response, URC R.G.1.101 already mentions' that use of radioprotective
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The majority of the staff present at the July 30 mee' ting agree that the '
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Aj use of potassium iodide as a thyroid blocking agent in the event of riate part possible inhalation or ingestion of radiciodine is an apprcp'ogram would T. '3 of a complete emergency preparedness ' program. A complete pr 1,~2@
. include countermeasures such as source interdiction,'. shMtering, evacua-
-W tion, respiratory protection, protective clothing, importing of foodstuffs d
and water, decentamination, chemical treatmant and o'thers. The major reason that some staff members disagree on use of KI-is that they believe that other measures in the above list are more inportant.for most radio-logical incidents and that a widespread stockpiling requirafaent for KI c, a would not be cost effective.
It is our intention, however, to press for
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FDA action in their role as the agency to supply medical guidance, as
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discussed above.
This will be a subject for the August 21 meeting.
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The action plan for promptly inproving (licensee) emergency preparedness j
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has been forwarded as SECY 79-450 of July 23, 1979, an information report.
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Unile that report does not specifically address the use of l'I, upgrading of licensee plan's to meet the guidance of R.G.1.101 will include the 1-review of their plan to use radioprotective drugs.
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+ Harold R. Denton, Director '
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Enclosure:
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Chairman Hendrie
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- Commissioner Gilinsky
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. Commissioner Bradford 1l" SECY OPE
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!!EETI?!G RE USE CF KI AS Ti.YROID BLOCKIt!G /6E!;T
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