ML20198N513
| ML20198N513 | |
| Person / Time | |
|---|---|
| Site: | University of Missouri-Columbia |
| Issue date: | 01/12/1998 |
| From: | Charlson E MISSOURI, UNIV. OF, COLUMBIA, MO |
| To: | NRC (Affiliation Not Assigned), NRC OFFICE OF INFORMATION RESOURCES MANAGEMENT (IRM) |
| References | |
| NUDOCS 9801210101 | |
| Download: ML20198N513 (32) | |
Text
{{#Wiki_filter:_ _ _ _ _ _ _ _ _ _ _ _ 'Il Of'fice of the Provost "4> = Ha" Columbia, Mo 65211 ^
.. (' yL University ofMissouri-Columbia '
rnoxr (573) 882-6596
,. rAx (573) 882-0080 January 12,1998 3
Director of Nuclear Reactor Regulation US Nuclear Regulatory Commission ATfN:- Document Control Desk
' Mail Station PI-37 Washington, DC 20555
REFERENCE:
Docket 50-186 University of Missouri Research Reactor License R-103
SUBJECT:
Research Center Director-The University of Missouri-Columbia (MU) appointed Dr. Edward A. Deutsch as the Director of the MU Research Reactor (MURR) effective December 1,1997. As shown in the enclosed curriculum vitae, he brings to the position a strong background in business management and academic resetrch. in both arenas he has demonstrated the ability to make significant advancements in radiopharmaceutical research and development while complying with and meeting federal regulations. We are confident that he can provide the dicection to the strong MURR team to make further contributions which are in keeping with the Atomic Energy Act goals for research reactors. Dr. Deutsch's management team includes Mr. J. Charles McKibben, Associate Director for Rescaith Opecations, to whom he has delegated the responsibility for reactor operations and licensed activities. Sincerely, Q&1LL WI Elaine Charlson Associate Provost djs Attachment i e Reactor. Advisory Committee RAC Safety Subcommittee Mr. Tom Burdick, US NRC Region III
- Mr. Al Adams, US NRC, Washington, DC
- k. .h f
j Acting Provost Brady J. Deaten
~
9801210101 980112 PDR P ADOCK 05000186 PDR AN (QUAL OPPtwrtwin/ADA NTrrt rum
Revised 12/5/97
, EDWARD A. DEUTSCH CURRICULUM VITA
' PERSONAL DA TA -
Binhdate: July 13,194' Birthplace: - New York, New York EDUCA TION B.S. (Chemistry) University of Rochester,1963 Ph.D.(Inorganic Chemistry) Stanford University,1967 ACADEMICEXPERIENCE USPHS Postdoctoral Fellow University of California at San Diego,1967-68 Instructor of Chemistry University of Chicago,1968-70 Assistant Professor of Chemistry University of Chicago,1970-73 Associate Professor of Chemistry University of Cincinnati,1973-78 Professor of Chemistry University of Cincinnati,1978-91 Professor of Radiology University of Cincinnati,1980-91 Volunteer Professor of Radiology University of Cincinnati,1991-present
- Adjunct Professor of Radiology . Washington University,1992 9 resent
. Director, Research Reactor Center University of Missouri-Columbia,1997-present Research Professor of Chemistry University of Missouri-Columbia,1997-present Research Professor of Radiology University of Missouri-Columbia,1997-present l
INDUSTRIAL EXPERISVCE [Mallinckrodt Medical, Inc.] Director, Nuclear Medi ane R&D 1989-91 Vice President, Imaging R&D 1991-97 CURRENTRESEARCHINTERESTS Chemistry of technetium and then m for use in nuclear medicine; multi-modality imaging of oncological and cardiovascular diseases; new medical imaging technimes, especially near infrared imaging; therapeutic nuclear medicine; chemistry of Group III metals for use m medical diagnosis and therapy; bioinorganic chemistry. ACTIVITIES Visiting Scientist, Argonne National Laboratories,1969 91 Visiting Scientist, Brookhaven National Laboratory,1980-95 Visiting Scientist, Consiglio Nazionale delle Richerche. Italy,1986-89 Member, Board of Directors, Radiopharmaceutical Science Council of the Society of Nuclear Medicine,1981-83 Vice-Chairman, Chemistry Abstracts,1983 Society of Nuclear Medicine Scientific Program Committee, 1982-83 Vice-Chairman, Chemistry Abstracts,1986 Society of Nuclear Medicine Scientific Program Committee, 1985-86. - Director, Biomedical Chemistry Research Center, University of Cincinnati,1986-91 Member, Editorial Board, INORGANIC CHEMISTRY,1986-89 1 President-Elect, Radiopharmaceutical Science Council of the Society of Nuclear Medicine, 1987-88 President, Radio' pharmaceutical Science Council of the Society of Nuclear Medicine, 1988-89 Member, Organizing Committee for High Country Nuclear Medicine Conference,1989-93 Member, Medical and Scientific Committee, Eastem Missouri Chapter, Arthritis Foundation, 1992-94
- SOCIETIES Society of Nuclear Medicine American Association for the Advancement of Science American Society of Nuclear Cardiology
d 'A!Deutsch -
- H NORS
' 11980 - Cincinnati Chemist of the Year Award, A.C.S., Cincinnati Section _
1981 - Distinguished Scientist, Technical and Scientific Societies of Cincinnsd - 1985 - Fellow of the Graduate School, University of Cincinnei - 1991 -;St. Louis Star Scientist, St. Louis Science Center : 1994 - Gold Medal and Diploma, Science Award of the University of Padua, Padua, Italy . PROFESSIONAL TRAINING COURSES COMPLETED
. Penn State Executive Program
" Engineer / Scientist as Manager" October 27 -November 8,1991 University Park, Pennsylvania Center for Creative I *adership
" Leadership Development Program" i July 25-30,1993-
- Colorado Springs, Colorado Industrial Research Institute Tutorial on " Third Generation R&D" led by A.D. Little, Inc.
April 29 - May 1,1994 Palm Desert, California , The Wharton School-University of Pennsylvania
" Finance and Accounting for the Non-Financial Manager" May 18-23,1997 Philadelphia, Pennsylvania PASTGRANTSAND CONTRACTS .
Noncoordinating Buffers, sponsored by Research Comoration,1965-67, $16,000 Chemistry of Platinum Anti-tumor Agents, sponsored by American Cancer Society, 1969-71, $12,000 Noncoordinating Buffers, sponsored by National Science Foundation,1969-71, $15,000 Kinetic Studies on Transuranium Elements, sponsored by Argonne National Laboratory Faculty Research Program, 1974, $2,100 -
. Kinetic Studies in Modern Inorganic Chemistry, sponsored by the University of Cincinnati Research Council,1974, $4,000 Summer Faculty Research Fellowship, sponsored by the University of Cincinnati Research Council, 1975, $2,600 Development of Technetium Chemistry for Use in Nuclear Medicine, sponsored by the Biomedical Research Fellowship through the University Research Council,1976, $3,290; renewed for 1977, $2,900 Development ofTechnetium Chemistry for Use in Nuclear Medicine, sponsored by the University of Cinemnati Research Council,1977, $2,000 The Chemistry and Mechanism of Action of the Radiopharinaceutical Tc(Sn) EHDP, sponsored by the Procter & Gamble Company,1977, $1,500; renewed 1978, $1,500 Quality _ControlofTechnetium Radiopharmaceuticals, sponsored by the Society ofNuclear Medicine,1979, Technetium.porp,$2,000hrin Complexes as Tumor Imaging Agents, sponsored Ly the Society, Ohio Division, 1979-80, $6,000 - .
?Development of 99m Tc Hepatobiliary Imaging' Agents, sponsored by the University of Cincinnati EResearch Council, 1979-80, $2,100 -
Applied Technetium Chemistry, sponsored by Squibb Institute for Medical desearch,1981, $15,000;
; renewed 1982, $7,500 '
LEquilibrium and Dynamic Effects Induced by Coordination of Sulfur, Selenium or Tellurium to Robust Metal Complnes, sponsored by National Science Foundation, 1973-76, $79,600; renewed for 1976-79, S126,000; renewed for 1979-83,$202,000.
Nd A. Deutsch Electrochemistry, Spectroelectrochemistry and Chromatography of Tc Hydroxy- . Diphosphonatecomplexes, sponsored by the Procter & Gamble Company, 1979,52,000; renewed 1980,55,000; renewed 1981,58,000; renewed 1982,58,000; renewed 1983, $18,000 The Development ofIn Vivo and In Vitro Models for the Evaluation of Potential Tc 99m . t Myocardial Imaging Agents, sponsored by Medi+ Physics,1983, S25,000; renewed 1984, , ; I $10,000 NIH SBIR Contract with NeoRx Corp. for Development of Rhenium Radiophannaceuticals, 1986-88, $54,000. Studies on Tc-99m Labeled Psyllium, sponsored by the Procter & Gamble Company,1988,
$5,000.
The Development of Tc-99m POM POM Radiopharmaceuticals, sponsored by Medi+ Physics, 1984-88,S225,000. The Develo ament of Tc-99m Brain Imaging Agents for Use with SPECT, sponsored by Mallinckroc t, Inc., 1985-89,5300,000. Synthesis and Evaluation of Cationic Technetium Complexes as Renal Imaging Agents, sponsored by Kidney Foundation of Greater Cincinnati, co investigator with Pror W. Cacini, 1988-89,54,813. Development of 99m-Tc Myocardial Imaging Agents, sponsored by National Institutes of Health,1977-80, S102,000; renewed for 1982-85, $263,000; renewed for 1985-89,S510,000; renewed for 1989 94,S1,134,700. Development of More Efficacious Tc-99m Organ Imagmg Agents for Use in Nuclear Medicine by Analytical Characterization of Radiopharmaceutical Mixtures, sponsored by the Dept. of Energy, 1980, $91,000; co-investigator with Prof. W.R. Heineman; renewed 1981-84,1985 89, 1990-93. Efficacious Skeletal Imaging Radiopharmaceuticals, sponsored by the National Institutes of - Health, 1980-83, $169,000; co-investigator with Prof. W.R. Heineman, renewed for 1983-87,
$500,000; co-investigator with Professor H.R. Maxon, renewed for 1987-91, $1,100,00.
L Development of 99m-Tc Brain Imaging Agents For Use With SPECT, sponsored by the National Institutes of Health, 1986-90, $391,000. Hazardous Substances Basic Research Program, sponsored by National Institutes of Health, co-investigator with Prof J. Caruso, with Prof. R. Albert, PI, 1989-1993,S600,000. DISSERTATIONSSUPERVJSED l'* '_ con E. Asher, Ph.D., University of Chicago, Chairman
; .: Charles J. Weschler, Ph.D., University of Chicago, Chairman 1976: Lawrence Seibles, Ph.D., University of Cincinati, Co-chairman with G. Dahlgren 1977: Carolyn Lavallee, Ph.D., University of Chicago, Chairman 1977: Gregory J. Kennard, Ph.D., University of Cincinnati, Chairman 1977: I. Kofi Adzamli, Ph.D., University of Cincinnati, Chairman
! 1977: Mary Jane Heeg, Ph.D., University of Cincinnati, Co-chairman with R. Elder i 1977: David F. Rohrbach, Ph.D., University of Cincinnati, Co-chairman with W. Heineman 1980: Thomas C. Pinkerton, Ph.D., University of Cincinnati, Co-chairman with W. Heineman 1981: Karen F. Libson, Ph.D., University of Cincinnati, Chainnan 1981: Dennis L. Nosco, Ph.D., University of Cincinnati, Chairman 1982: Silvia S. Jurisson, Ph.D., University of Cincinnati, Chairman 1982: Michael J. Root, Ph.D., University of Cincinnati, Chairman 1982: Kenneth A. Glavan, Ph.D., University of Cincinnati, Chairman 1982: John D. Lydon, Ph.D., University of Cincinnati, Chairman 1984: Mary E. Noon, Ph.D., University of Cincinnati, Chairman 1985: Jean-Luc Vanderheyden, Ph.D., University of Cincinnati, Chairman 1987 Bruce E. Wilcox, Ph.D., University of Cincinnati, Chairman
- 1987: Walter Hirth. Ph.D., University of Cincinnati, Chairman 1990: Tracy Best, Ph.D., University of Cincinnati, Chairman 1991: Bache Chen, Ph.D., University of Cincinnati, Chairman 1993: Cathy Cutler, Ph.D., University 'of Cincinnati, Chairman I
l . _ - _ _ - - - _ _ - _ _ - _ _ _ _ _ _ _ _ - _ _ _ _ _ _ _ _ - - - _ _ - - - _ ~
l' age 4
' Edward A. Deutsch TilESESSUPERVISED 1975: I. Kofi Adzamli, M.S., University of Cincinnati, Chairman 1977: M. Diane Payne, M.S., University of Cincinnati, Co-Chairman with R. Elder 1977: J.T. Chen, M.S., University of Cincinnati, Chairman 1982: Lee Roccker, M.S., University of Cincinnati, Chairman 1984: Bruce BeCraft, M.S., University of Cincinnati, Chairman 1984: Rudi Kroener, M.S., University of Cincinnati, Chairman 1984: LaNetta Alexander, M.S., University of Cincinnati, Chairman 1988: Johannes Schmidt, M.S., University of Cincinnati, Chairman 1988: Franz Weingart, M.S., University of Cincinnati, Chairman
- 1989: Laura Weyman-Barone, M.S., University of Cincinnati, Chairman 1990: Bernhard Mohr, M.S., University of Cincinnati, Chairman 1990: Jochen Rall, M.S., University of Cincinnati, Chairman 1991: Sebastian Scharner, M.S., University of Cincinnati, Chainnan UNITED STA TES PATENTS (1) USP 4,387,987: Cationic Lipophilic Complexes of 99m Te and Their'Use for Myocardial and Hepatobiliary Imaging. (7/7/83) with K. Glavan.
(2). USP 4,489,054: Cationic Lipophilic Complexes of 99m Tc and Their Use for Myocardial and Hepatobiliary Imaging. (12/18/84)'with K. Glavan. (3) USP 4,778,672: Method ofIsolating Radioactive Penhenate or Pertechnetate from an Aqueous Solution. (10/18/88) with Jean Luc Vanderheyden. ' (4) USP 4,795,626: 99mTc MyocardialImaging Agents Which are Non Reducable In Vivo. (1/3/89) with Jean-Luc Vanderheyden. (5) USP 4,839,467: Radioactive Rhenium Complexed to 2 Hydroxy Isobutyric Acid. (6/13/89) (6) USP 4,895,960: Cyclo Substituted Propylencamine Oxime and Its Use as a Brain Imaging Agent. (1/23/90) (7). USP 4,917,879: 99m-Tc(III) Myocardial Imaging Agents that are Effective in Humans.
.(4/17/90) with K. Libson.
(8) USP 4,925,925: Radioactive Rhenium Ligated to 2-Hydroxy Isobutyric Acid and Method -f Use. 5/15/90) (9) USP 4,935,222: Procedure for Isolating and Purifying Radioactive Ligated Rhenium Pharmaceuticals and Use Thereof and Kit. (6/19/90) with A. Ketring, K. Libson and H. Maxon. (10) ' USP 4,957,728: Kit for Preparing Tc(III) 99m Myocardial Imaging Agents that are Effective in Humans. (9/18/90) with K. Libson.
.-(11) USP 5,00,2,7'4: Technetium (Ill/II) Imaging Agents. (3/26/91).
(12) USP 5,026,829: Cyclo Substituted Propyleneamine Oxime and It_ Use as a Brain Imaging Agent. (1/25/91). (13) USP 5,112,594: Kit for Preparing a Technetium-99m Myocardial Imaging Agent. (5/12/92) with S.R. Woulfe, M.M. Dyszlewski and W.L. Neumann. (14) USP 5,112,595: 99m-Tc(l!!) MyocardialImaging Agenta and Method of Use. (5/12/92) with S.R. Woulfe, M.M. Dyszlewski and W.L. Neumann. 3
Edward A.Deutsch 4
-(15) USP 5,190,742: Device and Method for Car:ying out a Plurality of Sequential .
Transformations of a Substrate. (3/2/93) with K. Libson and F. Lunghi.
-(16)> .USP 5,300,280: Stabilized Radiopharmaceutical Kits. (4/5/94) with M. DeRosch, M. .
Dyszlewski and D. Nosco. , (17) USP 5,320,824:- Radionuclide Labeled Panicles Useful for Radiation Synovectomy. _ (6/14/94) with K. Deutsch, J. Brodack and D. Nosco. (18) USP 5,330,742: Methods and Compositions for Magnetic Resonance Imaging. (7/19/94) with D.A.-Moore. (19) USP 5,344,640: Preparation of Apatite Particles for Medical Diagnostic Imaging. (9/6/94) with W. Cacheris, K. Deutsch, W. Ralston, D. White, S. Woulfe, D. Nosco, R. Wolfangel, J. Wilking, R. Wolfangel, J. Wilking and L. Meeh. 1 (20) USP 5,364,953: High Relaxivity, Paramagnetic, Metal Chisters for Magnetic Resonance l Imaging. (11/15/94) with J. Beaty and D. Nosco. (21) USP 5,382,388: Process for the Pre ' Generators. (1/17/95) with dt and G. Ehrhbaration of Rhenium 188 and R. Wolfangel. '
. (22) USP 5,384,113: Stabilizers to Prevent Autoradiolysis o# Radiolabeled Peptides and ,
Proteins. (1/24/95) with J. Brodack, M. DeJong, W. Goedemans and K. Miller. ! (23) USP 5,407,659: Treated Calcium /oxyanion-containing Particles for Medical Diagnostic Imaging. (4/18/95) with K. Deutsch, D. Nosco, W. Ralston, D. White, J. Wilking, R. Wolfangel and S. Woulfe. (24) USP 5,417,958: Heavy Metal Clusters as Imaging Agents. (5/23/95) with K. Deutsch I and D. Nosco.
)
(25) USP 5,458,870: Compositions for Magnetic Resonance Imaging Using a Manganese Oxalate. (10/17/95) with D. Moore. (26) - USP 5,464,934: Treated Apatite Particles for X-Ray Diagnostic Imaging. (11/21/95) with ! K. Deutsch, W. Cacheris, W. Ralston, D. White, D. Nosco, R. Wolfangel, J. Wilkins, L.- Mcch and S. Woulfe. 1 (27) USP 5,595,724: Treated Calcium /oxyanion containing Particles for Medical Diagnostic Imaging, (1/21/97) with K. F. Deutsch, D. L. Nosco, W. H. Ralston, D. H. Wnite, J. B. Wilking, R. G. Wolfangel, S. R. Woulfe, W. P. Cacheris and L. Meeh. _(28) _ USP 5,609,850: Treated Apatite Particles for Ultrasound Imaging. (3/l1/97) with K.F. Deutsch, W.P. Cacheris, W.H. Ralston, D.H. White, D.L Nosco, R.G. Wolfangel, J.B. Wilking, L Meeh and S.R. Woulfe
. (29) Dietary Calcium / phosphorus Composition. Pending.
' (30) Treating Arthritis by Radiation Synovectomy. Pending.
I
- . _ . . _,u. , _ _ . . . _ - _ _ _ - - . . - . , _ _ _ _ _ _ -_____._ _ _ _ _ . . . . _ _ _
. . _ . . . ., . u , -
Edward A.Deutsch PUBUSHED ABSTRACTS (1) Development of a Tc 99m Myocardial Imaging Agent to Replace TI-201. J. Nucl. hid., H, P56 (1980).- With K.A. Glavan, D.L. Ferguson, S.J. Lukes, H. Nishiyama and V.J. Sodd. (2) In Vivo Evaluation of Components of a Technetium HEDP Radiopharmaceutical Mixture .
- Separated by High Performance Liquid Chromatography. J. Nucl. hitd., H, P12 (1980),
With D.L. Ferguson, T.C. Pinkerton and W.R. Heineman. (3) - Development of a Tc 99m Myocardial Imaging Acent to Replace TI 201: Part II -- Tc-DMPE. J. &ql. hied., H. PSI (1981). With V.J. Sodd, K.L. Scholz, D.L. Fortman, . H. Nishiyama, K.A. Glavan and W.C. Bushong.
- (4) Preparation of"No Carrier Added" 99m Tc Complexes. Trans. Am. Nucl. Eqq., H. 55 ,
(1981). With W.R. Heineman and J.P. Zodda. (5) Electrochemical Studies on Cationic 99-Tc Complexes, the 99m-Tc Analogues of Which are Potential Myocardial Imaging Agents. Clin. Sql. Med.,6, P149 (1981). With K. Libson.
- (6) Synthesis, Characterization and Calcium Affinity of Coordinated Diphosphonate Complexes. Possible Models for the Action of Bone Imaging Agents. Clin Suql. Med.,
6, P151 (1981) With S. Jurisson. (7) Chemistry and Preparation of the Potential MyocardialImaging Agent r [""'Tc(dmpe)2Clg (Tc-99m DMPE). J. Nucl. Med., H, P9 (1982). With K. Libson, j J.-L. Vanderheyden, D.L. Nosco, V.J. Sodd and H. Nishiyama. (8) Tc 99m DMPE as a Resting Myocardial Imaging Agent. J. Nucl. hid., H, P12 (1982). With H. Nishiyama, R.J. Adolph, V.J. Snda, K. Libson, S.J. Lukes, M. Gabel, M.C. Gerson, J.-L. Vanderheyden and E.L. Saenger. 1 (9) Tc-99m DMPE as a Functional Myocardialimaging Agent. J.Nucl. Med., H, P12 4 (1982). With H. Nishiyama, V.J. Sodd, R.J. Adolph, K. Libson, M.C. Gerson, J.-LJ Vanderheyden, M. Gabel, S.J. Lukes and E.L. Saenger. (10) Tc-99m DMPE as a Myocardial Imaging Agent: Organ Distribution and Dosimetry in the Rat. J. Nucl. Med., H, P87 (1982). With V.J. Sodd, K.L. Scholz, L.W. Grossman, D.L. Fortman, P.J. Robbins, H. Nishiyama, R.J. Adolph and K. Libson. (11) Development and Use of a New Tc-99m Myocardial Perfusion Agent - DMPE, In
" Proceedings of the Third World Congress of Nuclear Medicine and Biology", Pergamon Press, Vol. 2, C. Raynaud, ed., p. 2255 (1982). With V.J. Sodd, H. Nishiyama, R.J.
Adolph, L.W. Grossman, K.L. Scholz, K. Libson, D.L. Fortman, J.-L. Vanderheyden i and E.L. Saenger.' (12) Synthesis and Characterization of[99m-Tc(dmpe)g A Potential Myocardial Imaging Agent. J. &gl. hid., M, P9 (1983). With J.-L. Vanderheyden, K. Libson and A.R.
- Ketring. -
The Noah's Ark Experiment. A Search for a Suitable Animal Model for the Evaluation of 4 (13)~ Cationic Tc-99m MyocardialImaging Agents. J.Nucl. hjed.,M, P9(1983). With A.R.
- Ketring, K. Libson, J.-L. Vanderheyden, V.J. Sodd, H. Nishiyama and S. Lukes.
(14) Preparative Control, HPLC Analysis, and In Vivo Evaluation of Components of a Technetium-MDP Radiopharinaceutical Mixture. J. Nucl. Med., M, P23, (1983). With
~
K. Libson, W.R. Heineman, S. Tanabe and J.P. Zodda.
- + - - - - ,.--v-,v. . - , , ,c ,, , - - ,,,,y. - --,~ , , , - , , - - - --
Pege 7 - - Edward A. Deutsch - (15) Re-186 HEDP: A Potential Therapeutic Bone Agent. J. Nucl. Med., H, P23,(1983). . With K, Libson, W.R. Heineman, S. Tanabe and J.P. Zodda. (16) Synthesis and Characterization of Tc-8-Quinolinolates. Potential Brain Imaging Agents. J. N9cl. c Md., E, P128, (1983). With B.E. Wilcox. (17) 186-Re HEDP: A Potential Therapeutic Bone Agent. Nu.q]. Md.,21,81 (1984). With J. Weininger and A.R . Ketring. (18) Recent Developments in Technetium-99m Labeled Radiopharmaceuticals. Nuklearmedizine. Swr 1. (Stuttean). 29,113 (1984). (19) Biological Mechanism of Action of the Potential Myocardial Perfusion Imaging Agent II- ["*Tc(DMPE)2Cl ]'. J. Engl. Med.,26, P18 (1985), With J.-L. Vanderheyden. (20) - Evaluation in Man and Dog of Three New Cationic Technetium -99m Complexes for Myocardial Perfusion Imaging. J. Hugl. Md.,26, 824 (1985). With P. Gerundini, A. Savi, M.C. Gilardi, L. Zecca, W. Hirth, K. Libson and F. Fazio. (21) Three New Tc-99m Complexes as Myocardium Perfusion Tracers. Fat. J. Nucl. Med., H, A39(1985). With P . Gerundini, A. Savi, M.C. Gilardi, L. Zecca, W. Hirth, K. Libson and F. Fazio. , (22) Three New 99m Tc-Agents for Myocardial Perfusion Studies 1. Engl. Md. M. Sci., ' 22,86 (1985). With P. GerurJini, A. Savi, M.C. Gilardi, L. Zecca, M. Matarrese, W. Hirth, K. Libson and F. Fazio. (23) Tc(V) Com alexes with Schiff Base Derivatives of Glucosamine. J. Nucl. Med. M. sei., 2.9,195 (1935). With A. Duatti, A. Marchi, L. Magon and J.-L. Vanderheyden. (24) Evaluation of Three 99m-Tc Complexes as Myocardial Perfusion Agents. J. Mugl. u M. Egi.,22,198 (1985). With P. Gerundini, A. Savi and F. Fazio. (25) Electrochemistry of Technetium Radiopharmac'euticals J. Engl. Med. M. Esi.,22c 199 l (1985). With W.R. Heineman and R.B. Scott. (26) 99m Tc-Radiopharmaceuticals for Brain Perfusion Imaging J. Hugl. Med. M. Egi.,29, 108 (1985). 4 ith M. Neves and K. Libson. (27) 186-Re(Sn)HEDP -- A New Agent for Diagnosis and Treatment of Metastatic Carcinoma to Bone. J. Nngl. Md.,22,948 (1986). With H.R. Maxon, K. Libson, C. Williams, S. Thomas, S. Lukes and I.W. Chen. (28) Development of Nonreducible 99m-Technetium (lll) Cations as Myocardial Perfusion Imaging Agents. 'J. Engl. Med.,22,894 (1986). With J.-L. Vanderheyden, P. Gerundmi, K. Libson, W. Hirth, A. Savi, L, Zecca and F. Fazio. (29) Determination of Cobalt (II) in 2<(5-cyanotetrazolato)pentaamine-cobalt (lll) perchlorate. Engru En. Ahlt., H,3361 (1986). With R.J. Schumacher, and N.E. Brown. (30) 186-Re-(Sn)-HEDP, A n audiopharmaceutical fci the Treatment of Metastatic Bone Cancer. J. Musl. Med. M. Es]., H, 60 (1987). With K. Libson and H.R. Maxon. (31) Re-186(Sn)-HEDP -- Results of Diagnostic Studies and Therapeutic Implications in Five Patients with Skeletal Metastases. J. Nucl. Med.,23,626 (1987). With H.R. Maxon, S.R. Thomas, S.J. Lukes, K. Libson, C.C. Wiliams and S. Ali.
, .Page 8 Edward A. Deutsch
, (32) 99m-Tc DADS Amido-Fatty Acids as Potential Myocardial Metabolism Imaging Agents.
J. Nucl. Med , H,935 (1988). With T. Kelso, J L. Vanderheyden, J.Bugaj, L. Gustavson, and A. Fritzberg. ('3) 3 Tc-99m Complexes of a,ot-Disubstituted a-Hydroxy Carboxylic Acids. J.E_ue.l. Med., H,934 (1988). With F. Colombo, M. Matarrese, J. Bugaj, P. Gerundini and F. Fazio. (34) Mechanism of Action of Tc-99m Renal Agents Based on Sulfur-Donating Chelates. J. Nucl. Ed. E, 801 (1988). With M. Matarrese, F. Colombo, J. Bugaj, P. Gemndini and F. Fazio, (35) Model Studies for Direct Radiothenium Labeling of Monoclonal Antibodies. J. Nucl. Med. L9,847 (1988). With M. Kwiatkowski, J L. Vanderheyden, I.K. Adzam:i, A. Srinivasan and A. Fritzberg. (36) Initial Experience with 186-Re(Sn)-HEDP in the Treatment of Painful Skeletal Metastases, J. Nucl. Med., H, 776 (1988). With H.R. Maxon, S.R. Thomas, J.S. Moulton, L.E. Schroder, K.F. Libson, M. Soldano, C.C. Williams and D.D. Cummings. (37) Studies on the Mechanism of Action of I86-Re(Sn)-HEDP, A New Agent for the Treatment of Painful Skeletal Metastases. J. Nucl. Med., M,732 (1989). With A. Roodt, K. Libson, C. Cutler, S. R. Thomas and H. R. Maxon. (38) EXAFS Structural Studies on Technetium and Rhenium Diphosphonates. J. Nucl. Med., ' E,732 (1989). With J.L. Martin, J. Yuan, K. Libson, R.C. Elder and W.R. Heineman. (39) A New 99m-Tc PAO Cerebral Perfusion Agent With In Vitro Strbility. J. Nucl. Med., M,742 (1989). With F. Colombo, F. Lunghi, G. Deleide, M. Matanese, C. Bonino, Z. Jiang, K. Libson, J. Belletire and F. Fazio. (40) Comparative Rates of Ligand Substitution on Technetium (V) and Rhenium (V) Complexes. J. Nucl. Med., M,743 (1989). With K. Libson, L. Helm, C. Cutler, and A. Merbach. (41) The Development of a New Class of Mixed Ligand (Phosphine /Fhiolato) 99m-Tc Radiopharmaceuticals. J. Nucl. Med., E 772 (1989). With G. Peake, M. El-Etri, N. Razumenic and N. Godoy-Sanchez. (42) Evaluation of a New Tracer for Cerebral Perfusion Studies: Tc-99m d,1 CBPAO. Preliminary Results in Humans. J. Nuct Med., M,831 (1989). With C. Messa, F. Zito, C. Rossetti, F. Colombo, M. Matarrese, G. Taddei, G. Lucignani and F. Fazio. (43) 186-Re(Sn).HEDP Palliation of Painful Skeletal Metastases From Hormonally Resistant Prostate Cancer. J. Nucl. Med., M 837 (1989). With H.R. Maxon, S.R. Thomas, V.S. Hertzberg, L. E. Schroder, K.F. Libson, R.C. Samaratunga, C.C. Williams and J.S. Mouhon. (44) Evaluation and Characterization of Zirconium-Tungstate Gel 188-W/188-Re Generators for Clinical Use. J. Nucl. Med., E, 849 (1989). With A. Roodt, F. M. Su, G. Ehrhardt, J.- L. Vanderheyden. K. Libson and A. Fritzberg. (45) The Inorganic Chemistry of a New Class of Mixed Ligand Technetium Complexes of Relevance to Nuclear Medicine. J. Nuc'. Med., M. 936 (1989). With T. Konno, K. Okamoto, M. J. Heeg, W. R. Heineman, J.F. Kirchhoff and J. Peake. (46) Rapid Installation and Start-up of a Clinical PET / Cyclotron Facility. J. Nucl. Med. A_ll. Ecl.,33,97 c (1989). With F. Colombo, M. Matarrese, F. Sudati and F. Fazio.
~ ~ ~ ~ ~
Pagi9 - - Edwad A.Deutsch . (47) quality Control of PET Radiopharmaceuticals Produced by a Medical Cyclotorn. J. - hu_ql. Mrd. M. M., H,97 (1989). With F. Colombo, M, Matarrese, F. Sudati, S. Chang and F. Fazio. (48) Development of"*Tc d,bCB-PAO: A New Cerebral Perfusion Agent With More' than Six Hours o"n Vhro Stabilty. J. Eqcj. e Med. M. M., H,98 (1989). With F. Colombo, F. I/ i, G. Daleide, M. Matarrese, C. Bonino, Z. Jiang, K. Libson, J. Belletire and F . jo. (49) Evaluation of""Tc d,1-CB PAO. A New Tracer for Cerebral Perfusion Studies: Preliminary Results in Humans. J. Nucl. Mrd. M. M., H, 161 (1989). With C. Messa, F. Zito, C. Rossetti, F. Colombo, M. Matarrese, G. Taddei, G. Lucignani and F. Fazio. (50) Comparative Chemical and Biological Properties of the RCBF Agents ""Tc d,1-CB-PAO and ""'Tc d,1-EM-PAO, J. Nuc. Med. M. M., H,278 (1989). With F. Colombo, K. Libson, Z. Jiang, G. Deleide, M. Matarrese, C. Bonino, J. Bellettre, F. Lunghi and F. Fazio. (51) The Inorganic Chemistiy of Technetium and Rhenium as Relevant to Nuclear Medicine. J. NUS). Mrd. M. M., H,279 (l989). (52) Development of New "*Tc Myocardial Perfusion Imaging Agents. J. Nucl. Med. M. M., H,297 (1989). With K. Libson, C. Messa, M. Kwiatkowski, F. Zito, T. Kelso, F. Colombo, M. Matarrese, X. Wang, G. Fragasso and F. Fazio. , (53) Kinetics and Mechanism of Ligand Substitution on Analogous Technetium (V) and Rhenium (V) Complexes. J. Nucl. Med. M. M., H, 297 (1989). With K. Libson, L. Helm, A. Roodt, C. Cutler, A. Merbach and J. C. Sullivan. (54) Preliminary Comparison of the RCBF Tracers "*Tc d,1 HM-PAO and ""Tc d,1-CB-PAO in Human Volunteers J. Nucl. Med. M. M., H, 305 (1989). With C. Messa, F. Zito, F. Colombo, C. Rossetti, G. Taddei, G. Lucignani and F. Fazio. (55) Synthesis, HPLC Characterization, and Rat Biodistribution of Stable, Neutral, Lipid-soluble ""Tc Phosphine Carboxylate Complexes. J. Nucl. Med. M. M., H, 313 (1989). With F. Refosco, U. Mazzi, A. Moresco, and M. Nicolini. (56) '"Re(Sn)-HEDP for the Treatment of Painful Osseous Metastases: Initial Clinical Ex aerience. J. Nucl. Mrd. M. M., H. 328 (1989). With H. R. Maxon, L. E. Schroder, S. 3. Thomas, V. S. Hertzberg, R.C. Samaratunga, K. F. Libson, C. C. Williams, J. S. Moulton and H. J. Schneider. (57) New ""Tc Myocardial Perfusion Imaging Agents. J. Nucl. Med., H, 747 (1990). With K. Libson, T. Best, F. Zito, M. Kwiatkowski, F. Colombo, M. Matarrese, G. Fragasso and F. Fazio. (58) A New Nonreducible Tc 99m Myocardial Perfusion Tracer: Human Biodistribution and Initial Clinical Ex 3erience. J. Nucl. Med., H, 834 (1990). With C. Rossetti, T. Best, G. Paganejli, G. Vano i, F. Zito, F. Colombo, G. Fragasso, G. Lucignani, K. Libson and F. Fazio. (59) Analysis by High Pressure Liquid Chromatography of Rhenium-186 HEDP,:. New Therapeutic Radiopharmaceutical. J. Nucl. Med., H, 768 (1990). With D. M. Pipes, K. M. Miller, R. G. Wolfangel, G. D. Pilcher and J. R. Coveney. (60) New Mixed Tc/Sn Complexes: Relevance to Nuclear Medicine. J. Nucl. Med., H,807 (1990). With M. Marmion and K. Libson.
Page T@ Edward A. Deutsch
.(61) Evaluation of Five New "*Tc Myocmdial Perfusion Tracers. Etg.1. Musl. Md. .L6, 537(1990). With K. Libson, T. Best, F. Zito, M. Kwiatkowski, F. Colombo, M.
Matarrese, R. M. Moresco, G. Fragasso and F. Fazio. (62) lluman Biodistribution and Initial Clinical Evaluation of a New Myocardial Perfusion Tracer: ""Tc Q3. Eur.1. Mugj. W.,15,541(1990). With C. Rossetti, T. Best G. Paganelli, G. Vanoli, F. Zito, F. Colombo, G. Fragasso, G. Lucignani, K. Libson and F. Fazio. (63) A New and Rapid Method for the Determination of Technetium > in Environmental Sam ales Using ICP-MS. Proceedings of the 200th American Chemical Society Meeting, Wasaington, DC, August 26 31,1990. Alatr. Eap. AC.S. 200(1-2), ENVR-94 (1990). With L.S. Chang, J. Caruso, K. Wolnik, and D. Heitkemper. (64) Chemistry of a New Class of"*Tc Myocardial Perfusion Agents with O atimized Imaging Properties.1. Nucl. Med., H,925 (1991). With M. Marmion, k. Kwiatkowski, D. Nosco, S. Woulfe, W. Neumann, G. Grunanon, J. MacDonald, L.S. Chang, K. Deutsch, F. Colombo, C. Rossetti, F. Fazio, et al. (65) Gallium Tris (salicylaldimine) Complexes Derived from Functionalized Tripodal Triamines.1. Mu_cl. c Mrd., H,944 (1991). With M.A. Green, C.J. Mathias, W.L. Neumann and M. Janik. (66) The Chemistry of Two New Classes of Agents for Radiation Synovectomy.1. Nucl. ' Mrd., H,945 (1991). With K. Deutsch, L. Chinen, M. Chinol, S. Vallabhajosula and S.J. Goldsmith. (67) Evaluation of New Radiopharmaceuticals for Radiation Synovectomy (RS).1. Mu_ql. Mrd., H, 963 (1991). With M. Chinol, S. Vallabhajosula, S.J. Goldsmith, K. Deutsch and L. Chinen. (68) Micros:3heres of Human Scrum Albumin Labelled by a Specific Linker Technology for Use in ladiation Synovectomy.1. Nucl. Med., H,964 (1991. With G. Ehrhardt, K. Zinn, W. Jia, D. Day, E. Erbe, K. Deutsch, L. de La Fourniere and G. Gr'unmon. (69) Q12: A New "*Tc Myocardial Perfusion Agent With Optimized Imaging Properties. Evaluation in Humans.1. Nucl. Meq., H. 1007 (1991). With C. Rossetti, G.Vanoli, G. Paganelli, M. KwLtkowski, F. Zito, F. Colombo and F. Fazio. (70) A New Synthetic Route to Multidentate-N,S Ligands. Comparative Biodistributions of V [""Tc O-DADS]- Analogs which Contain 5,5,5- and 5,7,5-Membered Chelate Ring Systems. J. Encl. c Med., H. 1016 (1991). With D. Stepniak-Biniakiewicz and B. Chen. (71) EXAFS and WAXS Structural Characterization of 186-Rhenium-HEDP, A New Agent for the Palliation 'of Pain of Metastatic Bone Disease.1. Nucl. Med., H, 1089 (1991). With D.W. Pipes, J. D'Amore, K. Deutsch and R.C. Elder. (72) The Synthesis of Analogous N22 0 , N20S and N2S2 Schiff Base Ligands for Use in Radiopharmaceutical Imaging Agents. J. Nucl. Med., H,1101 (1991). With S.R. Woulfe, T.J. Dunn, M.E. Marmion, J.R. MacDonald and M.M. Rogic. (73) Synthesis and Biological Characteristics of Tc-99m(L-L) Complexes Containing Ether Analogs of DMPE.1. Nucl. Med., H, 1102 (1991) With E.C. Liste. (74) Design and Synthesis of New Preorganized Hexachelating N,0 P2 Ligand Systems for MetalBased Radiopharmaceutical Applications.1. Nucl. Med.,2E,1103 (1991). With W.L. Neumann, J.W. Brodack, R. Rajagopalan. M.M. Rogic and T.J. Dunn.
Page11 Edwmd A. Deutsch (75) New Radio?harmaceuticals for Radiation Synovectomy: Safety Studies in Normal - Rabbits and Rabbits with Antigen Induced Arthritis (AIA). h.1. Mc_1. Med., H. 529 (1991). With S. Vallabhajosula. M. Chinol, S.J. Goldsmith. K. Deutsch and L. Chinen. (76) Development of an in.111 Labeled Somatostatin Analogue: Octreoscan 111. Fatt.1 Nucl. Med., H,532 (1991). With M. de Jong, K.M. Miller, J. Brodack and G.J. Ensing. (77) Synthesis and Biodistribution of a New Class of"*Tc Myocardial Perfusion Agents with Optimized Imaging Pro aerties. Fau.r. l. Nucl. Med., H,537 (1991). With M. Marmion, M. Kwiatkowski, J. Nosco, S. Woulfe, W. Neumann, G. Grummon, J. MacDonald. L.S. Chang, K. Deutsch, F. Colombo, C. Rossetti, F. Fazio, et al. (78) Evaluation in Humans of a New Tracer with Optimized Properties for Myocardial Perfusion Imaging: [Tc 99m] Q12. F,ur.1. Nue :. Med., H,540 (1991). With C. Rossetti, G. Vanoli, G. Paganelli, M. Kwiatkowski, F. Zito, F. Colombo and F. Fazio. (79) Studies on the Chemical and Biological Properties of Mn-52m. Eur.1. Nucl. Med., H, . 637 (1991). With M. Matarrese, R.J. Nickles, O.T. De Jesus, F. Colombo, F. Fazio. (80) Metabolic and Kinetic Evaluation of the Potential RCBF Indicator [Tc-99m]CB-PAO. h.1. Nucl. Med., H,671(1991). Wtih R.M. Moresco, G. Lucignani, C. Rossetti, T. Best, F. Colombo and F. Fazio. (81) Mixed Complexes of Technetium and Tin.1. Labelled Comod. Radionharm., M,9 (1991). With M. Marmion and K. Libson (82) A New 99m-Tc Radiotracer Named Q-12: A Myocardial Perfusion Agent with Optimized Imaging Properties.1. Nucl. Med. Bjol., o M, 114 (1992). With F. Colombo, M. Marmion, K. Deutsch, A. Carpinelli, M. Kwiatkowski, R. Casati, C. Bonino, C. Rossetti and F. F,uio. (83) The Development of Nonreducible "*Tc Myncardial Pe. fusion Agents with Optimized Imaging Characteristics.1. Nucl. Med. Biol., M, 157 (1992). With M. Mannion, K. Deutsch, G. Grununon, D. Nosco, F. Colombo, A. Carpinelli, R. Casati, C. Bonino, C. Rossetti and F. Fazio. (84) Biodistribution in Humans of a New Tracer for Myocardial Perfusion Imaging: 99mTc-Q12,1. Nucl. Med. Biol., M,194 (1992). With C. Rossetti, G. Vanoli, G. Paganelli, M. Kwiatkowski, F. Zito, C. Di Leo, F. Colombo, A. Carpinelli, C. Bonino, F. Lunghi and F. Fazio. (85) Kit Development for the Tc-99m MyocardialImaging Agent TechneCard 1. Nucl. Med., H, 850 (1992). With M.A. De Rosch, J.W. Brodack, G.D. Grummon, M.E. Marmion, D.L. N.osco, and K.F. Deutsch. (86) Comparative Biodistributions of 186-Re,96-Tc,153-Sm and 117m-Sn Bone Seeking Agents: Mechanistic Implications.1. Nucl. Med., H, 899 (1992). With C. Cutler, K Schaab, A. Roodt, S.C. Srivastava, and L.F. Mausner. (87) Characterization of the Two Diasteromers of Octreoscan-111, An In-111 Labeled Peptide for Use in Cancer Imaging.1. MucJ. Med., M,900 (1992). With R. Albert, K. Miller, R. Chong, W. Hirth, J-L. Vanderheyden and K. Deutsch. (SS) Technetium-99m 2 GAM, A New Agent for Renal Imaging Evaluation in Humans. 1, Nucl. Med., H, (1992). With L. Gianolli, F. Dosio, M. Matarrese, D. Stepniak-Biniakiewica. A. Savei, M. Vaghi, G. Coiombo and F. Fazio.
. ragg m Edward A. Deutsch (89) Studies on Ho-166 Labelled Hydroxyapatite: A New Agent for Radiation Syaovectomy.
- 1. Muc_j. hitd., D. 937 (1992). With S. Shortkroff, A. Mahmood, C.B. Sledge, A.G.
Jones, J.W. Brodack, L.K. Chinen and K.F. Deutsch
'(90) . Studies on the Radiolabelling of Hydroxyapstite Particles for Use as Radiation Synovectomy Agents. J. Mycf. Med., H,980 (1992). With J.W. Brodack, L.K. Chinen and K.F. Deutsch.
(91) Preparation and Evaluation ofI-123 Labeled Hirulog, A New Potential Agent for Blood Clot Imaging. J. Nuct. Med., H,981(1992). With L. de la Fourniere, B.H. Chao, J. Maraganore, A. Lasdun, J L. Vanderheyden and K. Deutsch. (92) Evaluation of New Ligands Related to Both MAG 3 and Hip Tc Renal Function Agents. J. Nucl. Med., H,988 ith D.(1992). % puric Acid as Potent Stepniak-Diniakiewicz, H. Vavouraki, S. Mastrostamatis and E. Chiotelis. (93) Relationship cf Tc-99m Q12 Activity to Myocardial Blood Flow in the Canine Heart. J. Musl. hiid., H, 993 (1992). With M.C. Gerson, R.W. Millard, N. Roszell, M. Gabel, D. Blankenship, W. Mallin, L.C. Washburn, D. Biniakiewicz and R.A. Walsh. (94) Kit Development of Octreoscan-111, An In 111 Labeled Somatostatin Analog fo: Use in Cancer Detection. J. Nucl. Med., H,1025 (1992). With K. Miller, W. Goedemans, M. deJong, J L. Vanderheyden, R. Chong, J. Brodack, G. Ensing and K. Deutsch . (95) Metal Ions in Nuclear Medicine. Radioactive Complexes of Technetium and Rhenium for Diagnosis and Therapy. Proceedings of the 203rd American Chemical Society National Meeting, San Francisco, CA, April 5-10,1992. Abstr. Ean. ACS,201(1-3), BTEC37 (1992). (96) Biodistribution and Preliminary Clinical Evaluation of a Kit Formulation for the New Myocardial Imaging Agent "*Tc Q12. Eut. J. Nucl. Med., B,596 (1992). With C. Rossetti, G. Vanoli, G. Paganelli, A. Carapinelli, F. Colombo, C. Bonino, M. DeRosch, M. Marmion, J. Brodack, K. Deutsch and F. Fazio (97) In Vivo Evaluation of a New Renal Mass Agent. Eu.. r l. Nucl. Med., H,617 (1992). With L. Gianolli, F. Dosio, M. Matarrese, D. Stepniak-Biniakiewicz, A. Savi, M. Vaghi, F. Colombo, and F. Fazio. (98) A New Cationic Agent (Q-12) for Myocardial Perfusion Studies. Eu.r. J. Nucl. hied., D, 739 (1992). With F. Colombo, M. Marmion, K. Deutsch, A. Carpinelli, M. Kwiatkewski, R. Casati, C. Bonino, C. Rossetti and F. Fazio. (99) Evaluation of the In Vivo Stability and Safety of a New Agent for Radiation Synovectomy: Holmium-166 Hydroxyapatite. Arthritis Rheum., M (Suppl . 9), S200 (1992). With S. Shortkrcff, A. Mahood, A.G. Jones, C.B. Sledge, J.W. Brodack, L.K. Chinen, and K.F. Deutsch. (100) Biodistribution in Humans and Preliminary Clinical Evaluation of a New Tracer with Optimizest Properties for Myocardial Perfusion Imaging: [99mTc]Q12.1. N_ucl. Med.
.Ilt91., M, 29 (1992). With C. Rossetti, G. Paganelli G. Vanoli, C. Di Leo, M.
Kwiatkowski, F. Zito, F. Colombo, c' Boaina, A. Carpinelli and F. Fazio. (101) Myocardial Kinetics of Tc 99m Q-12 in Dogs. Circulation, M, I-708 (1992). With M.C. Gerson, R.W. Millard. N.J. Roszell, M. Gabel, D.C. Blankenship. W.H. Mallin, L.C. Washburn, D. Biniakiewica and R.A. Walsh.
~~ ' ~ ~ . . _ . -__.
~ Page 13 '
Edward A. Deutsch , (102) Synthesis, Labeling with Tc-99m and Biological Evaluation of New Ligands Related to - Both MAG 3 and Hippuric Acid. Proc. IXth Intemational Symposium on Radiopharma-ceutical Chemistry, Paris,6-10 April,1992, Conservatoire National des Arts et Metiers, 292 rue Saint Martin,75003 Paris, J. Labelled Compd. Radionharm.,)_2,94 (1993). - With D. Stepniac Biniakiewicz, H. Vavouraki, S. Mastrostamatis and E. Chiotelis.' (103) EXAFS Structural Characterization of Solutions of186 Rhenium HEDP, A Therapeutic Agent for Metastatic Bone Cancer. J. Nucl. Med., M,38P (1993). With D. Pipes, J. Yuan, B. Helmer, K. Deutsch and R.C. Elder. (104) Comparison of Tc-99m Q3 and TI-201 for Det:ction of Coronary Disease in Man. J. Nus]. Mr.d., M,120P (1993). With M.C. Gerson, J. Lukes. D. Biniakiewicz, L.C. Washburn, D.J. Lenihan, R.C. Elder and R.A. Walsh. (105) Organ Uptake & Biodistribution Studies of Tc-99m-Q3, a New Myocardial Imaging Agent. J. Nucl. Med., M,156P (1993). With R.C. Rohe, S.R. Thomas, D.D. Cummins, M.C. Gerson and H.R. Maxon. (105) Preparation of Tc 99m-Q-3, A New MyocardialImaging Agent, for Clinical Studies. J. N_ugj. Med., M,248P (1993). With D.S. Biniakiewicz, L.C. Washburn, M.C. Gerson, R.C. Elder and H.R. Maxon. (107) Histologic Evaluation and In Vivo Stability of a Potential New Agent for Radiaition Synovectomy: Holmium-166 Hydroxylapatite. J. Cell. Biochem. Sunnl. Q, jl,152 (1993). With J.W. Brodack, L.K. Chinen and K.F. Deutsch. ' (108) Identification of Myocardial Perfusion Defects using ""'Tc Q12. Fag. J. Nucl. Med., ;LO, 860 (1993). With C. Rossetti, G. Vanoli, A. Carpinelli, G. Paganelli, C. Bonino, F. Colombo and F. Fazio. (109) Myocardial Uptake & Kinetics of Tc-99m Q3 in Dogs. Proceedings of the First International Congress of Nuclear Cardiology, Cannes, France, April 25-28,1993. Abstract 602 (1993). With M.C. Gerson, R.W. Millard, A.J. McGordon, M. Gabel, L.C. Washburn, D. Biniakiewicz, R.C. Elder and R.A. Walsh. (110) Comparison of Tc-99m Q12 and TI 201 Imaging for Detection of Angiographic Coronary Artery Disease. J. Am. Coll. Card.,231,255A (1994). With M.C. Gerson, J. Lukes, D. Biniakiewicz, C. Fortman, L.C. Washbum and R.A. Walsh. (111) - Myocardial Kinetics of Tc-99m Q12 in Dogs. Circulation (Sunnl. D,85,I-708 (1994). With M.C. Gerson, R.W. Millard, N.J. Roszell, M. Gabel, D.C. Blankenship, W.H. Mallin, L,C. Washburn and D. Biniakiewicz. (112) Novel Chemistry Used in the Cyclodextrin-Stabilized TechneScan@ Q12 kit.1. Nucl. Med., H,139P (1994). With J.E. Bugaj, M.A. DeRosch, M.E. Marmion, R.H. Quint and K.F. Deutsch. (113) Radiopharmaceutical Development of TechneScan Q12 . J. Nucl. Biol. Med., M,455 (1994). With M. Marmion, M. DeRosch, M. Bushman, R. Wolfongel, E. Webb and K. Deutsch. (114) Diagnostic / Therapeutic Radioisotope Pairs; A Comparison of 99m-Tc/186-Re and Il-In/90 Y Targeted Radiopharmaceuticals. J. Nucl. Diol. Med., E,457 (1994). With K. Miller. (115) NMR Shielding Effects Operated by the Metal Onto Analogous Technetium and Rhenium Complexes. J. Nucl. Biol. Med., J_8,432-433 (1994). With F. Tisato, F. Refosco and M. Nicolini.
Egelf0 Edward A. Deutsch (1l'6) Nuclear, Chemical and Mechanistic Considerations in the Use of "'"'Sn(4+) DTPA Relative to '"Re HEDP and Other Agents for Bone Pain Therapy.1. Engj. Hici. hhd., M,465-466 (1994). With S. C. Srivastava, G.E. Meinken, L.F. Mausner, C. Cutler and H.L. Atkins. (117) Comparison of Tc-99m Q12 and TI 201 Imaging for Detection of Angiographic Coronary Artery Disease, l. Am. Coll. Cardiol.,915-86 (1994). With M.C. Gerson, J. Lukes. D. Biniakiewicz, C. Fortman, LC. Wahsburn and R.A. Walsh. (118) Non Reducible Mixed Ligand Tc(III) Cations (Q Complexes) are Recognized as Transport Substrates by the Human Multidrug Resistance (MDR) P-Glycoprotein. J. Euqj. hhd., M,130P (1995). With C.L. Crankshaw, M. Marmion, B.D. Burleigh, and D. Piwinica-Worms. (119) Hydroxyapatite Particks for Radionuclide Synovectcmy in an Antigen Induced Arthritis Rabbit Model. Combined Orthopaedic Research Societies Meeting, Nov. 6 8,1995, San Diego, CA. With S. Shortkroff, A. Mahmood, C.B. Sledge, J. Brodack and K. Deutsch. (120) Effects of Stability and Lipophilicity on the Brain Extraction and Retention of 99m-Tc-PAO complexes.1. Labelled Comnd. Radionharm., H,785-787 (1995). With C. Cutler, Z. Jiang, B. Chen, Y. P. fiing, W. R. Heineman, T. Mains, F. Tisato and C. Seliskar (121) Mixed Ligand Tc-99m(III) Cations (Q-complexes) are Recognized as Transport Substrates by the Human Multidrug Resistance P-Glycoprotein. Proc, Amer. Assoc. Cang. Be1., B, 317 (1996). With G. Luker, C. L. Crankshaw, M. Marmion, D. B. Burleigh and D. Piwinica-Wonns. PUBLICATIONS (5) Studies on the Acetatopentanquodnomium (Ill) lon, IncIg. Chem.,2,1532 (1968). With H. Taube. (2) The Nucleophilicity of Vitamin B12s,1. Amer. Chem. Srs. 9A 2441 (1968). With G.N. Schrauzer and R.J. Windgassen. (3) Acetatopentaaquochromium(lll) lon. Djss. Abstr. H., M,2753 (1968). (4) Reaction of Cobalt (1) Supemucleophiles. The Alkylation of Vitamin B12s, Cobaloximes(l) and Related Compounds,1. Amer. Chem. Soc.,9].,3341(1969). With G.N. Schrauzer. (5) The Oxidation of Mercury (I) by Neptunium (VII),1. Amer Chem. Sac.,23. 5667 (1971). With M.A. Thom'pson and J.C. Sulhvan. (6) Kinetic Study of the Chromium (II) Reduction of Substituted Glycinatopentaammine cobalt (m)lons,In9Ig Chem ,H, 1965 (1972). With R. Holwerda and H. Taube. (7) Studies on the Chemistry and Structure of the 1,4-Dithioniabicyclo(2,2,2) octane Cation,
- 1. Q.Ig. Chem., E,3481 (1972).
(8) Preparation and Aquation Kinetics of the Pentaaquo(4-thioaniliniumS) chromium (III)lon: Catalysis of Cr-S Bond Breaking by Oxygen and Other Oxidants. InqIg. Chem., H,927 (1972) With L. Asher. (9)- Reinvestigation of Malonaie as an Electron-Transfer Bridge. A Medium Effect, Inore. Chem., H,3133 (1972). With C. Lavallee.
~ Page 15 Edward A. Deutsch , (10). Equilibrium and Kinetic Studies of the Reactions Between Np(III) and the Complexes - (NA),RuGH:] and [(NH ).Ru] in Aqueous Trifluciomethanesulfonate Solutions, 3 mtg. Chem , R, 570 (1973). With D.K. Lavallee. C. Laval'ee and J.C. Sullivan. (11) Noncoordinating Buffers I: Synthesis and Characterization of Water Soluble Derivat'ives of 2,6-Di-1-butylpyridine, J. Otg. Chem., E 1123 (1973). With N.K.V. Cheung. (12) Oxidation of Coordinated Thiol at Carbon Rather Than Sulfur. A Possible Reaction Pattem for the Action of Aldehyde Dehydrogenase, J. Amer. Chem. Soc.,21,2720 (1973). With C. Weschler and J.C. Sulhvan. (13) Reaction of Thiols with the One-equivalent oxidants Np(VI) and Ce(IV) in Aqueous Acidic Media, hetg. Chem., H, 1440(1973). With D.K. Lavallee and J. Sullivan. (14) Pre 3aration and Aquation Kinetics of the Pentaaquo(2-mercaptoethylammonium-S)c 1romium(Ill) lon. Origir. of the ko Term in Rate Laws of the Form -d(In[(H 2O)3-CrX]"')/dt = k, + k,(H'), Inore. Chem., H,2682 (1973). With L. Asher. (15) Synthesis, Characterization, and Aquation Kinetics of Thiolatobis(ethylenediamine) chromium (III) Complexes, Inore. Chem., H,2682 (1973). With C. Weschler. (16) Interactions Between Polynucleotides and Platinum (II) Complexes, Biochem. Bionhvs. Res. Commun., S, 662 (1973). With S. Wherland, J. Eliason an P.B. Sigler. (17) A Kinetic Study of the Reaction Np(VII) + V(IV)* Np(VI) + V(V) in Agueous Perchloric Acid Media, Inore. Chem., H, 1712 (1974). With K.O. Watkms and J.C. Sullivan. (18) Oxidation of Free and Coordinated Thiols by Neptunium (VI), Inore. Chem., H,2360 (1974). With C.J. Weschler and J.C. Sullivan. (19) The trans-Effect in Octahedral Complexes: I. Rates of Ligation of trans-(Sulfinato-S)methanolbis(dimethylglyoximato) cobalt (III) Complexes .n Methanol, Inore. Chem., M,550 (1975). Wid J.C. Sullivan and K.O. Watkins. (20) The Reactivity Pattern Goveming Oxidation of Aquo Metal Ions by Neptunium (VII). Oxidation of Sil.ver(I) and Cobalt (l!)i9 Aqueous Perchloric Acid Media, botg. Chem., M,550 (1975). With J.C. Sullivan and K.O. Watkins. (21) Oxidation of Coordinated Thiol to Coordinated Disulphide yjia Induced Electron Transfer,
- 1. Chem. Soc. Chem. Commun., 749 (1975). With M. Woods and J.C. Sullivan.
(22) Reduction of an Organic Disulfide by a One-Equivalent Reagent. Kinetics and Mechanism of the. Reaction of Chromium (II) with p-Aminophenyl Disulfide in Aqueous Perchloric Acid, Incre. Chem., B,2799 (1975). With L.E. Asher. (23) Thiolato Sulfur as an Electron-Transfer Bridge. The Chromium (II)-Catalyzed Aquation of Thiolatobis(ethylenediamine) chromium (III) Complexes in Aqueous Perchloric Acid Media, Inorg. Chem.,11,139 (1976). With C.J. Weschler. (24) The Structum! Characterization, and Resulting Implications for the Mechanism of Fonnation, of Bis (2 mercaptoethylamine)ethylenediaminechromium(III) Perchlorate, [(en)Cr(SCH,CH 2NH 2):] CIO,, incre. Chem.,15,1183 (1976). With C. Stein, S. Bouma, J. Carlson, C. Comelius, J. Maeda, C.J. Weschler and K.O. Hodgson. 4
Page 16 Edward Deutsch (25) The Synthesis and Characterization of Cobalt (III) Complexes Containing a Coordinated Selenol. A Structural Trans Effect in N,Se-(2-Selenolatoethylamine) bis (ethylenediamine) cobalt (III) Nitrate, Incre. Chem., H, 1618 (1976). With C. Stein, P.E. Ellis and R.C. Elder. (26) The Effect of Added Ligands of the Rate of Chromium-Sulfur Bond Fission in Thiolatopentaaquochromium(III) Complexes. Evidence for a Sulfur-Induced Trans Effect in Chromium (III) Chemistry, Inqtg. Chem., M, 1631(1976). With L.E. Asher, (27) Kinetics and Mechanism of the Conversion of a Coordinated Thiol to a Coordinated Disulfide by the One-equivalent Oxidants Neptunium (VI) and Cobalt (III) in Aqueous Perchloric Acid, In2tg. Chem., M, 1678 (1976). With M. Woods, J. Karbwang and J.C. Sullivan. (28) Pulse Radiolysis Studies on the Reaction of Hydroxyl Radicals with Thiolatometal Complexes, incre. Chem., H,2864 (1976). With J.C. Sullivan, G.E. Adams, S. Gordon, W.A. Mulac, and K.H. Schmidt. (29) Kinetics of the Oxidation of Selenium (IV) by Neptunium (VII) in Aqueous Acidic Perchloric Media. Inore. Chem., H,2862 (1976). With J.N. Cooper, M. Woods and J.C. Sullivan. (30) Synthesis of a S-Bonded Sulfinic Acid Complex of Cobalt (III) by an Oxidative Route. A ' Structural Trans Effect in (2-Sulfinatoethylamine-N,S) bis (ethylenediamine) cobalt (III) Perchlorate Nitrate, Inqtg. Chem., H,2985 (1976). With B.A. Lange, K. Libson and R.C. Elder. (31) Synthesis of Radiopharmaceuticals by the Reduction of *TcOf: *Tc Labelled Hean Scanning Agents, Ann. Reoorts Inore. an.d Gen. Svnth. = 1975,311 (1976). With J.A. Siegel. (32) Structural Characterization of a Bridged 99-Tc-Sn-Dimethylglyoxime Complex. Implications for the Chemistry of 99m-Tc Radiopharmaceuticals Prepared by the Sn(II) Reduction of Pertechnetate, Proc. Nat. Acad..c S_ci.,13L 4287 (1976). With R.C. Elder, B.A. Lange, M.J. Vaal and D.G. Lay. (33) Organ Distribution of 99m-Tc-LakelleEl Aminethiols,In!. J. Nucl. Med. and Biosoev, d, 53 (1977). With M. Zalutsky, J.- Sullivan, A.M. Friedman and G.V.S. Rayudu. (34) Isotope Exchange Between ("Cry ] and Thiolatopentaaquechromium(III) Complexes. Correlation Between the Effectiveness of Thiolato Sulfur as an Electron Transfer Bridge and Sulfur-induced Trans Effects, Inore. Nucl. Chem. Letts., H, 92 (1977). With L.E. Asher. . (35) Trans Effect in Octahedral Complexes. II. Correlation of Dissociative Rates of Ligation of Selected trans-Bis (dimethylglyoximato) cobalt (IIII) Complexes in Methano;, inorg. Chem., M, 2273 (1977). With L. Seibles. (36) Thin Layer Spectroelectrochemical Study of Tetrakis(4-N-methylpyridyl) porphinecobalt(Ill),Inqtg. Chem., H,2650 (l977). With D.F. Rohrbach, W.R. Heineman and R.F. Pasternack. (37) Manganese. Technetium and Rhenium. Ann. Renorts incre, and Gen. Svnth. 1976,199 (1977). With K. Libson.
Page 17 Edward A. Deutsch (38) Thin Layer Spectroelectrochemical Studies of Cobalt and Coper Schiff Base Complexes in N,N Dimethylformamide. In " Characterization of Solutes in Non-aqueous Solvents", G. Mamantov, Ed., Plenum Press, p. 177,(1978). With W.R. Heineman and D.F. ;
. Rohrbach. ,
(39) Trans Effect in Octahedral Complexes. III. Comparison of Kinetic and Structural Trans Effects Induced by Coordinated Sulfur in Sulfito- and Sulfinatopentaamininecobalt(III) Complexes, In9Ig. Chem., H,431 (1978). With R.C. Elder, M.J. Heeg, M.D. Payne and M. Trkula. (40) Trichloroperchloratostannate(II), a Dianionic Tin (II) Complex Containing Bound Perchlorate: The Crystal Structure of[(NH )3 3 2 IngIg Chem., H,427 (1978). With R.C. Elder and M.J. ll]ee[g. 3CoS(0),C,H 3 (41) Kinetics and Mechanism of the Reduction of[(NH3 )3RuOH,], [(NH3 ),Ru] and [(en);Ru] by Uranium (!!I)in Aqueous Acidic Media. Correlations with the Predictions of the Marcus Theory, inoag. Chem., H, 2217 (1978). With C. Lavallee and D.K. Lavallee. (42) Synthesis and Characterization of Bis (ethylenediamine) cobalt (III) Complexes Containing Chelated Thioether Ligands. Crystal Structures of [(en)2Co(S(CH 3 )CH 2 CH 2 NH,]- [Fe(CN),) and [(en),Co(S(CH C 3 1296 (1978). With R.C. Elder, G.J. Kennard 2 a H )CH C00)] (SCN)2, luoIg. Chem., nd M.D. Payne. E, (43) Thioether Sulfur as an Electron Transfer Bridge. Kinetics and Mechanism of the Chromium (II) Reduction of(Alkyl 2-aminoethyl thioether-E,S) bis (ethylenediamine)- cobalt (III) Complexes, lagIg. Chem., H, 2225 (1978). With G.J. Kennard. (44) Production, Detection, and Characterization of Transient Hexavalent Technetium in Aqueous Alkaline Media by Pulse Radiolysis and Very Fast Scan Cyclic Voltammetry, J. Chem.jps. Chem. Commun., 1038 (1978). With W.R. Heineman, R. Hurst, J.C. Sullivan, W.A. Mulac and S. Gordon. (45) Synthesis, Characterization and Reactivity of Coordinated Sulfenic Acids. Incre. Chem., H,313 (1979). With I.K. Adzamli, K. Libson, J.D. Lydon and R.C. Elder. (46) Anunonium Hexachlorotechnetate(IV). Acta Crvst., B35,136 (1979). With R.C. Elder and 0.W. Estes. (47) Bis (ethylenedimine)(2 selenoacetato-OR) cobalt (III) Perchlorate, Acta Crvst., B35.164 (1979). With R.C. Elder and K. Burkett. (48) Ligating Ability of the Coordinated Thiolato Sulfur Atom. Interactions between Soft Metal Centers and the Thiolato-cobalt (III) Complexes [(en)2Co(SCH 2 CH 2 NH2 )] and [(en)2Co(SCH3 COO)]'. In2rg. Chem., H,2036 (1979). With M.J. Heeg and R.C. Elder.
- (49) Technetium Radiopharmaceutical Development. I. Synthesis Characterization, and-Structure of Dichloro[hydrotris(1-pyrazolyl)borato]oxotechnetium(V). J. Am. Chem Soc.,101,4581 (1979). With R.W. Thomas, G.W. Estes and R.C. Elder.
(50) Thin-Layer Spectroelectrochemical Studies of Cobalt and Co;3per Schiff Base Complexes. IngIg. Chem., H,2536 (1979). With D.F. Rohr aach and W.R. Heineman. (51) Inorganic Radiopharmaceuticals. In "Radiopharmaceuticals II", Proceedings of the 2nd Intemational Symposium on Radiopharmaceuticals, Society of Nuclear Medicine, New York, NY, p. 129 (1979).
nonu Edward A. Deutsch (52') Ligatirig Ability of the Coordinated Thiolato Sulfur Atom. 2. The Crystal Structure of ([(en) Co(SCH 3COO)),Ag}{ClO,),, a Model for an InneoSphere Electron Transfer Precur,sor c omplex. lacIg. Chem., B,554 (1980). With M.J. Heeg and R.C. Elder. (53) Oxidative Addition from a Six Coordinate to an Eight Coordinate Complex. Single-Crystal (1980). Stauctures of[Tc(diarsWith lavan, R. Whittle,K.A. d) Cl;]CIO, and R.C.and (Tc(diars) Cl,)PF . l. H2,2103 J.F. Johnson Elder. (54) Structural Characterization of a 99 Tc Diphosphonate Complex. Implications for the Chemistry of 99m Tc SkeletalInnging Agents, l. Am. Chem. Eng., H2,2476 (1980). With K. Libson and B.L. Barnett. (55) Synthesis and Characterization of the Aromatic Thiolato Complex (2 Merca 3toaniline-N S)his(ethylenediamine) cobalt (lli). Crystal Structure of [(en),Co(SC.H,N1: 3)]- (ClO )Cl. Inc.tg. Chent, H,945 (1980). With M.H. Dickman and R.J. Doedens. (50) Kinetics and Mechanism of the Reaction of Hydrocen Peroxide with Thiolato Complexes of Cobalt (Ill) and Chromium (lli). Cormaents on the Nucleophilicity of Coordinated Sulfur and the Stability of Coordinated Sulfenic Acids,Inttg. Chem.. H.1366 (1980). With 1.K. Adzarnli. (57) Separation of Technetium Hydroxyethylidene Diphosphonate Complexes by Anion. Exchange High Performance Liguid Chromatography. AnaJ. Che .t S,1106,(1980). With W.M. Heinemn and T.C. Pmkerton. , (58) O ptically Transparent Thin Layer Electrochemical Flow Cell for Liquid Chromatography. A.Dal. Gttm., S,1542 (1980). With T.C. Pinkerton, K. Hajizadeh and W.R. Heinernann (59) Characterization of(Thiooxalato-Q,E) bis (ethylenediamine) cobalt (lli) and Comparison to the Oxalate-Q,Q and Dithiooxalato S,S. Analogues. Single Crystal Structural Analysis of Co(SC(0) COO]3(S O ).2H2 0. In012. Chtm., H. 2083 (1980). With J.D. Lydon, [(en)kiulligan K.i and R.C. E;lder. (60) Trans Effect in Octahedral Complexes. 4. Kinetic Trans Effect Induced by the S-Bonded Thiosulfato Ligand in Bis (ethylenediamine) cobalt (lll) Complexes. In2Ig. Chem., H. 2265 (1980). With J.N. Cooper, J.D. McCoy and M.O. Katz. (61) Preparation and Biological Distribution of Technetium Diphosphonate Radiotracers Synthesized Without Stani.ous lon. J. Nwl. hild., H,859 (1980). With K. Libson, C.B. Becker, M.D. Francis, A.J. Tofe, D.L Fergusa and L.D. McCreary. (62) A Rational Synthesis of Coordinated Disulfides from Coordinated Thiols. Crystal Structure of[(en) (1980). With. D.L,Co(S(SC 2 2 Nosco and R.C. Elder.H )CH CH NH:)](ClO )3.H 0. In0Ig. Chem., H 2 (63) Technetium Rrf, pharmaceutical Development. 2. Preparation, Characterization, and Synthetic Utihn f the Oxotetrahalotechnetate(V) Species TcOX/. In9Ig. Chem.,19, 2840 (1980). With R.W. Thomas, A. Davison and H.S. Trop. (64) Protonation of tl Coordinated Thiolato Sulfur Atom. J. Ingig. Ngl. Chem.,12,1364 (1980). With 1.a. Adzamli and D.L. Nosco. (65) Coordination Stabilization of Reactive Molecales: Preparation of trans [(en)2Co(OH,)(S,0 )]*, A Cobalt (111) Complex Containing Disulphane Monosulphonate. [. Chem. Sc.c. Chem. Commun.,733 (1980). With J.P. Mittleman and J.N. Cooper. pr . - , ~ --y- -- - - - - . . ..,.,_y -
~
Page 19 Edward A. Deutsch . (66) Synthetic and Structural Aspects of Technetium Chemistry as Related to Nuclear Medicine. In " Inorganic Chemistry in Biology and Medicine" ACS Symposium Series No.140, Ed. A.E. Manell, American Chemical Society, Washington, D.C., p.103 (1980). With B.L. Barnett. (67) '[ tans.dichlorobis(g phenylenebis(dimethylarsine)) technetium (Ill), Perchlorate and Chloride Salts. Att_g .Cml., M, 1662 (1980). With R.C. Elder, R. Whittle, K.A. Glavan and J.F. Johnson. (68) Preparation and Characterization of[(en),Co(S O ))', a Cobalt (Ill) Complex Containing Chelated Q,S Thiosulfate. Inntg. Chem., JS,3d5d (1980). With J.N. Cooper, D.S. Buck and M.G. Katz. (69) Coordination Stabilization of Organic Intermediates. Crystal Structure of ((en),Co(SCH 11 NH )) 1.(NO ) '4H 0, a Stable Complex ofIodine(l). J. Am. . Chem. Sag., ,3784 (1980), d3ith b.L. Nosco, M.J. Heeg, M.D. Glick, R.C. Elder. (70) Heart Imaging with Cationic Complexes of Tecimetium. Science,2L4,85 (1981). With W. Bushong, K.A . Glavan, R.C. Elder, V.J. Sodd, K.L. Scholz, D.L. Fortman and S.J. Lukes. (71) Technetium Electrechemistry.1. Spectroelectrochemical Studies of Halogen, diars, and diphos Com,lexes of Technetium in Nonaqueous Media. IDntg. Chem., 20,3298 (1981). Witi R.W. Hurst and W.R. Heineman. , (72) Cationic Tc 99m Complexes as Pot:ntial Myocrdiallmaging Agents. J..Hugj. Mrd.,22, 897(1981). With K.A. Glami, V.J. Sodd, H. Nishiyama, D.L. Ferguson and S.J. Lukes. (73) Intramolecular Redox Decomposition of[(en) Co(SCH3 CH2 NH,)] and Related Complexes. In0Ig. Chem., 20,4017 (1981). Nith M.J. Root and 1.K. Adzamli. (74) Nucleophilkity of Coordinated Chalcogens as Evaluated in DMF-Water Media. In2IS. Chem.,20,4376 (1981). With M.J. Root. (75) Quantitative Determination of Pertechnetate by IFgh Performance Liquid Chromatography with UV Detection. J. Chromatoc. 222,249 (1982). With J.P. Zodda, W.R. Heineman and T.W. Gilbert. (76) Barium (2,6 Dimethylphenyl)carbamoylmethyliminodiacetate Trihydrate, BaHIDA. Agla Cml., M,733 (1982). With R. Faggiani, C.J.L. Lock, P. Richards and S.C. Srivastava. (77) (2 Aminoethanethiolato N,5) bis (1,2 ethanediamine) cobalt (III),(2 Mereaptoacetato. O S) bis (1,2 ethanediamine) cobalt (111), and Related Complexes. Inntg. Ss nth.,21,19 (190). With D.L.Nosco. (78) The Inorganic Chemistry of Tc 99m Myocardial Imaging Agents In " Applications of Nuclear and Radiochemistry", R. Lambrecht and N. Marcos, eds., Pergamon Press, New York (1982) p.139. With K.A. Glavan, W. Bushong and V.J. Sodd. (79) Crystal Strue.tures of Technetium Complcxes. Coord. Chem. Bsy.,44.,191 (1982). With G. Bandoli, U. Mazzi and E. Roncari. (80) Mechanistic Aspects of Transition Metal Lomplexes Containing Coordinated Sulphur. In
" Advances in Inorganic and Bioinorganic Mechanisms", Vol.1, A.G. Sykes, ed.,
Academic Press, London, p. 269 (1982). With M.J. Root and D.L. Nosco. +--y , . - - y
.lfdfe%
Edward A.Deutsch (81) T:chnetium Chemistry and Technetium Radio? h armaceuticals. Pics.. lacIg. Chem., M, 75 (1983). With K. Libson, S. Jurisson and L. P. Lindoy. (,82) In Vivo Distributions of Some Component Fractions of Tc(haBH,) HEDP Mixtums Separated by Ar, ion Exchange High Perfonnance Liquid Chromatographv. lat.16221 Radip.1.Isotooe H,907(1982). With T.C. Pinkert&., D.L. Femuson, W.R. Heineman, and K. Libson. (83) Preparation of"No Carrier Added" Technetium 99m Complexes: Determination of the Total Technetium Content of Mo 99fTc 99m Generator Eluents. In!.1. Ap.nl. 4diat. Isotooes, H,843 (1982). With W.R. Heineman, J.P. Zodda and C.C. Williams. (84) Synthesis and Characterization of Coordinated Disul6 des. Single-Crystal Structural Analysis of[(en)2Co(S(SC(CH 3)2COOH)C(CH 3)3 COO)](ClO,)2 2H2 0. IncIg. Chem., 21,3186 (1982). With J.D. Lydon and R.C. Elder. (85) Studies on the Chemistry and Reactivity of S Bonded Sulfenato Cobalt (Ill) Complexes. In0Ig Chem.,21,3180 (1982). With J.D. Lydon. (86) Basal Kinetic Studies of Tc 99m DMPE as a MyocardialIma ing Agent in the Dog.1
&s]. higd.,23,1093 (1982). With H. Nishiyama, R.J. Adol h, V.J. Sodd, K. Libson, E.L. Saenger, M.C. Gerson, M. Gable, S.J. Lukes, J. L. Vand theyden and D.L.
Fortman. (87) Effect of Coronary Blood Flow or. Uptake and Washout of Tc.99m DMPE and '" '201.1 Bs.l. his.d.,23,1102 (l982). With H. Nishiyama, R.J. Adol 3h, V.J. Sodd, K.1.ibson, M.C. Oerson, E.L. Saenger, S.J. Lukes, M. Gabel, J. L. Vanc erhr;yden and D.L. Fortman. (88) The Reactivity of C .nated Disul0 des.1. Nucleophilic Cleavage of the Sulfur-Sulfur Bond.1. Anar. Chan. bos., o M1, 844 (1983). With A. Ichimura and D.L. Nosco. (89) The Calcium Affinity of Coordinated Diphosphonate Ligands. Single Crystal Structure of [(en)2Co(0,P(OH)CH,P(OH)O di Shosphonate Skeletal Imaging,]CIO,.H,0. Agents. ID2Ig. Chem.,221331 (1983).Implications for the With S.S. Jurisson, Chem J.. . Benedict and R.C. Elder. (90) Synthesis, Characterization, and Electrochemical Properties of Tertiary Diphosphine Complexes of Technetium: Single Crystal Structure of the Protootype Cem alex II- [Tc(DPPE) r ]BF 3
, DPPE = 1,2 bis (diphenylphosphine) ethane. IngIg.C.1CD.,22, 1695 (1983 . With K. Lib on and B.L. Barnett.
(91) Studies on the Chemistry of Skeletal Imaging Agents. In " Technetium in Chemistry and Nuclear Medicine", E. Deutsch, M. Nicohm, and H.N. Wagner, Jr., eds, Cortina Int., Verona, Italy, p.45, (1983). With K. Libson. (92) Application of Technetium Chemistry to the Practice of Nuclear Medicine, in
" Technetium in Chemistry and Nuclear Medicine", E. Deutsch, M. Nicolini, and H.N.
Wagner, Jr., eds., Conina Int., Verona, Italy, p. 29 (1983). With K. Libson. (93) Determination of Penechnetate by Liquid Cluomatography with Reductive Electrochemical Detection. Anal. CigIo., H 708 (1983). With J.Y. Lewis, J.P. Zodda and W.R. Heineman.
' (94)- Synthesis and Characterization of Bis (ethylenediamine) cobalt (llI) Complexes ContainingChelated Thioether and Selenoether Ligands. Single Crystal Structure Analysis of[(en)3Co(S(CHCON(CH3 CH3)COCH3)CH C 2 22,2022 (1983). With L. Roecker, M.H. Dickman. NoscoD.b.11 and R.J. NH )](ClO,)3. In01E. ClM 3
Doedens
Edward A.Deutsch l (95) htyocardial Perfusion Imaging with 99m Tc DhiPE in hian. Em. J. N.us). hkd., f!. 371 (198.".). With hi.C. Gerson, H. Nishiyama, K.F. Libson, R.J. Adol ah. L. Grossman, V.J. Sodd, D.L. Fortman, J. L. Vanderheyden, C.C. Williamr and IL. Saenger. (96) Quencher Ligand Binding to Luminescent Complexes. Luminescent Phenothiazine Polypyridine Ru(II) Complexes. Chem. l'hn. Lnl., L01,353 0 (1983). With hi.J. Root, J.C. Sullivan and D.hfeisel. (97) bb(dimethylphosphino) ethane). Inl. J. gpj. Radiat. I]sotopes, 1611 (1983). With M, Preparation J. L. Vanderheyden, K. Libson, D.L. Nosco and A.R. Ketrmg. (98) Effect of pli on the Formation of Tc(NaBH,) h1DP Radiopharmaceutical Analogs.101 1
&d. Radigt. Isotones,14,1577 (1983). With S. Tanabe, J.P. Zodda nnd W.R.
Heineman. (99) The Biological Distributions of Some Technetium hiDP Components Isolated by Anion Exchan- 'igh Performance Liquid Chromatography. Int. 2. Md. Radiat.1setores, M, 1585 (1vn3). With S. Tanabe, J.P. Zodda, K. Libson and W.R. lieine. nan. (100) Synthesis and Characterization of a S Bonded Sulfenamide Cobalt ('ll) Complex. Single Crystal X Ray Structure of[(en),Co(S(NH2 )CH 2 CH 2 NH ](ClO,p'(C 2 2 0,)n H2 0. 3 3 Kinetics 3632 (1983).of the NH 050 Oxidation of[(en),Co(SCHWith . Nosco and J. Oliver.hl.S. Reynolds, J.M. Cassel, 2 2 (101) The Nucleop;tilicity of Thiolato Sulfur When Coordinated to Rutheium(II). Kinetics of the Alkylation of(8-mercaptoquinolinato) bis (2.2'bfpyridine) ruthenium (ll)by lodomethane. InnIg. Chem., H,622 (1984). With M.J. Root. (102) New Oxo Technetium (V) Complexes of N,N' Ethylenebis(acetylacetoneimine), N,N'- Ethylenebis(salicylidenetmine), and g Phenylenebis(salicylidencimine). X Ray Structures of the Complexes of N,N'-Ethylenebis(acetyla:etoneimine) and N,N'Ethylenebis(salicylidencimine) [D9Ig. Chnn., H,227 (1984). With S. Jurisson, L.F. Lindoy, K.P. Dancey, M. McParlin, P.A. Tasker and D.K. Uppal. (103) Bridging inorganic Chemistry and Nuclear Recent Advances Medicine. Comments in Tecimetium en Inorcanic Chemis Chemistry:try.,2,83 (1984). With K. Libson. (104) Technetium Electrochemistry. 2. Electrochemical and Spectroelectrochemical Studies of the Tertiary Diphosphine (D) Complexes tI-[Tc'"D,X 3 ]* (X = Cl.Br) and [Tc'D3 ]'. In2tg. Chem., H, 1272 (1984). With A. Ichimura, W.R. Heineman and J.-L. Vanderheyden. (105) Synthesis and Characterization of Cationic Technetium Complexes of 1,2-Bis (dimethylphosphino) ethane (DhiPE). Structure Determinations of it-[Tc"(DMPE),(OH)(O)]2',it-[Tc'"(DMPE),Cl,]* and [Tc'(DMPE)3]* Using X ray Diffraction, EXAFS and Tc-99 NMR. In0Ig. Chun., H,3184 (1984). With J.- L.Vanderheyden, A.R Ketring, K.Libson, M.J.Heeg, L. Roecker, P.Motz, R. Whittle and R.C. Elder. (106) Synthesis and Characterization of Technetium (V) Complexes with Tridentate Schiff Base Ligands X ray Crystal Structure of Chloro [N-(2 Hydroxyphenyl)- , salicylideneimmato]oxotechnetium(V). [nntg Chim, Acta,91,217 (1984). With G. llandoli, U. Mazzi, B.E. Wilcox and S. Jurisson. (107) Synthesis and Characterization of Technetium (V) 8-Quinolinolates. X-ray Crystal Structure of gis-Chlorobis(2-medni-8-quinolinolato)oxotechnetium(V). Inore. Chem., 11,2962 (1984). With B.E Wilcox and M.J. lleeg. l
Page 22 ; Edward A.Deutsch (108) An isothiocyanato Complex of Technetium (V). Spectroelectrochefcal and Single i Crystal X ray StructaralIn012. Bis (diphenylphosphino)cthane. Studies CKm.,on H, u-[Tc(DPPE)b(898 (1984).NCS),)', With G. Bandoli, U. Wh hiazzi , A. Ic imura, K.1.ibson and W.R.11eineman. (109) hiyocardial Scintigraphy with Technetium 99m Tris Dh1PE in blan. Bg. J. b'R4.1. hici., 2,403 (1984), With bl.C. Gerson, K.F. Libson, R.J. Adolph, A.R. Ketring, J. L. Vanderheyden, C.C. Williams and E.L. Saenger. , (110) Synthesis and Structure of gnas-[0,(TBP),Tc]'(TBP = 4 ku Butylpyridine) and Related Complexes. Inpag GKm.,12,4683 (1984). With hl.E. Kastner, P.ll. Fackler, and bl.J. Clarke. (111) 186 Re 11EDP: A Potential Therapeutic Bone Agent. Nuklearmedizin,H,81 (1984). With J. Weininger and A.R. Ketring. (112) Synthesis, Characterization and Electrochemical Properties of Technetium Complexes Containing Both Tetradentate Single Crystal Structure Schiff Base and hionodentate Tertiary) Phosphin of u-[N,N'ethylenebis(acetylacetonciminato bis (tripheny1 phosphine)) technetium (lli)licxafluorop,hosphate. lacIg. Chem., H, 4743 (1984). With S.S. Jurisson, K. Dancey, bl. hicPanlm and P.A. Tasker. Determination of Pertechnetate. Anal. G)im. As.ta .lfi2, , (113) Stripping 335 (1985).Chronocoulometry: With J.Y. Lewis, T.C. Pinkerton and W.R. licineman. 3 (114) Recent Developments in Technetium Chemistry as Applied to the Generation of New 99m Tc Radiophannaceuticals. In "1984 Yearbook on Radiopharmaceuticals", P.ll. Cox, ed., Gordon & Breach Publ., New York, p. 69 (1985). (115) Base ifydrolysis of Bis (ethylenediamine) cobalt (lli) Complexes Containing Chelated Thioether and Selenoether Ligands. Observation of Dramatic hiedium Effects. In012 OKm.,2116 (1985). With L.Roccker. (116) Synthesis of[Co(col " by lino Oxidation 3 of col (L = SCli C11 N113) 3 3 and Induced Electron r k),]ansfer. Crystal Structure of[Co(col,)3]2(SOj(Cl).. In . OKm., M,1118 (1985). With hi.J. liecg and E.L. Blinn. (117) Structural (EXAFS) and Solution Equilibrium Studies on the Oxotechnetiem(V) Complexes TcOXl and Tc0X (X = Cl,Br). Incig. Chem., M, 1472 (1985). With R.W. Thomas, hi.J. lieeg and R.C. I!! der. (118) Synthesis and Characterization of(Dipyridine)(terpyridine)(chalcogenoether) mthenium(ll) Complexes. Kinetics and hicchsnism of the Ilydrogen Peroxide Oxidation of[(bpy)(tpy)RuS(CH 3),] to [(bpyT(tpy)RuS(0)(CH )3}. Kinetics of the Aquation 3 of [(bpy)(tpy)RuS(0)(Cil )2} 3
*. IDQIg. CKm., M, 1464 (1985). With hl.J. Root.
(119) Comparison of the Chemical and Biological Propedies of g-[Te(DhiPE),Cl,]* and g- [Re(Dh1PE);Cl )', where Dh1PE = 1,2 bis (dimethylphosphino) ethane. Single-Crystal Structural Anal;ysis of g-[Re(DhiPE )2Cl,)PF IncIg. Chem., M, 1666(1985). With J.L.Vanderheyden and hi.J. IIeeg. (120) Reactivity of Coordinatel Disulfides. 2. Competitive S S and Co S Bond Cleavage in the Base liydrolysis of the ku Butyl Disuinde Cobalt (lll) Complex [(en)2Co(S(SC(Clii)3) Cl13 Cl1 NI13 )]". Incia. Orm., M, 1674 (1985). With A. Ichimura and D.L. Nosco.
Page 23 . . Edward A. Deutsch , (121) Technetium Flectrochemistiy. 3. Spectroelectrochemical Studies on the Mixed Ligand
.L]' where L is a Tetradentate Schiff Base Technetium Ligand and PR R'is(lli) Complexes a Monodei. tate Teniary ums-[Tc(PR,R') Phosphine Ligand. lactg. C (1985). With A. Ichimura and W.R. Heineman.
(132) Thioether, ~Biolato and 1,1 Dithio; Complexes of Bis (2,2' bipyridine)M(H)(M = Ru, Os), lantg. Chem.,2.4,2731 (198 i M.J. Root, B.P. Sulhvan and T.J. h' yer. (123) Structure of sjs Bis (acetonitrile) bis (oipyridine) ruthenium (II)Hexafluorophosphate. [Ru(C H3 N) w R. tho:ener. (C H,N,);)(PF,),. Mta .Cml., CH,684 (l985). With M.J. Eceg and (124) Chelate and Steric Effects in he Aquation of the Thio!ato-Chromium (Ill) Complexes [(en) Lt(S X COO))* Where X = CH2 , CH,CH* and C(CH Anchimeric Assis,tance in Competitive Cr S, Cr N and C O Bond Fission. b), :g. Chem., M,4 (1985). With I.K. Adzamli. (125) Cationic Radiotracers as Myocardial Radiopharmaceuticals. In Vol I "Ra Npharmaceuticals: Progress and Clinical Pers ectives", A.R. Fritzberg, ed., CRC Preu, Boca Raton, FL., p.1 (1986). With D.M. ieland . (126) Studies on Commercially Available 99 Mo/99m Tc Radionuclide Generators. I. Comparison of Five Analytical Procedures foi Determination of Total Technetium in Generator Eluants Annl. Radiat. lag.t., H,165 (1986). With M.E. Holland, W.R. , Heineman and E.M. Holland. (127) Studies on Commercially Aval:able 99 Mo/99m Tc Radionuclide Generators. II. Operating Characteristics and Behav:or of 99 Mo/99m Tc Generators enl. Radiat. Jml., E,173 (1986). With M.E. Holland and W.R. Heineman. (128) HPLC Separated Fractions of 99m Tc(NaBH,)-HEDP as MyocardialInfaret Imaging Agents. Annl. Radiat. Itet., H,341 (1986). With D.L. Ferguson, K. Libson, J.P. Zodda and W.R. Heineman. (129) The Effect of Formulation Conditions on the Distribution of 99m-Tc(NaBH,)HEDP Components Separated by Anion Exchange HPLC. Accl. Radiat.110.1., H,345 (1986). With J.P. Zodda S. Tanabe and W.R. Heineman. (130) Evaluation in Dogs and Humans of Three Potential Tc 99m Myocardial Perfusion Agents. ,[. hLusl. hied., H,409 (1986). With P. Gerundini, A. Savi, M.C. Gilardi, A. Margonato, G.Vicedomini, L. Zecca, W. Hirth, K. Libson, J.C. Bhatia and F. Fazio. (131) The Chemistry of Rhenium and Technetium as Related to the Use ofisotopes of These Elements in Therapeutic and Diagnostic Nuclear Medicine. Nuc. Med. I)i91., H,465 (1986). With K. Libson, J. L. Vanderheycen, A.R. Ketring and H.R. Maxon. (132) . Electron Transfer Reactions of Technetium Complexes.1. Rate ot'the Self Exchange Reaction of the Tc(I)/Tc(II) Couple [Tc(DMPE)3]' Where DMPE = 1,2-bis (dimethylphosphino) ethane, inctg. Chem., H,3367 (1986). With htN. Doyle, K. Libson, M. Woods and J.C.Sullivan. (133) The Chemistry of Technetium Di hosphonate Bone laiaging Agents. Medicin_a Nuclear Informacao,2,35 (1986). With if. Libson and W.R. Heineman. (134) 99m Technetium Myocardial Perfusion Imaging Agents. Medicina Nuclear informacao.
-2,41 (1986). With K. Libson and J L.Vanderheyden.
- - - - . , , -- w.,--, -
m , , . , , , - - , - , . - , , - - - - , , - , - . - , - . . - . , - - - -
N A. Deutsch 0 35) Technetium 99m MyocardialImaging Agents. In"' Technetium in Chemistry and Nuclear Medicine,2", M. Nicolini, G. Bandoli and U. Mazzi, eds., Raven Press, New York, p.161 (1986). With K. Libson and J. L. Vanderheyden.
-(136) Electrochemistry of Technetium Radiophannaceuticals: Coulometric Redu-tion of Pertechnetate in the Presence of HEDP. In " Technetium in Chemistry and Nuclear Medicine,2", M. Nicolini, G. Bandoli and U. Mazzi, eds., Raven Press, New York, p.97 (1986). With W. R. Heinemt.n and R. B. Scott.
(137) Technetium 99m Radiopharmaceuticals for Brain Perfusjon Imaging. In " Technetium in Chemistry and Nuclear Medicine,2", M. Nicolini, G. Bandoli and U. Mazzi, eds., Raven Press, New York, p. 123 (1986). With M. Neves and K. Libson. (138) Evaluation ofNew 99m Tc Radiopharinaceuticals for Heart and Brain Studies. In
" Technetium in Chemistry and Nuclear Medicine,2", M. Nicolini, G. Bandoli and U.
Mazzi, eds., Raven Press, New York, p.333 (1986). With P. Gerundini, A. Savi, D.A. Tyrrel and F. Fazio. (139) Tc(V) Cornplexes with Schiff Base Derivatives of Glucosamine. In ' Technetium in Chemistry and Nuclear Medicine,2", M. Nicolini, G. Bandoli and U. Mazzi, eds., Raven Press, New York, p.131 (1986). With A. Duatti, A. Marchi, L. Magon and J. L. Vanderheyden. (140) Recent A aplications of Electroanalysis in the Basic Medical Sciences. In *
"Electroc 1emistry, Sensors and Analysis", Elsevier Science Pub., Amsterdam, p.345 (1986). With W.R. Heineman and H.B. Halsal.
(141) Characteri: ation of Technetium Radiopharmaceuticals by Thin-Layer Spectroelectro-chemistry. J. Pharmaceut. Biomed. Anal.,4,777 (1986). With J.R. Kirchhoff and W.R. Heineman. (142) Thin Layer Spectroelectrochemistry ofInorganic and B;ological Systems, in "Analytiktreffen 1985: Elektrochemische Analysenmethoden", Wessenschaftliche Beitrage Der Karl Marx Universitat, Leipzig, p. 132 (1986). With W. R. Heineman and J. R. Kirchhoff. (143) Synthesis and Structure of an Amino Sugar Schiff Base Complex of Technetium (V) Containing Salicylaldehyde in an Unusual Coordination Mode. In9.rg. Chem., M,2182 (1987). With A. Duatti, A. Marchi, L. Magon, V. Bertolasi and G. Gilli. (144) Technetium Electrochemistry. 4. Electrochemical and Spectroelectrochemical Studies on the Bis (tertiary phosphine or arsine) (D) rhenium (lll) Complexes, trans-[ red,X ]* (X = Cl,Br). Comparison with the Technetium Analogs. Ingrg. Chem., M,3108 (1987). With J.R. Kirchhoff and W.R. Heineman. (145) Neutral 99m-Technetium (II) Complexes as Potential Brain Perfusion Imaging Agents. Nud. hid. Hi.9J.. .L4, 503 (1987). With M. Neves and K. Libson. (146) The in Vivo Inorganic Chemistry of Technetium Cations. J. EnrJ. hhd., M, 1491 (1987). With W. Hirth. , (147) Development of Nonreducible 99m Technetium (lli) Cations as Myocardial Perfusion Imaging Agents, initial Experience in Humans, l. Nucj. hkd., M, !870 (1987). With J.-L Vanderheyden, P. Gerundini, K. Libson, W. Ilirth, F. Colombo, A. Savi, L. Zecca and F. Fazio. u -, - . , m,, - , -- - . N r- - e e- e % ,.. r .--,
IFase W . Edward A. Deutsch (148) Technetium Electrochemistry,5. Spectroelectrochemical Studies on the Hexachlorotechnetate(IV) an 11exabromotechnetate(lV) Complexes in Aqueous Sledia. Insg. Chem.,25,3718 (1987). With E.W lluber and W.R. lieineman. (149) Re 186(Sn)IIEDP for Treatment of hiultiple hietastatic Foci in Bone: Human Biodistribution and Dosimetric Studies. Radioloev. Ms,501 (1988). With H.R. htaxon, S.R. Romas, K. Libson, S.J. Lukes, C.C. Williams and S. Ali. (150) A Technetium (V) Complex Resulting from intramolecular Ring Closure of a Tridentate Schiff Base Ligand. X ray Crystal Structure of Chlorobis(2-(2 hydroxyphenyl) benzothiazolato) oxotechnetium(V). Insg.Chim. As.ta,1M 55 (1988). With B. E. Wilcox, J. N. Cooper and R. C. Elder. (151) Synthesis and Characterization of Some Polypyridine Ruthenium (!!) Complexes Containing S Bonded Thioether Ligands. A ray Crystal Structures of cis and trans-Bis (2,2' Bipyidine) bis (Phenothiazine S)mthenium(!!) Hexafluorophosphates. Insg. . Chem., H, 558 (1988). With R. Kroener and hi.J. Heeg. (152) Electron Transfer Reactions of Technetium and Rhenium Complexes. 2. Relative Self-Exchange Rate of the hi(1)/hi(II) Couples [hi(DhiPE)3] Where hi = Tc or Re and DhfPE = 1,2 Bis (dimethylphosphino)cthane. Insg. Chem.. E,999 (1988). With K. Libson, bl. Woods, J.C. Sullivan, J. W. Watkins and R.C. Elder. (153) Technetium Electrochemistry. 6. Electrochemical Behavior of Cationic Rhenium and T Technetium Complexes in Aqueous and Aqueous hiicellar Solution. Insg. Chem., H, ' 3608 (1988). With J. R. Kirchhoff and W. R. IIcineman. ll) Redox Couple. X-ray Crystal (154) DPPEStructural and] and Structures ofimni-[Tc"(DPPE)3Cl 3 Kinetic Inni:[Tc
= 1,2 bis (diphenylphosphino)cthane, Investigations lung Chem.,
Cl 3 3 2,3614 (1988). With of a Tc(Il K.Libson, bl.N.Doyle, R. W. Thomas, T. Nelesnik, hi. Woods, J. C. Sullivan and R. C. Elder. (155) Thiolato-Technetium Complexes. I. Synthesis and Characterization of Bis (tertiary-diphosphine) Technetium (lli) Complexes Containing hiethane-thiolato Ligands. Single Cry"stal Structural Analyses oflans-[Tc"(SCH )3(DMPE)2]CF 3 3 S0 3and 1203- [Tc (SCli)3(DEPE) 3 PF where DhfPE = 1,2 Bis (dimethylphosphino)cthane and DEPE = 1,2 Bis (dictb]ylph,osphino) ethane. Insg. Chem., H,4113 (198 Konno and M.J. Heeg. (156) Electrochemistry of 0xo-Technetium (V) Complexes Containing Schiff Base and 8 Quinolinol Ligands. lang. Chem., H,4121(1988). With F. Refosco, U. Mazzi, J. R. Kirchhoff, W. R. Heineman and R. Seeber. (157) Reactivity of 2-(2 Hydroxyphenyl)benzothiazoline with the Oxotetrabalometal(V) ate Complexes [h10X,]'(M = Tc, Re; X = Cl, Br). Synthesis and Characterization of new Oxo M(V) Complexes Containing 2-(2-Hydroxyphenyl)benzothiazole. Crystal Structure of Tetraphenyl arsonium Oxotrichloro[2-(7. hydroxyphenyl)berizothiazolato]- technetium (V) ate. Insg. Chem., H,4203 (1988). With A. Duatti, A. Marchi, R. Rossi, L. Magon, V. Bertolasi and F. P:llucci. (158) Quantitative HPLC Determination of 99m Pertechnetate in Radiopharmaceuticals and Biological Samples. I. Technique Development, b'ugj. Med. Biol., M,493 (1988). With T Zhou. W. Hirth and W. R. Heineman. (159) Radionuclide Pallitation of Cancer Related Bone Pain. Southeastern Chanter. Sac. Nucl. hied., XVll 1 (1988). With H. R. hlaxon, !!!, L. E. Schroder, S.R. Thomes, K. F. 1 Libson, J. S. Moulton, C. C. Williams and V. S. Hertzberg.
, n-. -~ ' -
r,---
^ " . Page 26 '
Edward A. Deatsch
~
, (160) New Tc 9k Labelled Complexes for Myocardial Imaging. Toshiba Medical Review. No. 24,30 (1988). With P. Gerundini, R. Benti, O.1 ragasso, A. Savi, P. Zoll, F. Colombo and F. Fazio.
'(161) . A Convenient Synthetic Route to the Monocondensation Products of Pentane 2,4 dione and Aliphatic, a.wDiamines. Synthesis, X ray Structure and Magnetic Propertics of a 3-octene 2-one, lp.nfg.
Trinuclear Copper Gim. MLa., Lf_Q,65 (ll) Complex (1988). with 8 Amino With M. Kwiatkowski, 5 aza-4 methy]kowski, A. Olechnowicz E. Kwiat and D. M.110. (162) Tc 99m Agents for Myocardial Perfusion Studies. In "New Procedures in Nuclear Medicine", R. Spencer, ed., CRC Press, Boca Raton, FL, p. 81 (1988). With P. Gerundini and F. F izio. (163) Pulse Radiolvsis Studies on Pertechnetate and Perrhenate in Aqueous Media. Decay of the Technetium (VI) Transient. InEg. &m.,3,375 (1989). With K. Libson, J. C. Sullivan, W. A. Mulac and S. Gordon. (164) The Noah's Ark Experiment: Species De 3endent Biodistributions of Cationic 99m Tc Com alexes. Mud. Med.11191., M,191 (: 989). With A.R. Ketring, K. Libson, J. L. Vand erheyden and W.J. Hirth. (165) Anion exchange liigh Performance Liquid Chrome:ography of Technetium Labeled Phosphononcetic Acid SkeletalImagin g A gent Preparations. J. Chromatocrnehv. Biomed. Arml.,488,463 (1989). With M. A. Aide nasser and W. R.11eineman. - (166) Chromatographic Characterization of Electrochemically Ger. crated Technetium HEDP SkeletalM,285 Talanta. Imaging (1989).Agents (where liEDP = 1,1 hydroxyethylidine meman. di 3hospWith R. B. Scott (167) Synthesis, Structure, and Magnetic Properties of a New Chloro Bridged Dimeric Copper Complex, Bis (p chloro) bis (8 amino 5 aza 4 methyl 3 octene 2-onato)dicopper(II). Insg. Gim. Mla,118,37 (1989). With E. Kwiatkowski, M. Kwiatkowski, A. Olechnowicz, J. Mrozinski and D. M. Ilo. (168) Thiolato-Technetium Complexes. 2. Synthesis, Characterization, Electrochemistry and Spectroclectrochemistry of the Technetium (Ill) Complexes kans-[Tc(SR)2(DMPE)g, where R is an Alkyl or Benzyl Grou 3 and DMPE is 1,2 Bis (dimethylphosphino) ethane, incIg. @m., H, 1174 (1989). Wit i T. Konno, J. R. Kirchhoff a~d W. R. Heineman. (169) Technetium 99m Complexes of Dimethylaminomethylene Di shosphonate (DMAD).1. Anion Exchange HPLC Characterization of 99m Tc(NaBH,)aMAD Mixtures. Mic.l. . hM.11191., M,301 (1989). With M. E. Holland and W. R. Heineman. (170) Technetium 99m' Complexes of Dimethylaminomethylene Dipohsphonate (DMAD). II. Biological Distributions of 99m Tc DMAD Components isolated by Anion. Exchange HPLC. Nud. hM.11101., M,313 (1989). With M. E. Holland, J. Bugaj and W. R. IIcineman. (171) Synthesis'and Characterization of Tecluietium(Ill) Cumplexes Containing 2,2'Bip) ridine and 1,10-Phenanthroline. X Ray Crystal Structures of sis (Cl).imns(P)- [TcCl 3(P(CH 3)#C.H 3 (phenanthroline)]B(d),(H ),, and ris(Cl).kans(P)-[TcCl (P(Cil,CH )(C,li ) )2bipyrid 3 3 2 3 2 3 3 5 (bipyridine)]SO,CF3 . Ingig. Chem., L8,1743 (1989). With B. E. Wilcox and D. M. Ho.
Edward A. Deutsch . (172) Thiolato Technetium Com Georr.ctrical Isomersand (Cig plexes.
]iam 3. Synthesis and bis Bis (p-chlorobenzenethiolato) X ray (1,2 Structural bis Studies on th t
(dimethylphosphino) ethane) technetium (ll). Intg. Chem., H, 1694 (1989). With T. . Konno and M. J. Heeg. . O 73) Factors Influencing Electroanalytical Measurements in Aqueous Surfactant Media. Anal. 1 41.,22,1323 (1989). With J. R. Kirchhoff and W. R. Hememan. (174) Technetium Diphos abonate Skeletal Imaging Agents: EXAFS Structural Studies in Aqueous Solution. ;mtg. Chem., H,2899 (1989). With J. L. Martin, J. Yuan, C. E. a.unte, R. C. Elder, and W. R. Heineman. (175) Synthesis and Characterization of Mixed Ligand Technetium (II) Complexes Containing iIalides, Phosphines and Either 2.2' Bipvridme,1,10 Phenantroline or 2,2':6',2"- Terpyidine. X Ray Crystal Structures olsis(Cl),1 tam (P).[TcCL(P(CH3 )2C.H3 ) (phenanthroline)) and Itam(P)-{TcBr(P(CH )2C H,),(terpyridin'e)]. Intg. Che,m., 3 3 ,3917(1989). With B. E. Wilcox and D. M. Ho. (176) Biodistribution of Tc 99m Metho Isobutyl Isonitrile (MIDI)in Humans. Eut. l. Nnsl. hird., U,597 (1989). With A. Savi, P. Gerundini, P. Zoli, L. Maffioli, A. Compierchio, F Colombo and M. Matarrese. (177) Synthesis, Structure and Magnetic Properties of a New Chloro bridged Dimeric Copper Ccmplex, Bis (p chloro) bis (8 amino 5 aza-4 methyl 3 octene 2-onato)-dicopper(II). , IMIS. Chim. AEla.,13,37 (1989). With E. Kwiatkowski, M. Kwiatkowski, A. Olechnowicz, J. Mrozinski and D.M. Ho. (178) Intramolecular Quadridentate Synthesis: X ray Crystallogr hic Analysis of [(NH2CH CH,NH Co(NH (CH 2): Chsm.,:d,339 (th)89). i W;th L. Roccher, J.D. Lydon, 3 3 illis and A.M. 3 A.C.N=C(NH 3 Sargeson. )CH S(CH (179) Tc 99m Complexes of a,a Disubstituted, a Hydroxy Carboxylic Acids. Arnl. Radiol.. hn!.,it,221 (1990). With F. Colombo, M. Matarrese and F. Fazio. (180) Mono and Di nuclear Nickel (II) Complexes with Schiff Base:: derived from 4-Substituted 2,6 Diformylphenol and 7-Amino-4 methyl 5-azabept-3-en 2 one; Crystal and Molecular Structure of[4 Chloro 2,6 bis (4 methyl-2-oxo-5,8-diazanona 3,8-dienyl)phenolato(3-)) dinickel(II) Bromide Hemihydrate.1. Chem. Sp_c. Dalton Trans., 3063 (1990). With M. Kwiatkowski, E. Kwiatkowski, A. Olechnowicz and D.M. Ho. (181) 186 Re(Sn).HEDP for the Treatment of Painfn! Osseous Metastases: Initial Clinical Experience in 20 Patients with Hormone-Resistant Prostate Cancer. Radiolocv, .[26 155 (1990). With H. R. Maxon, L. E. Schroder, S. R. Thomas, V. S. Hertzberg, H.I. Scher, R. C. Samaratunga, K. F. Libson, C. C. Williams, J. S. Moulton and H.J. Schneider. U 82) The Inorganic Chemistry of Technetium and Rhenium as Relevant to Nuclear Medicine. In " Technetium in Chemistry and Nuclear Medicine 3", Raven Press, NY, p 13,(1990). With K. Libson, and J.-L. Vanderheyden. .(183) Develop [nent of New 99m Tc Myocardial Perfusion Imaging Agents. In " Technetium in Chemistry and Nuclear Medicine 3", Raven Press, NY, p. 365 (1990). With K. Libson, C. Messa, M. Kwiatxowski, F. Zito, T. Kelso, F. Colombo, M. Matarrese, X. Wang. G. Fragasso and F. Fazio. (184) Synthesis and Characterization of Novel 99-Technetium (Ill) Phosphine Complexes, llPLC Characterization and Rat Biodistribution of the Tc 99m Analogs. In " Technetium in Chemistry and Nuclear Medicine 3", Raven Press, NY, p. 221 (1990). With F. Refosco, G. Bandoli, A. Duatti, U. Mazzi, A. Moreseso. M. Nicolini and F. Tisato.
.m .w-s. . , _ . , . , . . . , ,.m . - . .
' M A. Deutsch (l'85) Comgarative Chemical and Biological Properties of ti e RCBF Agents ""'Tc d,1 CB PAO and Tc d,1 HM PAO In " Technetium in Chemistry and Nuclear Medicine 3", Raven Press, NY, p. 469 (1990). With F. Colombo, K. Libson, Z. Jiang, G. Deleide, M.
Matarrese, C. Bonino, J. Belletire, F. Lunghi and F. Fazio. (186) ' Kinetics and Mechanism of Ligand Substitution on Analogous Technetium (V) and Rhenium (V) Com )lexes. In " Technetium in Chemistry and Nuclear Medicme 3", Ra ven Press, NY, ?. 31 (' 990). With K. Libson, L. Helm, A. Roodt, C. Cutler, A.E. Merbach and J.C. Su livan. (187) Preliminary Comparison of the RCBF Tracers ""'Tc d.1 HM PAO and "Tc d,1 CB-PAO in Human Volunteers, in " Technetium in Chemistry and Nuclear Medicine 3", Raven Press, NY, p. 699 (1990). With C. Messa, F. Zito, F. Colombo, C. Rossetti, G. Taddei, O. Lucignani and F. Fazio. (!88) 186 Re(Sn) HEDP for the Treatment of Painful Osseous Metastam Initial Clin. cal Experience, in " Technetium in Chemistry and Nuclear Medicine 3", Raven Press, NY, p. 733 (1990). With H.R. Maxon, L.E. Schroder, S.R. Thomas, V.S. Hertzberg, R.C. Samaratunga, K. Libson, C.C. Williams, J.S. Moulton and H.J. Schneider. (189) New Nickel (II) and Paladium(ll) Complexes with Unsymmetrical Quadridentate Schiff Bases Derived from 8 amino 4 methyl 5 azaoct 3-en 2-one. Crystal and Molecular Structure of(4,10 Dimethyl-3-(nitroso-kappa 2N)-5,9-(diaza kappa 2N) trideca-3,10, diene 2 12-(dinoato kapa 0) niclcle 11. J. Chem. S.gs. Dalton Imm.,2497 (1990). , (190) Radiopharmaceuticals. In "1991 Yearbook of Science and Technology". McGraw Hill Publ. Co., New York, NY, p. 353 (1991). (191) Technetium Electrochemistry. 7. Electrochemical and Spectroelectrochemical Studies on Technetium (111) and -(11) Comp' exes Containing Polypyridyl Ligands. IDEg. Chem., E,688 (1991). With B.E. Wilcox. (192) X ray Structural and NMR Characterization of the Copper (I) Dimer [Cu(dmpe),],(BF,)2, Where Dmpe is 1,2 Bis (dimethylphosphino)cthane. lag.tg. Chem., M,4541 (1991). With B. Mohr, E.E. Brooks and N. Rath. (193) Electron Transfer Reactions of Technetium and Rhenium Complexes. 3. Pulse Radiolysis Studies on Irans-(M*X,(DMPE)2)* and [M'(DMPE)3)* Complexes in Aqueous and Aqueous Surfactant Media, Where M = Tc or Re, X = Cl or Br, and DMPE = 1,2-Bis (dimethylphos 3hino) ethane. Ingr.g. Chem., E,4545 (1991). With A. Roodt, J.C. Sullivan and D. N eisel. (194) Synthesis and Characterization of the (Thiolato) rhenium (Illi Complexes 1. tans- [Re(SC,1 :(Et 2PCH C 3 3 H pet ),Ph.,H pet )3]PF.,itans-[Re(SC H.-n-Cll )3 h );]CF SO 1/ 3 (Et 3PCH 3 3 3 and Imns-[Re(SC.H 3
),(PhhCH 2 CH 3 PP 2 3 3 NCCH.3 . Chr2n., M,4920 (1991). With L.S. Chang, S-l. Aizawa and M.J. Heeg.
(195) Rhenium 186 Hydroxyethylidene Diphosphonate for the Treatment of Painful Osseous Metastases. Se_ min. Nus.l. hirt,22,33 (1992). With H.R. Maxon, S.R. Thomas, V.S. Hertzberg, L.E. Schroder, E.E. Englaro, R. Samaratunga, H.l. Scher, J.S. Moulton, K.F, Deutsch, H.J. Schneider, C.C. Williams and O.J. Ehrhardt. (196) Multinuclear NMR Studies of Ligand Exchrige Reactions on Analogous Technetium (V) and Rhenium (V) Complexes. Relevance to Nuclear Medicine. Ihly. Chim. Asia.,21, 210 (1992). With L. Helm, K. Deutsch and A.E. Merbach. _m_. . _ _ _ . _ . . _ _ _ . _ _ . - . . - . _ .
rage 2T Edward A. Deutsch (197) A New, General Syntheuc Route to Multidentate N,5 Ligands for Use in 99m- . Technetium Radiopharmaceuticals. Pre 3aration of Diamidodisulfur (DADS), Diamidodith.ol(DADT) and Tripodale 33 S Prototypes. Comparative Biodistribution of S("ystems. J. Me_.d Chem., With H,274 (1992).*TcO D. Stepr.iak BiniakiewiczDADS] Analogs Which and B. Chen. (198) niolato Technetium Complexes. 5. Synthesis, Characterization and Electrocheraical Properties of Bis (o phenylenebis(dimetfiylarsine)) technetium (H) and technetium (Ill) Complexes with Diolato Ligands. Single Cystal Structual Analyses of trans- [Tc(SCH ), DIARS)JPF, and IInar[Tc(SC,H )2(DIARS) '. IngIg. Chem., H,1173 (1992). Wi(th T. Kon o, M.J. Heeg, J.A. Stuckey, 3 3 r J.R. Ki,]chhoff and W.R. He (199) niolato Technetiurr im Properties and the Sing, 'plexes. 6. Synthesis, Characterization. Electrochem
= 3.4 toluenedithiolate and DalPE = 1,2 Bis (dimethylphosphino) ethane. J. Chem. Ecs.
D31120 IrArn.,3069 (1992). With T. Konno, J.R. Kirchhoff, M.J. Heeg, and W.R. Heineman. (200) Kinetic and Structural Studies on the Ox6tetracyanotechnetate(V) Core. Protonation and Ligation of Dioxotetracyanotechnetate(V). Cystal Structure o'2,2' Bipyridinium Iran-Oxothiocyanatotetracyanotechnetate(V). In2tg. Gnn., H, woo (1992). With A. Roodt, J.G. Leipold and J.C. Sullivan. (201) 99m Tc Radiopharmaceuticals For Brain Perfusion Imaging. In " Proceedings of The , Brain Perfusion Imaging Workshop", US DOE, OER, Washington, D.C., p. 8 (1992). With W. Volkert. (202) Synthesis and Renal Excretion of Technetium 99m Labeled Organic Cations. J. Mud.. Med., H. 2190 (1992). With K.M. Herzog, K. Deutsch, E. Silberstein, R. Sarangarajan and W. Cacini. (203) Rhenium 186 Hydroxyethylidene Diphosphonate for the Treatment of Painful Osseous Metastases. Np_d. Geneeskd. Hul]., M,63 (1992). With H.R. Maxon, S.R. Thomas, V.S. Hertzberg, L.E. Schroder, E.E. Englaro, R. Samar stunga 11.1. Scher, J.S. Moulton, K.F. Deutsch, H.J. Schneider, C.C. Williams and G.J. Ehrhardt. (204) Preparation, Characterization, and "O NMR Kinetic Studies of Analogous Technetium (V) and Rhenium (V) Complexes Which Contain a Seven Membered Chelate Ring. Single- Crystal Structure Analyses of[Ph,P] [TcO(DBDS)] and [Ph,As]- (ReO(DBDS)], Where DBDS N,N' Bis (mercaptoacetyl) butane 1,4-diamine. jngIg. . Chem., H,4683 (1992). With B. Chen and h1.J. Heeg. (205) Bone Seeking Radiopharmaceuticals in Cancer Therapy. In " Advances in Metals in Medicine", (1993) With W. Volkert (207) Solid State 31 P NMR and Structural Studies on Cu(I) Phosphine Complexes of Tetradentate-N F.F. Brooks, M.J. 2 P Heeg and D.M. Ho. Ligands. lunts. Gun.,32,3236 (1993). Wi (208) Potential Gallium-68 Tracers for Imaging the Heart with Positron Emission Tomography: Evaluation of Fo'ir Gallium Complexes with Functionalized Tripodal Tris (salicilaldimine) Ligands. J. Nud. Med., M,228 (1993). With M. A. Green C. J. Mathias, W. L. Neumann, P. E. Fanwick and M. Jan k. (209) Preparation, Characterization, Electrochemical Proper:ies and Single Crystal Structural Analysis of[Te(SCP),(DMPE)2](PF )3, where SCP is the Zwitterionic Ligand
)
-SCH 2 P'(CH ),(Cll,),P(S)(CH,ith 3
Polyhedroa,12,749 (1993). W , and DMPE K-1. Okamoto, J. R. Kirchhoff, W.ethane is 1,2 Bis (dimethylphosphino) R. H M. J. Heeg. .
~ Edward A. Deutsch -
(225) Comparison of Tc 99m Q3 and TI 201 for Dectection of Coronary Anery Disease in llumans. J. Mut!. hied., H,580 (1994). With M. C. Gerson. J. Lukes, D. Biniakiewicz, L. C. Washburn, A.li. Elgazzar, R. C. Elder and R. A. Walsh.
'(226) ,lieptacoordinate Rhenium (lli) bis (terpyridine) Complexes: Synthesis Characterizations and Crystal Structures of[Re(terpyridine),X) (X = GH, Cl, NCS). Substitution Kinetics of[Re(terpyridine),OH) *. Inqtg. Chem., H,3442 3451 (1994). With R.
Rall, F. Weingart, D.M.110, M.J. Heeg, and R. Tisato. (227) Human Biodistribution, Dosimetry and Clinical Use of Technetium (IU) 99m-Ql2. J., Mutl. Mrd., H,1571 1580 (1994). With C. Rossetti, G. Vanoli, G. Paganelli, M. Kwiatkowski, F. Zito, F. Colombo, C. Bonino, A. Carpinelli, R. Casati, K. Deutsch, M. Marmion, S.R. Woulfe, F. Lunghi and F. Fazio. (228) Myocardial Uptake and Kinetic Properties of Technetium 99m-Q3 in Dogs. J. Musl. . Mgd., H,169 bl 706 (1994). With M.C. Gerson, R.W. Millard, A.J. McGoron, M. Gabel, L.C. Washburn. D. Biniakiewicz, R.C. Elder and R.A. Walsh. (229) Kinetic Propenies of 99m Tc-Q12 in Canine Myocardium. Circulation. E9,1291-1300 (1994). With M.C. Gerson, R.W. Millard, N.J. Roszell, A.J. McGoron, M. Gabel, L. C. Washbum, D. Biniakiewicz, D. Blankenship, W.H. Mallin, R.C. Elder and R.A. Walsh. (230) Comparison of Technetium 99m Q12 and Thallium 201 for Detection of Angiographically Documented Coronary Artery Disease in Humans. l. Hugl. Cardiol.,1, ' 499 508 (1994). With M.C. Gerson, J. Lukes, D. Diniakiewicz, R.C. Rohe, L.C. Washbum, C. Fortman and R.A. Walsh. A Rob for Supramohcular Chemistry. In " Transition Metals in (231) Supramolecular Biomedical Targeting:istry", Chem L. Fabbrizzi and A. Poggi, eds, Kluwer Acad Publ., > Netherlands, 101 114 (1994). With K.M. Miller and S.R. Cooper. (232) Sensitive Absorbance Measurements of 99m Tc Imaging Agents Using a New Fiber Optic Sensor. Etes. SPIE Int. Seg. OpJ. ling., HH,335 343 (1994). With C.J. Seliskar, D.A. Landis and W.R. Heineman. (233) Radiolabeled somatostatin analogues. New J. Chem, H,365 369 (1994). With K.M. Miller. (234) Comparison ofImaging Properties of Technetium 99m Q12 and Technetium 99m Q3 in Humana. f.Hugl. Cardiol.,2,224 230(1995). With M.C. Gerson, J. Lukes, D. Biniakiewicz, L.C. Washburn, R.A. Walsh. (235) Biokinetics and Dosimetry Analysis in Healthy Volunteers for a Two Injection (Rest- . Stress) Protocol of the Myocardial Perfusion Imaging Agent Technetium 99m Labeled Q3 .1. Engl. Cardiol., 2, 395-404 (1995). With R.C. Rohe, S.R. Thomas, M.G. Stabin, M.C. Gerson, D.D. Cummings and H.R. Maxon, IH. (236) Perspectives on the History, Present and Possible Future of Technetium and Rhenium - Chemistry in Nuclear Medicine, in " Technetium and Rhenium in Chemistry and Nuclear Medicine. 4." M. Nicolini, G. Bandoli and U. Mazzi, eds., SGEditorial, Padova, Italy, xxv xxxv (1995). With M. Marmion. (237) The dependence of Ligand NMR Chemical Shift on the Identity of the Metal Center in Analogous Technetium and Rhenium complexes. In " Technetium and Rnenium in Chemistry and Nuclear Medicine. 4.", M. Nicolini, G. Bandoli and U. Mazzi, eds., SGEditorial, Padova, Italy,155 163 (1995). With F. Tisato, F. Refosco and M. Nicolini.
~ ir r --
Edward A. Deutsch j (238) Radiopharmaceutical Development of TechneScan Q12*. In " Technetium and
- Rhenium in Chemistry and Nuclear Medicine. 4.", hf. Nicolini, G. Bandoli and U. Maz2i, eds., SGEditorial, Padova. Italy,253 258 (1995). With M. Marmion, M. DeRosch, bl.
Bushman, R. Wolfangel, E. Webb and K. Deutsch. , (239) Nuclear, Chemical and Mechanistic Considerations in the Use of *"Sn(4+)-DTPA Relative to *Re HEDP and Other Agents for Bone Pain Therapy. In " Technetium and Rhenium in Chemistry and Nuclear Medicine. 4.", M. Nicolini, G. Bandoli and U. Mazzi, eds., SOEditorial, Padova, Italy,287 292 (1995). With S.C. Srivastava, G.E. Meinken, L.F. Mausner, C. Cutler and H.L. Atkins. (240) Diagnostic / Therapeutic Radioisotope Pairs: A Comparison of Tc 99m/Re 186 and In-111/Y 90 Targeted Radiopharmaceuticals. In "Techaetium and Rhenium in Chemistr and Nuclear Medicine. 4.". M. Nicolini, G. Bandoli and U. Mazzi, eds., SGEditorial, y Padova, Italy,457-467 (1995). With K.M. Miller. (241) Comparison ofImaging Properties of Tc 99m Ql2 and Tc 99m Q3 in Man. In
" Technetium and Rhemumm, Chemistry and Nuclear Medicine. 4.", M. Nicolini, G.
Bandoli and U. Mazzi, eds., SGEditorial, Padova, Italy,505-509 (1995). Wit! \1. Gerson, J. Lukes, D. Biniakiewicz, L. Washbum and R. Walsh. (242) Tracers and Contrast Agents in Cardiovascular Imaging: Present and Future. Ouanerly 1 Eng]. hied.,4._Q,121-131 (1996). With M. Marmion. (243) Cationic (""Tc"(DIARS)2(SR) ]' Complexes as Potential Myocardial Perfusion
. Chem.,33.,1253 1261 (1996). With F. Tisa(to, T. Maina, L R. Shao, .
(244) "'"Tc 2 GAM: A Tracer for Renal Imaging. Nuc). qq hkd. Biol.,21 927-933 (1996). With L. Gianolli, F. Dosio, M. Matarrese, F. Colombo, C. Cutler, D. Stepniak Biniakiewicz, A. Savi, G. Lucignani and F. Fazio. (245) Electrochemistry and Spectroelectrochemistry of[Re(1,2-bis (dimethylphosphine)- ethane)3)' . Inntg. Chim. Apa. 2f2,195-202 (1997). With J. R. Kirchhoff, M. R. Allen, , B. V. Cheesman, K. Okamoto and W. R. Heineman. (246) Application of Taube Insights to Nuclear Medicine: In Vivo Inorganic Chemistry. In
" Prom Electron Transfer Reactions: Inorganic, Organometallic, and Biological A plications", Advances in Chemistry Series 253, S.S. Isied, ed., Amer. Chem. Soc.,
% ashington, DC, pp. 423-431 (1997).
(247) Studies of the Structure and Composition of Rhenium 1,1 Hydroxglethylene-diphosphonate !HEDP) Analogues of the Radi,> therapeutic A:;ent 'ReHEDP. Inom. Chem. 3J$,3055-3063 (1997). With R. C. Elder, J. Yuan, B. Eelmer, D. Pipes and K. Deutsch e
.}}